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Practice Guidelines

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Acute Treatment of Hyperkalemia - Cochrane for Clinicians - American Family Physician

Nov 1, 2005 - According to disease-oriented evidence, insulin and intravenous glucose, inhaled albuterol (Ventolin), and dialysis are the best treatment options; the first two may be given in combination. Bicarbonate or resins are not recommended for routine use, particularly without one of the more ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1101/p1703.html

Advance Provision for Emergency Oral Contraception - Cochrane for Clinicians - American...

Sep 1, 2007 - Providing oral emergency contraceptives in advance to fertile women for use after unprotected sexual intercourse (i.e., advance provision) does not affect pregnancy rates, condom use, sexually transmitted infection rates, or type of contraception used. Advance provision more than ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0901/p654.html

Alendronate for Fracture Prevention in Postmenopause - Cochrane for Clinicians - ...

Sep 1, 2008 - In postmenopausal women, a 10-mg daily dose of alendronate is effective for secondary (number needed to treat [NNT] = 16) and primary (NNT = 50) prevention of vertebral fractures. It is also effective for secondary prevention of nonvertebral fractures, including hip or wrist fractures ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0901/p579.html

Amphetamines for Attention-Deficit/Hyperactivity Disorder in Adults - Cochrane for ...

Sep 1, 2012 - Amphetamines improve ADHD symptom severity but, when compared with placebo, they are associated with increased discontinuation rates because of adverse effects. There does not appear to be a difference among dosages or between the immediate- and sustained-release formulations.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0901/p413.html

Antibiotics for Sore Throat - Cochrane for Clinicians - American Family Physician

Jul 1, 2014 - Compared with placebo, antibiotics can shorten the duration of sore throat symptoms by about 16 hours and can reduce complications. In countries where the absolute rates of complications are higher, antibiotic therapy is more likely to be effective. The effectiveness of antibiotic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0701/p23.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jul 1, 2009 - Although LMWH appears to be more effective than oral anticoagulants in the prevention of recurrent VTE, this does not translate into a survival benefit. LMWH and oral anticoagulants have the same reported adverse events of bleeding and thrombocytopenia.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0701/p30.html

Antidepressants to Treat Nonspecific Low Back Pain - Cochrane for Clinicians - American...

Jul 1, 2008 - Although antidepressants have been shown to be superior to placebo in some forms of chronic pain, they do not reduce pain or improve functional status or depression in patients with nonspecific low back pain.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0701/p51.html

Are SSRIs Effective for Treating OCD? - Cochrane for Clinicians - American Family ...

May 1, 2008 - SSRIs are effective for the treatment of OCD. If it is assumed that 10 percent of persons with OCD will recover without treatment, then 12 persons with OCD need to be treated for one additional person to have a response within six to 13 weeks. If it is assumed that 20 percent of persons...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0501/p1252.html

Aripiprazole vs. Other Atypical Antipsychotics for Schizophrenia - Cochrane for ...

Jun 1, 2010 - Aripiprazole is less effective in treating schizophrenia than olanzapine (Zyprexa), but has fewer metabolic and sedative adverse effects. There is no difference in effectiveness between aripiprazole and risperidone (Risperdal); however, aripiprazole may be associated with less dystonia,...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0601/p1335.html

Buprenorphine Maintenance vs. Methadone Maintenance or Placebo for Opioid Use Disorder ...

Feb 1, 2015 - At dosages greater than 2 mg per day, buprenorphine maintains treatment retention better than placebo. When flexible dosing (doses adjusted based on patient symptoms) is used, the effectiveness of buprenorphine is comparable to that of methadone in suppressing opioid use.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0201/p165.html

Chewing Gum for Postoperative Recovery of Gastrointestinal Function - Cochrane for ...

Dec 1, 2015 - Having patients chew gum reduces the time to first flatus and time to first bowel movement, as well as the length of hospitalization by about half a day.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1201/p974.html

Clozapine vs. Other Atypical Antipsychotics for Schizophrenia - Cochrane for Clinicians...

Feb 1, 2011 - Although further trials are needed, there is some evidence that clozapine is slightly more effective than risperidone (Risperdal). Fewer participants taking clozapine dropped out of studies because of lack of effectiveness compared with those taking risperidone (number needed to treat =...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0201/p260.html

Cochrane for Clinicians - Apr 1, 2007 - American Family Physician

Apr 1, 2007 - Topical salicylic or lactic acid and cryotherapy are effective treatments for nongenital warts. Although cryotherapy is somewhat more effective, it is associated with more pain and blistering than salicylic or lactic acid. The spontaneous cure rate of nongenital warts is 50 to 70 ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0401/p1001a.html

Cochrane for Clinicians - Jul 1, 2006 - American Family Physician

Jul 1, 2006 - Intravenous lidocaine and oral mexiletine provide a modest reduction in neuropathic pain with no indication of serious adverse effects. However, safety data are limited because most studies were of relatively short duration and fewer than 400 patients have been studied in total for each...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0701/p79.html

Corticosteroids for the Treatment of Sore Throat - Cochrane for Clinicians - American ...

Jan 1, 2014 - In adults with suspected bacterial pharyngitis who require antibiotic therapy, adding a corticosteroid may increase the likelihood of complete pain resolution at 24 hours. Further study is needed to assess the safety of corticosteroids and whether they can be recommended for presumed ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0101/p14.html

Cranberry Products for Treatment of Urinary Tract Infection - Cochrane for Clinicians -...

Aug 1, 2008 - Over a 12-month period, cranberry products decrease the incidence of symptomatic urinary tract infections (UTIs), especially in women with recurrent UTIs. Optimal dosage and form of administration (juice, tablets, or capsules) is unclear. There are no studies comparing cranberry juice ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0801/p332.html

Early Invasive Therapy or Conservative Management for Unstable Angina or NSTEMI? - ...

Jan 1, 2007 - Compared with conservative management, early invasive treatment of patients with UA or NSTEMI using coronary angiography with or without revascularization reduces rehospitalization and refractory angina within the first year and significantly reduces mortality and myocardial infarction ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0101/p47.html

Effect of Cocoa on Blood Pressure - Cochrane for Clinicians - American Family Physician

Apr 1, 2013 - Consuming 50 g of cocoa daily will lower blood pressure 2 to 3 mm Hg on average in adults with hypertension. Evidence of improved patient-oriented outcomes does not exist.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0401/p484.html

Effectiveness of Antidepressants Compared with Placebo for Depression in Primary Care -...

Jul 1, 2010 - Tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs) are more effective than placebo for the treatment of depression in primary care settings.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0701/p42.html

Effectiveness of Calcium Channel Blockers for Raynaud Phenomenon - Cochrane for ...

Aug 1, 2014 - CCBs are modestly effective at reducing the frequency of attacks of primary Raynaud phenomenon. There is no evidence that attack severity or physiologic measurements are reduced by CCBs. Treatment is associated with adverse effects such as headache, flushing, and edema.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0801/p143.html

Effects of Altered Dietary Salt Intake in Patients with Chronic Kidney Disease - ...

Apr 1, 2017 - Reducing salt intake lowers blood pressure and reduces proteinuria in patients with CKD, but there is no evidence to determine whether lowering salt consumption leads to clinically significant reductions in end-stage renal disease, cardiovascular events, or all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0401/p423.html

Effects of Yoga in Patients with Asthma - Cochrane for Clinicians - American Family ...

Aug 1, 2017 - Regular yoga improves quality of life as measured on the Asthma Quality of Life Questionnaire (mean difference = 0.57 units on a seven-point scale; 95% confidence interval [CI], 0.37 to 0.77); improves asthma symptoms (standardized mean difference = 0.37; 95% CI, 0.09 to 0.65); and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0801/p159.html

Exercises for Mechanical Neck Disorders - Cochrane for Clinicians - American Family ...

Oct 1, 2006 - There is some evidence that a variety of exercises help patients with mechanical neck pain. Evidence is strongest for a multimodal approach that includes exercise and mobilization or manipulation of the cervical spine, although this research has been criticized for having an imperfect ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1001/p1126.html

Glucocorticoids for Treatment of Croup - Cochrane for Clinicians - American Family ...

Jan 1, 2005 - Compared with placebo, treatment with glucocorticoids results in reduced symptoms, less need for treatment with racemic epinephrine, fewer readmissions to emergency departments, and shorter hospital stays.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0101/p66.html

Impact of Industry Sponsorship on Research Outcomes - Cochrane for Clinicians - ...

Dec 1, 2013 - Are research studies sponsored by industry more likely to have favorable results and conclusions than studies without industry sponsorship?

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1201/p746.html

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