American Family Physician

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Cochrane for Clinicians

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Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Feb 1, 2006 - At high dosages, gabapentin is moderately effective for neuropathic pain, although adverse effects are experienced as often as benefit.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0201/p435.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jun 1, 2006 - An antidepressant such as imipramine (Tofranil) or sertraline (Zoloft), possibly with the addition of an antipsychotic, is the preferred initial pharmacologic treatment for psychotic depression.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0601/p1935.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jun 1, 2006 - For adult patients who are taking a minimum maintenance dosage of inhaled corticosteroid for asthma, adding a long-acting beta2 agonist permits reduction of the dosage of inhaled corticosteroid by 253 mcg beclomethasone equivalent per day without worsening the patient's symptoms. In ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0601/p1935a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Oct 1, 2007 - Providing early opioid analgesia to patients presenting with acute abdominal pain does not affect or delay management decisions, but it lessens pain intensity as rated by the patient.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2007/1001/p971.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Dec 1, 2004 - Combined evidence from two clinical trials of calcium supplementation lasting for several years revealed a reduced rate of recurrent colorectal adenoma. However, evidence is insufficient to recommend supplementation with dietary calcium for patients who have never had an adenoma.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2004/1201/p2109.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Mar 1, 2005 - NPH insulin and metformin taken at bedtime appears to be the most favorable combination studied, but this conclusion is based on poor-quality, inconsistent studies that measure disease-oriented outcomes. There are no data on the effect of these drug combinations on patient-oriented ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0301/p899.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Mar 1, 2005 - Treatment with betamimetics decreases the number of women with preterm labor who give birth within 48 hours, but it does not decrease the number of births within seven days. Limited evidence suggests that treatment with beta-mimetics does not decrease perinatal death or morbidity.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0301/p899a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2005 - Based on three good studies of 462 patients, discontinuing epidural analgesia in the second stage of labor does not significantly change rates of instrumented delivery or other delivery outcomes, but it increases rates of inadequate pain relief.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0401/p1303.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2005 - For empiric treatment of GERD or endoscopy-negative reflux disease, a short trial of a proton pump inhibitor increases the chance of remission. Histamine H2-receptor antagonists are less expensive and work well in many patients, particularly those with less severe symptoms or ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0401/p1303a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jun 1, 2005 - Thickened feeds and metoclopramide reduce symptoms of GER in normally developing infants. However, elevating the head of the crib appears to have no effect.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0601/p2091.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jun 1, 2005 - Many patients request delayed umbilical cord clamping in their birth plans. Delayed cord clamping allows continued perfusion while the baby transitions to newborn circulation. However, when an infant is high risk, physicians frequently clamp and cut the cord early to allow the neonatal ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/0601/p2091a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Oct 1, 2005 - Although no difference in effectiveness has been demonstrated in existing trials, too few patients have been studied to detect small but clinically important differences in pregnancy rates. Low-dose estrogen pills have higher rates of discontinuation and bleeding disturbances.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/1001/p1224a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Oct 1, 2005 - There is limited, weak evidence that a low glycemic index diet improves risk factors for CHD, but there are no randomized controlled trials (RCTs) showing a reduction in morbidity or mortality.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/1001/p1224.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Dec 1, 2005 - Three days of antibiotic therapy is as effective as longer courses for treatment of uncomplicated UTIs in women.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/1201/p2219.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Dec 1, 2005 - In patients with moderate or severe COPD, tiotropium reduces exacerbations, hospitalizations, and symptom scores and improves health-related quality of life compared with placebo and ipratropium (Atrovent). However, more study is needed to determine tiotropium’s role in the treatment of...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2005/1201/p2219a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Feb 1, 2006 - Combined with methotrexate, subcutaneous adalimumab at a dosage of 40 mg every two weeks slows the progression of rheumatoid arthritis at one year. The combination is more effective than adalimumab monotherapy. Limited evidence suggests that adalimumab is also safe and effective when ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0201/p435a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2006 - Benzodiazepines are safe and effective for the treatment of alcohol withdrawal, particularly for the prevention of withdrawal seizures, although their superiority to anticonvulsants has not been demonstrated convincingly. There is no clear benefit of one benzodiazepine over another or ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0401/p1191.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2006 - The single clinical trial on this topic found that inhaled beta agonists do not reduce cough frequency or improve symptoms in children with chronic, nonspecific cough.

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0401/p1191a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jul 1, 2006 - Intravenous lidocaine and oral mexiletine provide a modest reduction in neuropathic pain with no indication of serious adverse effects. However, safety data are limited because most studies were of relatively short duration and fewer than 400 patients have been studied in total for each...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0701/p79.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Jul 1, 2006 - Induction of labor in patients with PROM does not increase the rates of cesarean delivery or operative vaginal delivery. Among patients who are induced there is a slightly lower incidence of chorioamnionitis (relative risk [RR] 0.74; 95% confidence interval [CI], 0.56 to 0.97) and a ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2006/0701/p79a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2007 - Topical salicylic or lactic acid and cryotherapy are effective treatments for nongenital warts. Although cryotherapy is somewhat more effective, it is associated with more pain and blistering than salicylic or lactic acid. The spontaneous cure rate of nongenital warts is 50 to 70 ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2007/0401/p1001a.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Apr 1, 2007 - Children with otitis media with effusion do not benefit from decongestants or antihistamines. Common adverse effects of these therapies are gastrointestinal upset, irritability, drowsiness, and dizziness (number needed to harm = 9).

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2007/0401/p1001.html

Cochrane for Clinicians: Cochrane for Clinicians - American Family Physician

Oct 1, 2007 - There are no randomized controlled trials (RCTs) of labor induction in women with a low–transverse uterine scar. Observational studies indicate that there is a small increased risk of uterine rupture and adverse fetal outcomes, especially in women induced with prostaglandins. Although ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2007/1001/p971a.html

Cochrane for Clinicians: Effectiveness of Bronchodilators for Bronchiolitis ...

May 1, 2011 - Bronchodilators may transiently improve the clinical status of infants with bronchiolitis and no prior history of wheezing. However, moderately strong evidence shows that key outcomes such as oxygen saturation, need for hospitalization, length of hospitalization, and duration of ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2011/0501/p1045.html

Cochrane for Clinicians: Are Neuraminidase Inhibitors Effective for Preventing and ...

Oct 1, 2012 - Treating previously healthy patients with oseltamivir (Tamiflu) reduces the duration of influenza symptoms by approximately 21 hours, but it does not reduce the risk of hospitalization in this population.1 The data are insufficient to determine whether oseltamivir reduces the ...

American Family Physician : Cochrane for Clinicians

http://www.aafp.org/afp/2012/1001/p624.html

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