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POEMs

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POEMs: Single-Dose Dexamethasone an Option for Acute Adult Asthma - American Family ...

Mar 15, 2017 - A single dose of 12-mg dexamethasone, which has a longer duration of action than prednisone, is almost as effective as five days of 60-mg prednisone for the prevention of relapse in adults with acute asthma treated in an emergency department.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0315/od1.html

POEMs: Antipsychotics Worsen Symptoms in Patients with Delirium Who Receive Palliative ...

Mar 15, 2017 - For hospitalized patients with acute delirium and symptoms of distress who are receiving palliative care, the use of risperidone (Risperdal) or haloperidol at conservative oral doses worsens symptoms and may shorten overall survival.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0315/od3.html

POEMs: Detrimental Effect of Tight Glucose Control on CV Mortality Persists Over Nine ...

Mar 15, 2017 - The initial Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, which compared standard treatment with intensive control, found that despite good intentions, cardiovascular (CV) and overall mortality are significantly higher when blood glucose levels are lower.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0315/od2.html

POEMs: Semaglutide Reduces CV Events in High-Risk Patients with Type 2 Diabetes ...

Mar 15, 2017 - Semaglutide significantly reduced the composite outcome of CV death, nonfatal myocardial infarction, and nonfatal stroke (number needed to treat [NNT] = 43 over 2.1 years). It was generally well tolerated, and it reduced body weight by approximately 6.4 to 9.5 lb (2.9 to 4.3 kg).

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0315/p396.html

POEMs: Steroids at 34 to 36 Weeks’ and Before Term Cesarean Decrease Respiratory ...

Feb 15, 2017 - For women admitted for imminent premature delivery at 34 to 36 weeks of gestation, one or two doses of betamethasone or dexamethasone (8 to 12 mg) decrease the likelihood of neonatal respiratory distress syndrome and shorten lengths of stay in the intensive care unit.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0215/od2.html

POEMs: Chocolate Consumption May Make Acne Vulgaris Worse - American Family Physician

Jan 15, 2017 - This study found a statistically significant increase in facial acne lesions among college students 48 hours after ingesting chocolate instead of jelly beans (average compared with baseline: 4.8 new lesions vs. 0.7 fewer lesions, respectively).

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0115/p122a.html

POEMs: Active Surveillance for Localized Prostate Cancer: No Increased Mortality, but ...

Feb 1, 2017 - This landmark study compared active surveillance with radical prostatectomy or radiation therapy for patients with T1c or T2 prostate cancer. The benefits of active surveillance include avoiding radical therapy in one-half of the patients, with no effect on disease-specific survival or ...

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0201/p196.html

POEMs: Brief Interventions for Weight Management in Kids Are Not Effective - American ...

Feb 1, 2017 - Calculating the BMI of children and adolescents in primary care practices and counseling those who are overweight is ineffective to reduce BMI in children over several years of follow-up.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0201/p194a.html

POEMs: Tamsulosin Beneficial for Passage of 5- to 10-mm Distal Ureteral Stones - ...

Jan 15, 2017 - Tamsulosin promotes stone passage of distal ureteral stones that are 5 to 10 mm in size. You would need to treat five such patients to get one stone passage. Smaller stones tend to pass on their own at a rate of 86% in this study.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0115/p123a.html

POEMs: Sertraline Reduces Risk of Depression in Adults After Traumatic Brain Injury - ...

Feb 1, 2017 - This study found that sertraline is more effective than placebo (number needed to treat = 6) in preventing the onset of a major depressive disorder in adults following a TBI. This study included patients with mild, moderate, and severe TBI.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0201/p194.html

POEMs: Hypertensive Urgency Not Really an Urgent Problem - American Family Physician

Nov 1, 2016 - It seems that rapid treatment of patients with hypertensive urgency is unsuccessful and unnecessary. In this study of almost 60,000 patients, 80% did not have controlled blood pressure (less than 140/90 mm Hg) after one month of treatment, including patients who were hospitalized. On ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1101/p750a.html

POEMs: CA 125 Relatively Specific for Diagnosing Endometriosis - American Family Physician

Jan 15, 2017 - For women with symptoms suggestive of endometriosis, serum CA 125 is a relatively specific (93%) and noninvasive test. It can be used to make a presumptive diagnosis in cases for which a medical management approach is being considered without having to perform a (diagnostic standard) ...

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0115/p122.html

POEMs: In Patients with Vascular Disease, Treating Sleep Apnea Does Not Reduce the Risk...

Jan 15, 2017 - Compared with usual care, the use of CPAP provides a modest improvement in daytime sleepiness, but does not reduce the likelihood of cardiovascular events, even in a high-risk population.

American Family Physician : POEMs

http://www.aafp.org/afp/2017/0115/p123.html

POEMs: Lumbar Fusion No Better Than Exercise and Therapy in the Long Term - American ...

Dec 1, 2016 - This trial is a good example of how to do just about everything wrong to get the results you want. The authors did not conceal allocation, did not mask anyone in the study, used an unvalidated and subjective primary outcome, and downplayed the intention-to-treat analysis. Funding for ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1201/p937.html

POEMs: Step-by-Step Approach to Ruling Out Infant Infection Is Accurate - American ...

Dec 1, 2016 - The Step-by-Step approach, using a basic physical examination and readily available urine and blood tests (without lumbar puncture; see the Synopsis section), can successfully identify low-risk infants younger than 90 days who will not need empiric antibiotic treatment and lumbar ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1201/p933.html

POEMs: Opioid Analgesia Hard to Tolerate and Not Effective for Chronic Low Back Pain - ...

Nov 1, 2016 - Effective pain control in patients with low back pain is still elusive. Approximately one-half of all patients with low back pain who take an opioid analgesic will stop treatment because of ineffectiveness or adverse effects. Patients staying the course will experience, on average, a ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1101/p753.html

POEMs: Procalcitonin Guidance Safely Decreases Antibiotic Use in Critically Ill ...

Oct 15, 2016 - For patients in the intensive care unit (ICU) who receive antibiotics for presumed or proven bacterial infections, the use of procalcitonin levels to determine when to stop antibiotic therapy results in decreased duration and consumption of antibiotics without increasing mortality.

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1015/p663a.html

POEMs: Cervical Treatment Associated with Adverse Obstetric Outcomes - American Family ...

Dec 1, 2016 - Cervical treatments for dysplasia and early cervical carcinoma are associated with subsequent risk of preterm birth. Excisional treatments carry higher risk than ablative treatments, and multiple treatments carry higher risk than single treatments. The frequency and severity of ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1201/p933a.html

POEMs: Larger Bottles Associated with Greater Weight in Infants - American Family ...

Dec 1, 2016 - In nonbreastfed infants, using large bottles (at least 6 oz [180 mL]) to feed infants two months of age was associated with greater weight gain by six months of age. The authors did not report adverse effects associated with bottle size. This is an interesting study that suggests that ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1201/p936.html

POEMs: Getting an Infant to Sleep: Graduated Extinction and Sleep Fading are Effective ...

Nov 1, 2016 - This study found that graduated extinction (increasing intervals between comforting the infant) and sleep fading (putting the child to bed progressively later until the parent finds the sweet spot) are both effective at decreasing sleep latency and the number of awakenings and ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1101/p750.html

POEMs: Venous Samples Are a Less-Painful Starting Point for the Evaluation of Patients ...

Nov 1, 2016 - There is very good agreement between arterial and venous measurements of pH and bicarbonate, and fairly good agreement at higher levels between arterial and peripheral measures of oxygen saturation. These authors suggest an algorithm for patients with acute exacerbation of COPD that ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1101/p757.html

POEMs: Third-Generation Oral Contraceptives Associated with Greater Risk of PE, Stroke,...

Oct 15, 2016 - Although there is risk with any current oral contraceptive combination, those that contain lower doses of estrogen, and levonorgestrel instead of desogestrel or gestodene, are associated with the least risk of ischemic stroke, myocardial infarction (MI), or pulmonary embolism (PE). ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1015/p663.html

POEMs: Low-Dose Morphine Less Effective Than Diclofenac or Acetaminophen for Renal ...

Oct 15, 2016 - This is a good example of how a well-done study can lead to erroneous conclusions. The comparator most likely to be effective here—titrated morphine—was used at a low dose and found to be less effective than intramuscular diclofenac or intravenous paracetamol (acetaminophen).

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1015/p665.html

POEMs: All Analgesics Are Better Than Placebo in Patients with Knee or Hip DJD - ...

Oct 15, 2016 - In patients with hip or knee DJD, all analgesics are more effective than placebo in relieving pain and improving function. Although paracetamol (acetaminophen) is the least effective of all the drugs studied, it still may be the first treatment for these patients because of its safety ...

American Family Physician : POEMs

http://www.aafp.org/afp/2016/1015/p664.html

POEMs: CBT Effective in Adolescents with Depression Who Do Not Want Medication - ...

Sep 1, 2016 - In adolescents who eschew drug treatment of major depression, short-term CBT is more effective than treatment as usual in inducing recovery, with a number needed to treat of 4 to 10. CBT also produced faster results.

American Family Physician : POEMs

http://www.aafp.org/afp/2016/0901/p384.html

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