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hypertension

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ACE Inhibitors vs. ARBs for Patients with Diabetic Kidney Disease - Cochrane for ...

Jul 1, 2007 - Studies comparing ACE inhibitors or ARBs with placebo found no mortality benefit in patients with diabetic kidney disease. A subgroup analysis of five studies (2,034 total patients) found that, when given at full or maximally tolerated doses, ACE inhibitors reduce all-cause mortality ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0701/p68.html

ACE Inhibitors vs. ARBs for Primary Hypertension - Cochrane for Clinicians - American ...

Apr 15, 2015 - ACE inhibitors and ARBs have similar effects on cardiovascular outcomes and total mortality in head-to-head trials. However, slightly more adverse effects were noted in patients assigned to ACE inhibitor therapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0415/p522.html

Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Antioxidant Supplements Do Not Improve Mortality and May Cause Harm - Cochrane for ...

Nov 1, 2008 - In randomized controlled trials of primary and secondary prevention, vitamins A and E, and beta-carotene supplementation increased mortality. Vitamin C and selenium supplementation had no significant effect on mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/1101/p1079.html

Antiplatelet Therapy and Anticoagulation in Patients with Hypertension - Cochrane for ...

Mar 1, 2005 - Antiplatelet agents should not be used in patients with hypertension and no previous history of heart attack or stroke. However, these agents are recommended for use in hypertensive patients who already have vascular disease. Anticoagulants should not be used for prevention of vascular ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p897.html

Are Beta Blockers Effective First-line Treatments for Hypertension? - Cochrane for ...

Nov 1, 2007 - Current evidence does not support the use of beta blockers as initial therapy for hypertension.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1101/p1306.html

Are Metered-Dose Inhalers with Holding Chambers Better Than Nebulizers for Treating ...

Jan 1, 2003 - In the emergency room, MDIs with holding chambers are as effective as nebulizers for delivering beta2 agonists to treat acute asthma in adults and children older than age two. There might be slightly less beta2 agonist–induced tachycardia in children when MDIs with holding chambers are ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0101/p62.html

Aripiprazole vs. Other Atypical Antipsychotics for Schizophrenia - Cochrane for ...

Jun 1, 2010 - Aripiprazole is less effective in treating schizophrenia than olanzapine (Zyprexa), but has fewer metabolic and sedative adverse effects. There is no difference in effectiveness between aripiprazole and risperidone (Risperdal); however, aripiprazole may be associated with less dystonia,...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0601/p1335.html

Beta-Blocker Use in Patients with COPD - Cochrane for Clinicians - American Family ...

Dec 1, 2006 - In 20 studies of cardioselective beta blockers in patients with COPD, participants had no adverse pulmonary or respiratory effects. Because of their salutary cardiovascular effects, cardioselective beta blockers should not be withheld from patients with COPD.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1201/p1858.html

Beta2 Agonists for Acute Cough or a Clinical Diagnosis of Acute Bronchitis - Cochrane ...

May 1, 2017 - There is insufficient evidence to determine whether beta2 agonists can improve symptoms for children with acute cough or bronchitis with wheeze. Beta2 agonists are not likely to benefit and may cause adverse effects in adults who do not have evidence of airflow restriction (number ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0501/p551.html

Blood Pressure Targets for Patients with Hypertension and Cardiovascular Disease - ...

Sep 1, 2018 - Achieving a target BP of 135/85 mm Hg or less does not decrease the risk of total cardiovascular events vs. treating to a target of 140 to 160/90 to 100 mm Hg. Further, treating to the lower BP target does not improve total mortality, cardiovascular mortality, or serious adverse effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0901/p276.html

Blood Pressure Treatment Targets for Uncomplicated Hypertension - Cochrane for ...

Apr 1, 2010 - To date, there is no evidence to support treating patients with uncomplicated hypertension to blood pressure goals lower than the standard blood pressure target of less than or equal to 140 to 160/90 to 100 mm Hg. In randomized controlled trials, patients treated to lower blood pressure...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0401/p848.html

Calcium Supplementation for Preventing Hypertensive Disorders in Pregnancy - Cochrane ...

Oct 1, 2015 - High-dose calcium supplementation (i.e., at least 1,000 mg per day) during pregnancy reduces the risk of developing hypertension and preeclampsia. The most significant risk reduction occurs in women at risk of hypertensive disorders and those with low-calcium diets.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1001/p570.html

Cochrane for Clinicians - Jun 1, 2005 - American Family Physician

Jun 1, 2005 - Thickened feeds and metoclopramide reduce symptoms of GER in normally developing infants. However, elevating the head of the crib appears to have no effect.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0601/p2091.html

Cochrane for Clinicians - Mar 1, 2005 - American Family Physician

Mar 1, 2005 - NPH insulin and metformin taken at bedtime appears to be the most favorable combination studied, but this conclusion is based on poor-quality, inconsistent studies that measure disease-oriented outcomes. There are no data on the effect of these drug combinations on patient-oriented ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p899.html

Cochrane for Clinicians - Oct 1, 2005 - American Family Physician

Oct 1, 2005 - Although no difference in effectiveness has been demonstrated in existing trials, too few patients have been studied to detect small but clinically important differences in pregnancy rates. Low-dose estrogen pills have higher rates of discontinuation and bleeding disturbances.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1001/p1224a.html

Delaying Antibiotics for Respiratory Infections - Cochrane for Clinicians - American ...

Feb 1, 2005 - Delayed prescribing appears to be a reasonable and safe option in patients with cough and in those who do not appear very ill, but it cannot be recommended for children with sore throat unless streptococcal pharyngitis has been ruled out. Delayed prescribing of antibiotics results in a ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0201/p466.html

Different Durations of Corticosteroid Therapy for COPD Exacerbations - Cochrane for ...

Mar 1, 2019 - Treatment of acute exacerbations of COPD with a shorter course of systemic corticosteroids (seven or fewer days) is likely to be as effective and safe as treating with longer courses (more than seven days).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0301/p295.html

Effect of Cocoa on Blood Pressure - Cochrane for Clinicians - American Family Physician

Apr 1, 2013 - Consuming 50 g of cocoa daily will lower blood pressure 2 to 3 mm Hg on average in adults with hypertension. Evidence of improved patient-oriented outcomes does not exist.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0401/p484.html

Effectiveness and Safety of Factor Xa Inhibitors in Patients with Atrial Fibrillation -...

Oct 1, 2019 - Treatment of AFib with a factor Xa inhibitor results in a decrease in the combined end point of stroke and embolic events (odds ratio [OR] = 0.89; 95% CI, 0.82 to 0.97), as well as a decrease in intracranial hemorrhage (OR = 0.50; 95% CI, 0.42 to 0.59) and all-cause mortality (OR = ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p405.html

Effectiveness of Acamprosate in the Treatment of Alcohol Dependence - Cochrane for ...

Mar 1, 2011 - When used in conjunction with detoxification and psychosocial interventions for treating alcohol dependence, acamprosate can reduce the risk of any return to drinking and improve cumulative abstinence rates.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0301/p522.html

Effectiveness of Bronchodilators for Bronchiolitis Treatment - Cochrane for Clinicians ...

May 1, 2011 - Bronchodilators may transiently improve the clinical status of infants with bronchiolitis and no prior history of wheezing. However, moderately strong evidence shows that key outcomes such as oxygen saturation, need for hospitalization, length of hospitalization, and duration of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0501/p1045.html

Effectiveness of Insulin Sensitizing Drugs for Polycystic Ovary Syndrome - Cochrane for...

Nov 1, 2007 - Insulin sensitizing drugs are more effective than oral contraceptives alone at improving fasting insulin levels in patients with PCOS. Compared with metformin (Glucophage) alone, oral contraceptives alone better control irregular menstrual cycles and reduce androgen levels. There is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1101/p1308.html

Effects of Altered Dietary Salt Intake in Patients with Chronic Kidney Disease - ...

Apr 1, 2017 - Reducing salt intake lowers blood pressure and reduces proteinuria in patients with CKD, but there is no evidence to determine whether lowering salt consumption leads to clinically significant reductions in end-stage renal disease, cardiovascular events, or all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0401/p423.html

Exercise is an Effective Intervention in Overweight and Obese Patients - Cochrane for ...

May 1, 2007 - Exercise leads to a weight loss of 1 lb, 2 oz to 16 lb, 12 oz (0.5 to 7.6 kg), compared with a 3-oz (0.1-kg) weight loss to a weight gain of 1 lb, 9 oz (0.7 kg) with no treatment. Patients participating in higher-intensity exercise lose 3 lb, 5 oz (1.5 kg) more than those participating ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0501/p1333.html

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