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Different Durations of Corticosteroid Therapy for COPD Exacerbations - Cochrane for ...

Mar 1, 2019 - Treatment of acute exacerbations of COPD with a shorter course of systemic corticosteroids (seven or fewer days) is likely to be as effective and safe as treating with longer courses (more than seven days).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0301/p295.html

Deep Venous Thrombosis: Home vs. Inpatient Treatment - Cochrane for Clinicians - ...

Dec 1, 2018 - Patients treated at home with low-molecular-weight heparin (LMWH) have lower rates of recurrent VTE than those treated in a hospital.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/1201/p642.html

Culture-Specific Asthma Education Programs for Minority Groups - Cochrane for ...

Nov 1, 2018 - In children from minority groups, culture-specific asthma education programs (CAEPs) reduce the number of severe asthma exacerbations requiring hospitalization and improve asthma control as measured by the Childhood Asthma Control Test but not the Asthma Control Questionnaire. CAEPs ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/1101/p572.html

Procalcitonin to Guide Antibiotic Therapy in Acute Respiratory Infections - Cochrane ...

Jul 1, 2018 - Procalcitonin-guided antibiotic therapy, when compared with routine treatments, results in decreased mortality in patients with acute respiratory infections (absolute risk reduction [ARR] = 1.4%; number needed to treat [NNT] = 71).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0701/p20.html

Individual Behavioral Counseling for Smoking Cessation - Cochrane for Clinicians - ...

Jul 1, 2018 - Individual behavioral counseling conducted by a trained therapist provides some benefit when compared with brief counseling and support; however, this benefit is less pronounced in the context of pharmacotherapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0701/p21.html

Written Action Plans for Self-Management of COPD Exacerbations - Cochrane for ...

Mar 1, 2018 - Written self-management plans, especially those that include guidance on smoking cessation, increase health-related quality of life in patients with COPD. They also decrease the need for respiratory-related hospital admissions among patients with high or low baseline risk.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0301/p310.html

Interventions for Tobacco Cessation in Patients Being Treated for or Recovering from ...

Nov 1, 2017 - Pharmacotherapy alone and pharmacotherapy plus counseling are effective for tobacco cessation among patients being treated for or recovering from alcohol and substance use disorders. Counseling interventions without pharmacotherapy are not effective for tobacco cessation among patients ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/1101/p572.html

Vitamin D for the Management of Asthma - Cochrane for Clinicians - American Family ...

Sep 1, 2017 - Despite the authors' caution that further data are needed to clarify the role of vitamin D in care, this Cochrane review found that its use reduces the average number of asthma exacerbations requiring corticosteroid treatment from 0.44 to 0.28 per person per year.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0901/p290.html

Effects of Yoga in Patients with Asthma - Cochrane for Clinicians - American Family ...

Aug 1, 2017 - Regular yoga improves quality of life as measured on the Asthma Quality of Life Questionnaire (mean difference = 0.57 units on a seven-point scale; 95% confidence interval [CI], 0.37 to 0.77); improves asthma symptoms (standardized mean difference = 0.37; 95% CI, 0.09 to 0.65); and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0801/p159.html

Beta2 Agonists for Acute Cough or a Clinical Diagnosis of Acute Bronchitis - Cochrane ...

May 1, 2017 - There is insufficient evidence to determine whether beta2 agonists can improve symptoms for children with acute cough or bronchitis with wheeze. Beta2 agonists are not likely to benefit and may cause adverse effects in adults who do not have evidence of airflow restriction (number ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0501/p551.html

Interventions to Facilitate Shared Decision Making to Address Antibiotic Use for Acute ...

Jan 1, 2017 - Interventions to facilitate shared decision making reduce the prescribing of antibiotics for acute respiratory tract infections in the short term (within six weeks of the consultation) without increasing return visits or decreasing patient satisfaction (number needed to treat [NNT] = 6).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0101/p11.html

Intermittent Inhaled Corticosteroid Therapy for Mild Persistent Asthma in Children and ...

Jul 1, 2016 - Intermittent inhaled corticosteroid therapy reduces the risk of asthma exacerbations in children and adults with mild persistent asthma. Intermittent use appears to be safe in these patients.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0701/p21.html

Honey for Acute Cough in Children - Cochrane for Clinicians - American Family Physician

Jul 1, 2016 - For patients one to 18 years of age, providing honey for cough symptoms can reduce the frequency and severity of cough, as well as improve sleep for patients and parents, when compared with placebo or no treatment. Honey is no better than dextromethorphan for symptom control.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0701/p20.html

Electronic Cigarettes for Smoking Cessation - Cochrane for Clinicians - American Family...

Feb 1, 2016 - Electronic cigarettes with nicotine increase smoking cessation rates compared with placebo, with effectiveness similar to that of nicotine patches. In addition, more patients using electronic cigarettes with nicotine were able to halve their use of cigarettes than those using placebo ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0201/p178.html

Point-of-Care C-Reactive Protein Testing to Help Guide Treatment of Acute Respiratory ...

Oct 1, 2015 - Point-of-care C-reactive protein (CRP) testing used as an adjunct to a physician's clinical examination can modestly reduce antibiotic use. Measurement of CRP to guide antibiotic prescription does not appear to affect the duration of illness or recovery, although one study suggests that...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1001/p571.html

Aclidinium for Stable COPD - Cochrane for Clinicians - American Family Physician

Jun 1, 2015 - Aclidinium did not decrease all-cause mortality or exacerbations requiring oral steroids, antibiotics, or both. However, aclidinium decreased the number of patients with exacerbations requiring hospitalization and improved quality of life in those with stable COPD.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0601/p760.html

Safety of Long-Acting Beta Agonists in Adults with Asthma - Cochrane for Clinicians - ...

Oct 1, 2014 - LABAs appear to be safe when used with inhaled corticosteroids. LABA monotherapy is associated with an increase in asthma-related mortality and nonfatal serious adverse events, but not in all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/1001/p453.html

Bronchodilators for Bronchiolitis - Cochrane for Clinicians - American Family Physician

Nov 1, 2014 - Albuterol does not improve any clinical outcomes in the outpatient or inpatient setting and should not be used in the treatment of bronchiolitis in a child 24 months or younger.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/1101/p622.html

Prophylactic Antibiotics for the Prevention of COPD Exacerbation - Cochrane for ...

Jun 1, 2014 - Continuous prophylactic antibiotic therapy significantly decreases COPD exacerbations for up to three years. However, it does not decrease mortality, and it puts the patient at risk of antibiotic-resistant colonization and infection.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0601/p870.html

Role of Breathing Exercises in the Treatment of COPD - Cochrane for Clinicians - ...

Jan 1, 2014 - Patients with COPD who are treated with breathing exercises vs. standard care showed an improvement in exercise capacity, with inconsistent changes in dyspnea and health-related quality of life. Adding breathing exercises to a pulmonary rehabilitation program did not show any increased ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0101/p15.html

Physical Training for Patients with Asthma - Cochrane for Clinicians - American Family ...

Mar 1, 2013 - Physical training lasting for at least 20 to 30 minutes, two to three times a week for at least six weeks, improves physical fitness in patients with asthma. Physical training is not associated with worsening of asthma symptoms, and it improves health-related quality of life.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0301/p313.html

GERD Treatment for Chronic Nonspecific Cough in Children and Adults - Cochrane for ...

Sep 1, 2011 - Acid suppressants or prokinetic agents should not be used to treat chronic nonspecific cough in infants or children. There is insufficient evidence to support or discourage use of these agents to treat chronic non-specific cough in adults, even in those with a history of GERD.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0901/p502.html

Effectiveness of Bronchodilators for Bronchiolitis Treatment - Cochrane for Clinicians ...

May 1, 2011 - Bronchodilators may transiently improve the clinical status of infants with bronchiolitis and no prior history of wheezing. However, moderately strong evidence shows that key outcomes such as oxygen saturation, need for hospitalization, length of hospitalization, and duration of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0501/p1045.html

Chest Physiotherapy for Pneumonia in Adults - Cochrane for Clinicians - American Family...

Dec 1, 2010 - There is little evidence to support the effectiveness of chest physiotherapy for adults with pneumonia. In two small studies by the same investigator, only osteopathic manipulation was shown to improve some outcomes (i.e., length of stay and duration of antibiotic therapy).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/1201/p1340.html

Leg Compression and Pharmacologic Prophylaxis for Venous Thromboembolism Prevention in ...

Feb 1, 2010 - Based on high-quality evidence, the Cochrane review showed that combining IPC with pharmacologic prophylaxis was more effective than a single preventative measure for preventing deep venous thrombosis (DVT), and more effective than IPC alone for preventing pulmonary embolism (PE).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0201/p284.html

Addition of Long-Acting Beta Agonists for Asthma in Children - Cochrane for Clinicians ...

Mar 1, 2010 - In children with persistent asthma who are already taking inhaled corticosteroids, the addition of a LABA does not lower the rate of exacerbations requiring oral steroids, rescue medication, or hospitalizations, but it improves measurable lung function.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0301/p598.html

Should Salmeterol Be Used for Long-Term Asthma Control? - Cochrane for Clinicians - ...

Jun 1, 2009 - Salmeterol may help improve asthma symptoms, but it should only be used as part of a comprehensive asthma management plan including inhaled corticosteroids and a short-acting beta agonist. There is currently insufficient evidence to confirm that salmeterol does not increase the risk of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0601/p957.html

Over-the-Counter Medications for Acute Cough Symptoms - Cochrane for Clinicians - ...

Jul 1, 2008 - It is uncertain whether OTC cough medications are effective in reducing cough symptoms in adults; in children, no trials show a statistically significant benefit in the treatment compared with the placebo groups. Overall, the quality of evidence is poor; adult studies show conflicting ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0701/p52.html

Use of Inhaled Corticosteroids to Treat Stable COPD - Cochrane for Clinicians - ...

Jun 1, 2008 - Although the use of inhaled corticosteroids for COPD will not reduce mortality or affect long-term disease progression, inhaled corticosteroids can be useful for reducing COPD exacerbations and slowing declines in quality of life.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0601/p1532.html

Telephone Counseling Improves Smoking Cessation Rates - Cochrane for Clinicians - ...

Mar 1, 2007 - Telephone counseling can improve long-term smoking cessation rates. Multiple proactive calls are more effective than a single reactive call.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0301/p650.html

Beta-Blocker Use in Patients with COPD - Cochrane for Clinicians - American Family ...

Dec 1, 2006 - In 20 studies of cardioselective beta blockers in patients with COPD, participants had no adverse pulmonary or respiratory effects. Because of their salutary cardiovascular effects, cardioselective beta blockers should not be withheld from patients with COPD.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1201/p1858.html

Antibiotics for Exacerbations of COPD - Cochrane for Clinicians - American Family ...

Sep 1, 2006 - There is consistent evidence from a small number of studies that antibiotics significantly reduce mortality (number needed to treat [NNT] = 8) and treatment failure (NNT = 3) in more severely ill patients with COPD who are hospitalized because of an exacerbation. Two smaller studies ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0901/p749.html

Cochrane for Clinicians - Jun 1, 2006 - American Family Physician

Jun 1, 2006 - An antidepressant such as imipramine (Tofranil) or sertraline (Zoloft), possibly with the addition of an antipsychotic, is the preferred initial pharmacologic treatment for psychotic depression.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0601/p1935.html

Cochrane for Clinicians - Jun 1, 2006 - American Family Physician

Jun 1, 2006 - For adult patients who are taking a minimum maintenance dosage of inhaled corticosteroid for asthma, adding a long-acting beta2 agonist permits reduction of the dosage of inhaled corticosteroid by 253 mcg beclomethasone equivalent per day without worsening the patient's symptoms. In ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0601/p1935a.html

Cochrane for Clinicians - Apr 1, 2006 - American Family Physician

Apr 1, 2006 - Benzodiazepines are safe and effective for the treatment of alcohol withdrawal, particularly for the prevention of withdrawal seizures, although their superiority to anticonvulsants has not been demonstrated convincingly. There is no clear benefit of one benzodiazepine over another or ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0401/p1191.html

Cochrane for Clinicians - Apr 1, 2006 - American Family Physician

Apr 1, 2006 - The single clinical trial on this topic found that inhaled beta agonists do not reduce cough frequency or improve symptoms in children with chronic, nonspecific cough.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0401/p1191a.html

Oral Appliances for Obstructive Sleep Apnea? - Cochrane for Clinicians - American ...

Mar 1, 2006 - Although oral appliances provide improved subjective sleepiness and sleep-disordered breathing, continuous positive airway pressure (CPAP) is more effective. Oral appliances should not be used as a first-line treatment but rather should be reserved for patients who cannot tolerate CPAP ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0301/p801.html

Cochrane for Clinicians - Dec 1, 2005 - American Family Physician

Dec 1, 2005 - Three days of antibiotic therapy is as effective as longer courses for treatment of uncomplicated UTIs in women.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1201/p2219.html

Cochrane for Clinicians - Dec 1, 2005 - American Family Physician

Dec 1, 2005 - In patients with moderate or severe COPD, tiotropium reduces exacerbations, hospitalizations, and symptom scores and improves health-related quality of life compared with placebo and ipratropium (Atrovent). However, more study is needed to determine tiotropium’s role in the treatment of...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1201/p2219a.html

Corticosteroids for Pulmonary Sarcoidosis - Cochrane for Clinicians - American Family ...

Nov 1, 2005 - Patients who take oral corticosteroids are more likely to show improvement in their chest radiographs than those taking placebo, although improvements in symptoms and lung function are less certain. The typical dosage used in randomized trials was 20 mg daily or 40 mg every two days ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1101/p1702.html

Systemic Corticosteroids for Acute Exacerbations of COPD - Cochrane for Clinicians - ...

Aug 1, 2005 - Systemic corticosteroids improve symptoms of acute COPD exacerbations at three days and reduce the likelihood of treatment failure. There is no evidence that they reduce mortality or prevent recurrence at 30 days, but the existing studies may be too small to detect such a benefit. ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0801/p437.html

Low-Molecular-Weight Heparin for Initial Treatment of Venous Thromboembolism - Cochrane...

Jul 1, 2005 - LMWH is safer and more effective than unfractionated heparin for initial treatment of venous thromboembolism.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0701/p75.html

Delaying Antibiotics for Respiratory Infections - Cochrane for Clinicians - American ...

Feb 1, 2005 - Delayed prescribing appears to be a reasonable and safe option in patients with cough and in those who do not appear very ill, but it cannot be recommended for children with sore throat unless streptococcal pharyngitis has been ruled out. Delayed prescribing of antibiotics results in a ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0201/p466.html

Home Oxygen Therapy for Treatment of Patients with Chronic Obstructive Pulmonary ...

Sep 1, 2004 - There is good evidence that the addition of home long-term continuous oxygen therapy for COPD increases survival rates in patients with severe hypoxemia (i.e., O2 saturation of less than 90 percent or partial pressure of arterial oxygen [PaO2] of less than 8 kPa per 60 mm Hg) but not in...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0901/p864.html

Are Metered-Dose Inhalers with Holding Chambers Better Than Nebulizers for Treating ...

Jan 1, 2003 - In the emergency room, MDIs with holding chambers are as effective as nebulizers for delivering beta2 agonists to treat acute asthma in adults and children older than age two. There might be slightly less beta2 agonist–induced tachycardia in children when MDIs with holding chambers are ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0101/p62.html

Do Children with Acute Asthma Benefit More from Anticholinergics and Beta2 Agonists ...

Aug 1, 2002 - Children with moderate to severe asthma exacerbations experience improved respiratory function and are less likely to require hospital admission when treated with multiple doses of beta2 agonists combined with anticholinergics. The same benefit has not been proved in children with mild ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2002/0801/p417.html

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