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Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...

May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p545.html

Treatment of Threatened Miscarriage with Progestogens - Cochrane for Clinicians - ...

Sep 1, 2019 - Progestogens reduce the risk of miscarriage when compared with placebo in patients with threatened miscarriage (number needed to treat [NNT] = 10.) Use of progestogens poses no significant risks to mother or baby.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p279.html

Alternative Interventions for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Men -...

Jun 1, 2019 - In men with chronic pelvic pain and urinary dysfunction who have not responded to standard medical management, extracorporeal shock wave therapy reduces symptoms and increases quality of life. Acupuncture may also provide benefit to some patients.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p677.html

Complementary and Integrative Treatments for Pain Management in Labor - Cochrane for ...

Feb 1, 2019 - There is evidence that all of the studied interventions have some benefit in labor, but the evidence is of low to very low quality. Massage, thermal interventions (warm and cold packs), relaxation techniques, yoga, and music reduce pain during latent labor, but not during active labor.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0201/p154.html

Yoga for Cancer-Related Symptoms in Women with Breast Cancer - Cochrane for Clinicians ...

Oct 1, 2017 - Yoga improves health-related quality of life, reduces sleep disturbances, and decreases fatigue in the short term (up to 12 weeks) among women diagnosed with breast cancer who have completed cancer-related treatment or are receiving cancer treatment compared with no intervention.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/1001/p434.html

Preventing Unintended Adolescent Pregnancy - Cochrane for Clinicians - American Family ...

Apr 1, 2017 - Among adolescents, educational interventions increase reported condom use at most recent intercourse, whereas contraceptive-promoting interventions increase use of hormonal contraception.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0401/p422.html

Misoprostol for Incomplete First Trimester Miscarriage - Cochrane for Clinicians - ...

Apr 1, 2014 - Misoprostol, administered by various routes, is as effective as expectant management and nearly as effective as uterine aspiration. All three options have high success rates for completing miscarriage. Women treated with misoprostol had higher rates of nausea, prolonged bleeding, and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0401/p523.html

Oral Contraceptives Are Not an Effective Treatment for Ovarian Cysts - Cochrane for ...

Nov 1, 2014 - Oral contraceptives are not an effective treatment for ovarian cysts, whether the cysts are spontaneous or associated with medically induced ovulation. Most cysts resolve without intervention within two to three months. Those that do not resolve in this time frame are more likely to be ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/1101/p623.html

Calcium Supplementation for Preventing Hypertensive Disorders in Pregnancy - Cochrane ...

Oct 1, 2015 - High-dose calcium supplementation (i.e., at least 1,000 mg per day) during pregnancy reduces the risk of developing hypertension and preeclampsia. The most significant risk reduction occurs in women at risk of hypertensive disorders and those with low-calcium diets.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1001/p570.html

Magnesium Sulfate for Prevention of Preterm Birth - Cochrane for Clinicians - American ...

Apr 1, 2015 - Magnesium sulfate does not delay delivery when used in patients with preterm labor. Although magnesium sulfate is not associated with any serious adverse maternal outcomes, it may be associated with an increase in total fetal, neonatal, and infant mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0401/p444.html

Psychosocial and Psychological Interventions for Preventing Postpartum Depression - ...

Jun 1, 2014 - A range of prevention strategies can reduce the risk of postpartum depression, but more study is needed to determine which interventions are most effective.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0601/p871.html

Antenatal Perineal Massage to Prevent Birth Trauma - Cochrane for Clinicians - American...

Mar 1, 2014 - Antenatal digital perineal massage in the final month of pregnancy is safe and well tolerated. Women who have not had a previous vaginal delivery and perform digital perineal massage in the final month of pregnancy experience less perineal birth trauma, mostly through fewer ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0301/p335.html

Oxytocin Augmentation During Labor with Epidural Analgesia - Cochrane for Clinicians - ...

Jun 1, 2013 - Oxytocin augmentation does not reduce the frequency of cesarean delivery, instrumental vaginal delivery, or the combined outcome of both. Oxytocin also has no effect on low five-minute Apgar scores, postpartum hemorrhage, uterine hyperstimulation, or neonatal intensive care unit ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p760.html

Contraceptive Education for Women After Childbirth - Cochrane for Clinicians - American...

Jun 1, 2013 - Postpartum education may increase contraceptive use and reduce unplanned repeat pregnancies, although the evidence is mixed. The optimal timing and content of educational programs are not known.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p761.html

Vitamin D Supplementation for Women During Pregnancy - Cochrane for Clinicians - ...

Mar 1, 2013 - In several small, low-quality trials, vitamin D supplementation in pregnancy was associated with a statistically nonsignificant trend toward a decreased risk of low birth weight. There is insufficient evidence to recommend routine vitamin D supplementation in pregnancy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0301/p314.html

Epidural Analgesia for Labor Pain - Cochrane for Clinicians - American Family Physician

Aug 1, 2012 - Compared with other types of analgesia or no analgesia, epidurals offered better pain relief, but were associated with a longer second stage of labor and increased risk of instrumental vaginal delivery, maternal fever, and oxytocin (Pitocin) administration. There were no statistically ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0801/p241.html

Interventions to Increase Cervical Cancer Screening Rates - Cochrane for Clinicians - ...

Mar 1, 2012 - Invitation letters are the most studied method of encouraging cervical cancer screening, and they are effective (relative risk [RR] = 1.44; 95% confidence interval [CI], 1.24 to 1.52).1–3 Invitation letters may be more cost-effective than more intensive recruitment efforts (e.g., ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0301/p443.html

Exercise for Treatment of the Vasomotor Symptoms of Menopause - Cochrane for Clinicians...

Feb 1, 2012 - Although menopausal women who exercise are less likely to report vasomotor symptoms than those who do not, there is insufficient evidence that counseling women to exercise is more effective than no treatment or hormone therapy for vasomotor symptoms of menopause.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0201/p237.html

Instruments for Assisted Vaginal Delivery - Cochrane for Clinicians - American Family ...

Jul 1, 2011 - Use of forceps is more likely to result in a vaginal delivery than use of vacuum devices (relative risk [RR] = 1.5; 95% confidence interval [CI], 1.1 to 2.2), but has a higher rate of perineal trauma, tears, pain, and incontinence, and a trend toward more cesarean deliveries. Use of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0701/p26.html

Magnesium Sulfate and Other Anticonvulsants for Women with Preeclampsia - Cochrane for ...

Jun 1, 2011 - Magnesium sulfate should be considered first-line treatment to prevent eclamptic seizures during labor.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0601/p1269.html

Management Options for Early Incomplete Miscarriage - Cochrane for Clinicians - ...

Feb 1, 2011 - For the management of incomplete miscarriage, limited-quality evidence shows that medical treatment with misoprostol (Cytotec), expectant care, and surgical evacuation have a completion of miscarriage success rate between 80 to 99 percent in pregnancies at less than 13 weeks' ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0201/p258.html

Upright vs. Recumbent Maternal Position During First Stage of Labor - Cochrane for ...

Feb 1, 2010 - Upright positions include sitting, standing, walking, and kneeling. Based on heterogenous results, women who maintained upright positions had a first stage of labor that was about one hour less than women who were supine or reclined. There were no differences in type of delivery, and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0201/p285.html

Induction of Labor at or Beyond Term - Cochrane for Clinicians - American Family Physician

Sep 1, 2008 - Fetal or neonatal deaths in women who delivered after their due date and before 42 weeks occur at a rate of less than 0.5 percent, regardless of whether labor is induced or spontaneous. Compared with awaiting spontaneous labor, inducing labor between 41 and 42 weeks is associated with ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0901/p581.html

Cochrane for Clinicians - Oct 1, 2007 - American Family Physician

Oct 1, 2007 - Providing early opioid analgesia to patients presenting with acute abdominal pain does not affect or delay management decisions, but it lessens pain intensity as rated by the patient.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1001/p971.html

Cochrane for Clinicians - Oct 1, 2007 - American Family Physician

Oct 1, 2007 - There are no randomized controlled trials (RCTs) of labor induction in women with a low–transverse uterine scar. Observational studies indicate that there is a small increased risk of uterine rupture and adverse fetal outcomes, especially in women induced with prostaglandins. Although ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1001/p971a.html

Counseling Women About Mammography: Benefits vs. Harms - Cochrane for Clinicians - ...

Sep 1, 2007 - Studies of mammography show a 0.1 percent absolute reduction in breast cancer mortality with mammography. This means that if 2,000 women are offered mammography over 10 years, one woman would have her life prolonged, 10 healthy women would be treated unnecessarily for breast cancer, and...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0901/p652.html

Are Oral Betamimetics Effective Maintenance Therapies After Threatened Preterm Labor? -...

Mar 1, 2007 - There is no evidence to support the use of oral betamimetics for maintenance therapy after treatment for threatened preterm labor, and there is a risk of adverse effects with these drugs.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0301/p648.html

Expectant Management vs. Surgical Treatment for Miscarriage - Cochrane for Clinicians -...

Oct 1, 2006 - Expectant management and surgical treatment are safe and effective for first-trimester miscarriage. Among patients who choose expectant management, there is a lower rate of pelvic infection but higher rates of mild bleeding, need for unplanned surgical treatment, and incomplete ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1001/p1125.html

Cochrane for Clinicians - Jul 1, 2006 - American Family Physician

Jul 1, 2006 - Intravenous lidocaine and oral mexiletine provide a modest reduction in neuropathic pain with no indication of serious adverse effects. However, safety data are limited because most studies were of relatively short duration and fewer than 400 patients have been studied in total for each...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0701/p79.html

Cochrane for Clinicians - Jul 1, 2006 - American Family Physician

Jul 1, 2006 - Induction of labor in patients with PROM does not increase the rates of cesarean delivery or operative vaginal delivery. Among patients who are induced there is a slightly lower incidence of chorioamnionitis (relative risk [RR] 0.74; 95% confidence interval [CI], 0.56 to 0.97) and a ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0701/p79a.html

Cochrane for Clinicians - Apr 1, 2005 - American Family Physician

Apr 1, 2005 - For empiric treatment of GERD or endoscopy-negative reflux disease, a short trial of a proton pump inhibitor increases the chance of remission. Histamine H2-receptor antagonists are less expensive and work well in many patients, particularly those with less severe symptoms or ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0401/p1303a.html

Cochrane for Clinicians - Apr 1, 2005 - American Family Physician

Apr 1, 2005 - Based on three good studies of 462 patients, discontinuing epidural analgesia in the second stage of labor does not significantly change rates of instrumented delivery or other delivery outcomes, but it increases rates of inadequate pain relief.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0401/p1303.html

Cochrane for Clinicians - Mar 1, 2005 - American Family Physician

Mar 1, 2005 - Treatment with betamimetics decreases the number of women with preterm labor who give birth within 48 hours, but it does not decrease the number of births within seven days. Limited evidence suggests that treatment with beta-mimetics does not decrease perinatal death or morbidity.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p899a.html

Cochrane for Clinicians - Mar 1, 2005 - American Family Physician

Mar 1, 2005 - NPH insulin and metformin taken at bedtime appears to be the most favorable combination studied, but this conclusion is based on poor-quality, inconsistent studies that measure disease-oriented outcomes. There are no data on the effect of these drug combinations on patient-oriented ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p899.html

What Is the Best Collection Device for Screening Cervical Smears? - Cochrane for ...

Apr 1, 2004 - The combination of an extended-tip spatula with an endocervical brush (Cytobrush) is the most effective method for obtaining cervical cells. Detection of endocervical cells is a good indication of adequate smears and detection of disease.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0401/p1661.html

Vaginal Estrogen Preparations for Relief of Atrophic Vaginitis - Cochrane for ...

May 1, 2004 - Vaginal estrogen preparations are safe and effective as short-term treatment in patients with vaginal atrophy who are not candidates for systemic hormone therapy. Compared with estradiol products, conjugated equine estrogen creams may be associated with a higher incidence of adverse ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0501/p2111.html

Medical Methods for First-Trimester Abortion - Cochrane for Clinicians - American ...

Jul 1, 2004 - A regimen that includes mifepristone in a dosage of 200 mg administered orally, followed by misoprostol in a dosage of 800 mcg administered vaginally, is highly effective for medical abortion up to 63 days’ gestation. Side effects include bleeding, pain, nausea, vomiting, and diarrhea. ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0701/p81.html

Should We Offer Routine Breast Cancer Screening with Mammography? - Cochrane for ...

Jul 15, 2003 - While there is good evidence that mammography starting at age 50 reduces breast cancer mortality, this meta-analysis does not provide evidence of a mortality benefit for mammography screening in women aged 40 to 49. Controversy exists over whether to include in the analysis trials with ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0715/p260.html

Should Active Management of the Third Stage of Labor Be Routine? - Cochrane for ...

May 15, 2003 - Active management of the third stage of labor (i.e., administration of a uterotonic medication before the placenta is delivered, early clamping and cutting of the umbilical cord, and application of controlled traction to the cord) is associated with reduced maternal blood loss, fewer ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0515/p2119.html

Intensive Management of Gestational Diabetes - Cochrane for Clinicians - American ...

Jul 1, 2004 - Advertisement << Previous article Next article >> Jul 1, 2004 Issue Cochrane Briefs Am Fam Physician. 2004 Jul 1;70(1):84. Intensive Management of Gestational Diabetes Clinical Question Does intensive management of gestational diabetes improve outcomes? Evidence-Based Answer There is...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0701/p84.html

Caregiver Support for Women During Childbirth: Does the Presence of a Labor-Support ...

Oct 1, 2002 - This review indicates that continuous caregiver support during childbirth has a number of benefits with minimal to no risks. It was less likely that women would need pain medications or have an operative vaginal delivery, a cesarean section, or a five-minute Apgar score of less than 7 ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2002/1001/p1205.html

Screening for and Treating Asymptomatic Bacterial Vaginosis in Pregnancy - Cochrane for...

Sep 1, 2002 - No. Screening for and treating BV in pregnant women who are at low risk for preterm delivery does not lower the risk of preterm delivery. If this patient were at high risk for preterm delivery (i.e., a history of preterm delivery or underweight before pregnancy), it would be reasonable ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2002/0901/p780.html

What Is the Best Way to Treat Trichomoniasis in Women? - Cochrane for Clinicians - ...

Oct 1, 2001 - Nitroimidazoles (such as metronidazole [Flagyl]) are the most effective treatment for parasitological cure of trichomoniasis. Single-dose treatment is as effective as longer term treatment but increases side effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2001/1001/p1241.html

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