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AAP Releases Guideline on Managing Type 2 Diabetes Mellitus in Patients 10 to 18 Years ...

Nov 15, 2013 - Childhood type 2 diabetes poses a challenge to many physicians who are not used to treating this disease in such young patients. The American Academy of Pediatrics (AAP) has released a guideline of evidence-based recommendations for treating type 2 diabetes in patients 10 to 18 years of...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/1115/p710.html

Abaloparatide (Tymlos) for Osteoporosis - STEPS - American Family Physician

Feb 15, 2019 - Abaloparatide is a safe and effective medication used to reduce the likelihood of vertebral and nonvertebral fractures in women at high risk. However, it is expensive and requires daily injections. It has not been evaluated for its effect on decreasing hip fractures.

American Family Physician : STEPS

https://www.aafp.org/afp/2019/0215/p260.html

ACE Inhibitors vs. ARBs for Patients with Diabetic Kidney Disease - Cochrane for ...

Jul 1, 2007 - Studies comparing ACE inhibitors or ARBs with placebo found no mortality benefit in patients with diabetic kidney disease. A subgroup analysis of five studies (2,034 total patients) found that, when given at full or maximally tolerated doses, ACE inhibitors reduce all-cause mortality ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0701/p68.html

ACOG Releases Guidelines for Clinical Management of Osteoporosis - Practice Guidelines ...

Mar 15, 2004 - The American College of Obstetricians and Gynecologists (ACOG) recently issued guidelines for the clinical management of osteoporosis in women, including recommendations for screening, prevention, and treatment.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2004/0315/p1558.html

ACP Releases Guideline on Hormone Testing and Pharmacologic Treatment of Erectile ...

May 1, 2010 - As the general population ages and life expectancy increases, erectile dysfunction (ED) is anticipated to be a major health care burden. Therefore, the American College of Physicians (ACP) created a guideline on hormone testing and pharmacologic treatment of ED.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2010/0501/p1158.html

ACP Releases Guideline on Intensive Insulin Therapy in Hospitalized Patients - Practice...

Nov 1, 2011 - The American College of Physicians (ACP) has issued a clinical guideline on the use of intensive insulin therapy in hospitalized patients with or without diabetes mellitus to achieve glycemic control and improve health outcomes.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2011/1101/p1058.html

ACP Releases Guideline on Lipid Control in Patients with Type 2 Diabetes Mellitus - ...

Aug 15, 2004 - A guideline on the management of dyslipidemia, particularly hypercholesterolemia, in patients with type 2 diabetes mellitus has been published by the Clinical Efficacy Assessment Subcommittee of the American College of Physicians (ACP).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2004/0815/p775.html

ACP Releases Guideline on Treatment of Low Bone Mineral Density or Osteoporosis to ...

May 1, 2009 - The American College of Physicians (ACP) recently released guidelines on treatment of low bone mineral density (BMD) or osteoporosis to prevent fractures describes the available evidence on pharmacologic treatment in men and women.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2009/0501/p808.html

ACP Updates Guideline on Oral Pharmacologic Treatments for Type 2 Diabetes Mellitus - ...

Jan 15, 2013 - The American College of Physicians (ACP) has published an updated guideline on the oral pharmacologic management of type 2 diabetes. Recommendations are based on a systematic evidence review of head-to-head comparisons of oral pharmacologic treatments for type 2 diabetes, and an ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0115/p140.html

ADA Releases Standards of Medical Care for Patients with Diabetes - Practice Guidelines...

Sep 1, 2006 - The American Diabetes Association (ADA) has published a position statement containing evidence-based recommendations for diabetes care, treatment goals, and tools to evaluate the quality of care.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0901/p871.html

ADA Releases Updated Recommendations on Standards of Medical Care in Diabetes - ...

Jul 15, 2010 - The 2010 American Diabetes Association's (ADA) Standards of Medical Care in Diabetes includes revisions based on new evidence. Several sections have undergone major changes.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2010/0715/p206.html

Adding Sitagliptin Does Not Reduce or Increase the Risk of Cardiovascular Outcomes - ...

Dec 1, 2015 - The glass half full is that sitagliptin does not increase the risk of cardiovascular events in patients with type 2 diabetes. The glass half empty is that it does not reduce the risk, either. And that is the important message: In patients with a mean glycated hemoglobin level of 7.2%, ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/1201/p1020a.html

AHRQ Reviews Management of Gestational Diabetes - Practice Guidelines - American Family...

Nov 15, 2008 - The Agency for Healthcare Research and Quality (AHRQ) systematically reviewed the literature on the management of gestational diabetes. Gestational diabetes is one of the most common complications of pregnancy, affecting about 7 percent of pregnancies each year in the United States.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2008/1115/p1217.html

Albiglutide (Tanzeum) for Diabetes Mellitus - STEPS - American Family Physician

Apr 15, 2017 - Reductions in A1C are less with albiglutide than with the first-line therapy metformin, and albiglutide costs significantly more than metformin and sulfonylureas. Albiglutide's ability to reduce diabetes-related morbidity and major cardiovascular events is unknown.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0415/p521.html

Alternatives to Metformin for Patients with PCOS - FPIN's Help Desk Answers - American ...

Sep 1, 2016 - Compared with placebo, thiazolidinediones (TZDs) decrease systolic blood pressure and fasting blood glucose and insulin levels while improving menstrual irregularities in women with PCOS. Metformin and TZDs have similar effects on pregnancy rates, ovulation, and menstrual frequency, but...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0901/p378.html

Angiotensin Blockade in Patients with Diabetic Nephropathy - FPIN's Clinical Inquiries ...

Aug 1, 2007 - When used to delay the progression of early nephropathy in patients with type 2 diabetes mellitus, angiotensin receptor blockers (ARBs) are not superior to angiotensin-converting enzyme (ACE) inhibitors.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2007/0801/p423.html

Are Alpha-glucosidase Inhibitors Effective for Control of Type 2 Diabetes? - Cochrane ...

Feb 1, 2006 - The use of alpha-glucosidase inhibitors has a modest effect on intermediate diabetes-control endpoints such as postprandial blood glucose, postprandial insulin levels, and A1C levels. There is no evidence, however, of improvement in mortality, morbidity, or quality of life. In ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0201/p433.html

Are Long-acting Insulin Analogues Better Than Isophane Insulin? - Cochrane for ...

Feb 15, 2008 - Based on poor quality evidence, this review suggests that insulin glargine and insulin detemir have no advantage over isophane insulin in reducing A1C levels. In one study, isophane insulin reduced A1C levels slightly more than insulin detemir. However, patients on insulin glargine and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0215/p447.html

Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...

May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p545.html

Bariatric Surgery Improves Quality of Life and Results in More Weight Loss Than ...

Jun 15, 2017 - Bariatric surgery using Roux-en-Y gastric bypass or sleeve gastrectomy was more effective than intensive medical therapy at improving quality of life and helping patients lose weight and reduce the need for medications. Anemia was more common with sleeve gastrectomy, and approximately ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0615/p805.html

Becaplermin (Regranex) for Diabetic Foot Ulcers - STEPS - American Family Physician

Jul 15, 2008 - Although patients treated with becaplermin are more likely to experience complete and faster ulcer healing than patients continuing good wound care alone, the increased risk of cancer mortality and significant cost outweigh the possible benefits in most patients.

American Family Physician : STEPS

https://www.aafp.org/afp/2008/0715/p255.html

Bisphosphonate-Related Osteonecrosis of the Jaw in Patients with Osteoporosis - ...

Jun 15, 2012 - In 2007, more than 5.4 million patients in the United States were taking oral bisphosphonates. However, bisphosphonates are under scrutiny because of the risk of bisphosphonate-related osteonecrosis of the jaw.

American Family Physician : Editorials

https://www.aafp.org/afp/2012/0615/p1134.html

Blood Pressure Goal of 140 to 150 mm Hg Is Best for Patients with Diabetes - POEMs - ...

Jul 1, 2016 - Although most recent practice guidelines have relaxed the blood pressure goals for patients with diabetes, there are still a few holdouts that suggest aggressive treatment. This analysis shows that the ideal range for hypertension control in patients with diabetes is between 140 and 150...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0701/p59a.html

Brief Interventions for Weight Management in Kids Are Not Effective - POEMs - American ...

Feb 1, 2017 - Calculating the BMI of children and adolescents in primary care practices and counseling those who are overweight is ineffective to reduce BMI in children over several years of follow-up.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0201/p194a.html

Bromocriptine Mesylate (Cycloset) for Type 2 Diabetes Mellitus - STEPS - American ...

May 15, 2013 - Cycloset will lower A1C levels by 0.3 to 0.5 percent when taken alone or in combination with a sulfonylurea, without undesirable adverse effects such as hypoglycemia and weight gain. It will not cause further improvement of glucose control when used with insulin, metformin, or other ...

American Family Physician : STEPS

https://www.aafp.org/afp/2013/0515/p718.html

Choosing First-Line Therapy for Management of Type 2 Diabetes - AFP Journal Club - ...

Jan 1, 2008 - Which controls type 2 diabetes best at five years: rosiglitazone, metformin, or glyburide? Metformin should be the first-line drug for managing type 2 diabetes. Insulin and sulfonylureas should be second line, and glitazones should be reserved for third line.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2008/0101/p16.html

Cochrane for Clinicians - Dec 1, 2004 - American Family Physician

Dec 1, 2004 - Combined evidence from two clinical trials of calcium supplementation lasting for several years revealed a reduced rate of recurrent colorectal adenoma. However, evidence is insufficient to recommend supplementation with dietary calcium for patients who have never had an adenoma.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/1201/p2109.html

Cochrane for Clinicians - Mar 1, 2005 - American Family Physician

Mar 1, 2005 - NPH insulin and metformin taken at bedtime appears to be the most favorable combination studied, but this conclusion is based on poor-quality, inconsistent studies that measure disease-oriented outcomes. There are no data on the effect of these drug combinations on patient-oriented ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p899.html

Cochrane for Clinicians - Mar 1, 2005 - American Family Physician

Mar 1, 2005 - Treatment with betamimetics decreases the number of women with preterm labor who give birth within 48 hours, but it does not decrease the number of births within seven days. Limited evidence suggests that treatment with beta-mimetics does not decrease perinatal death or morbidity.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0301/p899a.html

Combination Therapy for Postmenopausal Osteoporosis - FPIN's Clinical Inquiries - ...

Feb 15, 2010 - There is insufficient evidence to recommend combination therapy for the routine management of postmenopausal osteoporosis.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2010/0215/p439.html

Combination Therapy for Type 2 Diabetes - Editorials - American Family Physician

Dec 1, 2001 - Advertisement << Previous article Next article >> Dec 1, 2001 Issue Editorials Combination Therapy for Type 2 Diabetes DAVID S. H. BELL, M.D. University of Alabama at Birmingham School of Medicine, Birmingham, Alabama Am Fam Physician. 2001 Dec 1;64(11):1812-1815. Until just over six...

American Family Physician : Editorials

https://www.aafp.org/afp/2001/1201/p1812.html

Controlling Hypertension in Patients with Diabetes - American Family Physician

Oct 1, 2002 - Hypertension and diabetes mellitus are common diseases in the United States. Patients with diabetes have a much higher rate of hypertension than would be expected in the general population. Regardless of the antihypertensive agent used, a reduction in blood pressure helps to prevent ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1001/p1209.html

Dapagliflozin (Farxiga) for Type 2 Diabetes Mellitus - STEPS - American Family Physician

Jun 15, 2015 - Dapagliflozin will lower A1C levels by an average of 0.7 percentage points when used alone or by an average of 0.5 percentage points when added to metformin therapy. Its effect on diabetes-associated morbidity and mortality has not been studied, and although it is well tolerated, there ...

American Family Physician : STEPS

https://www.aafp.org/afp/2015/0615/p828.html

Dapagliflozin in High-Risk Type 2 Diabetes Reduces Hospitalization for Heart Failure ...

Aug 1, 2019 - The only cardiovascular benefit to treatment with dapagliflozin was a reduction in the likelihood of hospitalization; 125 patients would need to be treated for 10 years to prevent one hospitalization.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0801/p184.html

Denosumab for Reducing Risk of Fractures in Postmenopausal Women - Medicine by the ...

May 1, 2019 - Denosumab appears to be effective in reducing the risk of vertebral and nonvertebral fractures in postmenopausal women with osteoporosis. Treatment with denosumab does not increase the risk of cancer or death but might increase the risk of infection. However, more studies are required.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0501/od1.html

Detrimental Effect of Tight Glucose Control on CV Mortality Persists Over Nine Years - ...

Mar 15, 2017 - The initial Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, which compared standard treatment with intensive control, found that despite good intentions, cardiovascular (CV) and overall mortality are significantly higher when blood glucose levels are lower.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0315/od2.html

Diabetes Education and Glycemic Control - FPIN's Clinical Inquiries - American Family ...

Feb 15, 2018 - Counseling by a diabetes educator or a team of educators delivered in a variety of formats may reduce A1C levels by 0.2% to 0.8% compared with usual care alone. Diabetes educators should be considered for patients who have higher baseline A1C levels (8% to 9%) because this group had ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/0215/p269.html

Diabetes Mellitus: Management of Gastrointestinal Complications - American Family ...

Dec 15, 2016 - Gastrointestinal disorders are common complications of diabetes mellitus and include gastroparesis, nonalcoholic fatty liver disease, gastroesophageal reflux disease, and chronic diarrhea. Symptoms of gastroparesis include early satiety, postprandial fullness, nausea, vomiting of ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1215/p980.html

Diabetes Self-Management: Facilitating Lifestyle Change - American Family Physician

Sep 15, 2017 - Healthy eating and increased physical activity can prevent or delay the onset of diabetes mellitus and facilitate diabetes management. Current guidelines recommend long-term weight loss of 5% to 7% of body weight and 150 minutes of at least moderate-intensity physical activity per week ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0915/p362.html

Diabetes: Foot Ulcers and Amputations - Clinical Evidence Handbook - American Family ...

Oct 15, 2009 - What are the effects of interventions to prevent foot ulcers and amputations in persons with diabetes? What are the effects of treatments in persons with diabetes with foot ulceration?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2009/1015/p789.html

Diabetes: Treating Hypertension - Clinical Evidence Handbook - American Family Physician

Apr 15, 2013 - What are the effects of antihypertensives and different blood pressure targets in persons with diabetes and hypertension?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/0415/p574.html

Diabetic Foot Infection - American Family Physician

Jul 1, 2008 - Foot infections are common in patients with diabetes and are associated with high morbidity and risk of lower extremity amputation. Diabetic foot infections are classified as mild, moderate, or severe. Gram-positive bacteria, such as Staphylococcus aureus and beta-hemolytic ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0701/p71.html

Diabetic Ketoacidosis - American Family Physician

May 1, 2005 - A diagnosis of diabetic ketoacidosis requires the patient's plasma glucose concentration to be above 250 mg per dL (although it usually is much higher), the pH level to be less than 7.30, and the bicarbonate level to be 18 mEq per L or less. Beta-hydroxybutyrate is a better measurement ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0501/p1705.html

Diabetic Ketoacidosis: Evaluation and Treatment - American Family Physician

Mar 1, 2013 - Diabetic ketoacidosis is characterized by a serum glucose level greater than 250 mg per dL, a pH less than 7.3, a serum bicarbonate level less than 18 mEq per L, an elevated serum ketone level, and dehydration. Insulin deficiency is the main precipitating factor. Diabetic ketoacidosis ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0301/p337.html

Diabetic Nephropathy - Clinical Evidence Handbook - American Family Physician

Dec 1, 2005 - What are the effects of treatments in persons with type 1 diabetes and early or late nephropathy? What are the effects of treatments in persons with type 2 diabetes and early or late nephropathy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2005/1201/p2299.html

Diabetic Nephropathy: Preventing Progression - Clinical Evidence Handbook - American ...

Mar 15, 2011 - What are the effects of treatments to prevent progression of nephropathy in persons with type 1 and type 2 diabetes and early and late nephropathy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2011/0315/p732.html

Diagnosis and Management of Gestational Diabetes Mellitus - American Family Physician

Jul 1, 2009 - Gestational diabetes occurs in 5 to 9 percent of pregnancies in the United States and is growing in prevalence. It is a controversial entity, with conflicting guidelines and treatment protocols. Recent studies show that diagnosis and management of this disorder have beneficial effects ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0701/p57.html

Dipeptidyl-peptidase-4 Inhibitors for Treatment of Type 2 Diabetes - Cochrane for ...

Mar 1, 2009 - When used as monotherapy or in conjunction with metformin (Glucophage) or thiazolidinediones, the DPP-4 inhibitor sitagliptin (Januvia) decreases A1C levels by 0.7 percent, but there are no data on patient-oriented outcomes or long-term safety. Until more studies are completed, it ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0301/p372.html

Does Metformin Improve Clinical Features of Polycystic Ovary Syndrome? - Cochrane for ...

Dec 1, 2003 - Metformin therapy improves fasting insulin levels and blood pressure. It has no clinically significant effect on body weight, waist:hip ratio, or LDL cholesterol level. Metformin, taken with or without clomiphene, appears to be an effective first-line agent for ovulation induction in ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/1201/p2163.html

Does Metformin Increase the Risk of Fatal or Nonfatal Lactic Acidosis? - Cochrane for ...

Nov 1, 2010 - In patients without standard contraindications to metformin therapy, metformin does not increase the risk of lactic acidosis.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/1101/p1068.html

Does Pioglitazone Benefit Patients With Type 2 Diabetes? - Cochrane for Clinicians - ...

Oct 1, 2007 - Pioglitazone produces a reduction in A1C levels similar to that produced by other drugs. One trial found that although pioglitazone, used as an adjunct to other antihyperglycemic medications, may lead to a statistically significant reduction in morbidity and mortality in patients with ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1001/p969.html

DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes...

Apr 1, 2018 - There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0401/p437.html

Dulaglutide (Trulicity) for Type 2 Diabetes Mellitus - STEPS - American Family Physician

Oct 15, 2017 - Dulaglutide is an easy-to-use, once-weekly injectable therapy for the treatment of type 2 diabetes in adults. It produces a modest decrease in A1C levels with only a small risk of severe hypoglycemia. The small average weight loss it induces may be an advantage for some patients.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/1015/p540.html

Duration of Bisphosphonate Therapy - FPIN's Help Desk Answers - American Family Physician

Apr 1, 2018 - Oral bisphosphonates significantly reduce clinical fracture risk at four years in women with postmenopausal osteoporosis (T-score less than −2.5). Treatment beyond five years is associated with further reductions in fractures in women with persistent femoral neck T-scores less than −2.5.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0401/od1.html

Editorials: Controversies in Family Medicine - Dec 15, 2012 - American Family Physician

Dec 15, 2012 - Yes: This Should Be the Target for Most Patients

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2012/1215/od1.html

Educational Guidelines for Achieving Tight Control and Minimizing Complications of Type...

Nov 1, 1999 - Tight glucose control with intensive therapy in patients with type 1 diabetes (formerly known as juvenile-onset or insulin-dependent diabetes) can delay the onset and slow the progression of retinopathy, nephropathy and neuropathy. Optimal blood glucose control is defined by a target ...

American Family Physician : Article

https://www.aafp.org/afp/1999/1101/p1985.html

Effectiveness of Insulin Sensitizing Drugs for Polycystic Ovary Syndrome - Cochrane for...

Nov 1, 2007 - Insulin sensitizing drugs are more effective than oral contraceptives alone at improving fasting insulin levels in patients with PCOS. Compared with metformin (Glucophage) alone, oral contraceptives alone better control irregular menstrual cycles and reduce androgen levels. There is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1101/p1308.html

Empagliflozin (Jardiance) for Type 2 Diabetes Mellitus - STEPS - American Family Physician

Dec 15, 2016 - Empagliflozin can be added to existing type 2 diabetes treatment to lower A1C levels, although there are less expensive options. In older patients with preexisting cardiovascular disease, empagliflozin can decrease all-cause mortality, cardiovascular mortality, and hospitalization for ...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/1215/p1014.html

Endocrine Society Releases Guidelines on Diagnosis and Management of ...

Jul 15, 2013 - The Endocrine Society recently published evidence-based recommendations on the diagnosis and management of hypertriglyceridemia in adults. Contributing factors include overweight and obesity, physical inactivity, excessive alcohol intake, metabolic syndrome, type 2 diabetes mellitus, ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0715/p142.html

Exenatide Injection (Byetta): Adjunctive Therapy for Glycemic Control - STEPS - ...

Jun 15, 2006 - Exenatide is an injectable treatment for type 2 diabetes. Its use requires patient education and strict monitoring of glucose levels because of the difficulty of its administration; therefore, it may not be a safe or practical option for patients who are not willing or able to ...

American Family Physician : STEPS

https://www.aafp.org/afp/2006/0615/p2213.html

Facilitating Treatment Adherence With Lifestyle Changes in Diabetes - American Family ...

Jan 15, 2004 - Healthy eating and increased physical activity can prevent or delay diabetes and its complications. Techniques that facilitate adherence to these lifestyle changes can be adapted to primary care. Often, the patient's readiness to work toward change must be developed gradually. To ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0115/p309.html

Fracture Prevention in Postmenopausal Women - Clinical Evidence Handbook - American ...

May 15, 2008 - What are the effects of treatments to prevent fractures in postmenopausal women?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2008/0515/p1447.html

Gender-Dysphoric/Gender-Incongruent Persons: Treatment Recommendations from the ...

May 1, 2018 - Gender-dysphoric/gender-incongruent persons require a safe and effective hormone regimen. These recommendations are an update to the clinical practice guideline on endocrine treatment of transsexual persons published in 2009 by the Endocrine Society.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/0501/p608.html

Glucose Control in Hospitalized Patients - American Family Physician

May 1, 2010 - Evidence indicates that hospitalized patients with hyperglycemia do not benefit from tight blood glucose control. Maintaining a blood glucose level of less than 180 mg per dL (9.99 mmol per L) will minimize symptoms of hyperglycemia and hypoglycemia without adversely affecting ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0501/p1121.html

Glucose Management in Hospitalized Patients - American Family Physician

Nov 15, 2017 - Glucose management in hospitalized patients poses challenges to physicians, including identifying blood glucose targets, judicious use of oral diabetes mellitus medications, and implementing appropriate insulin regimens. Uncontrolled blood glucose levels can lead to deleterious effects ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1115/p648.html

Glycemic Control in Hospitalized Patients Not in Intensive Care: Beyond Sliding-Scale ...

May 1, 2010 - Glycemic control in hospitalized patients who are not in intensive care remains unsatisfactory. Despite persistent expert recommendations urging its abandonment, the use of sliding-scale insulin remains pervasive in U.S. hospitals. Evidence for the effectiveness of sliding-scale insulin...

American Family Physician : Article

https://www.aafp.org/afp/2010/0501/p1130.html

Glycemic Control in Patients with Type 2 Diabetes - FPIN's Clinical Inquiries - ...

Apr 1, 2007 - There is no clearly superior oral agent for glycemic control in patients with type 2 diabetes.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2007/0401/p1051.html

Glycemic Control in the Hospital: What to Do When Experts Disagree - Editorials - ...

May 1, 2010 - Advertisement << Previous article Next article >> May 1, 2010 Issue Editorials Glycemic Control in the Hospital: What to Do When Experts Disagree PETER HAM, MD, Department of Family Medicine, University of Virginia, Charlottesville, Virginia Am Fam Physician. 2010 May...

American Family Physician : Editorials

https://www.aafp.org/afp/2010/0501/p1078.html

Glycemic Control in Type 2 Diabetes (Drug Treatments) - Clinical Evidence Handbook - ...

May 15, 2014 - What are the effects of blood glucose–lowering medications in adults with type 2 diabetes?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2014/0515/p820.html

Growth Hormone for Treatment of Idiopathic Short Stature in Children - FPIN's Help Desk...

Jul 1, 2015 - Advertisement << Previous article Next article >> Jul 1, 2015 Issue FPIN's Help Desk Answers Growth Hormone for Treatment of Idiopathic Short Stature in Children SUFIAN ZAYED, MD, and DIANE J. MADLON-KAY, MD, MS, University of Minnesota Medical Center, Smiley's Family Medicine...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2015/0701/p64.html

Gynecomastia - American Family Physician

Apr 1, 2012 - Gynecomastia is defined as benign proliferation of glandular breast tissue in men. Physiologic gynecomastia is common in newborns, adolescents, and older men. It is self-limited, but can be treated to minimize emotional distress and physical discomfort. Nonphysiologic gynecomastia may ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0401/p716.html

High-Dose vs. Standard-Dose Heparin for VTE Prophylaxis in Obese Patients - FPIN's Help...

Jun 1, 2018 - In most patients weighing more than 220 lb (100 kg), high-dose heparin prophylaxis (7,500 units subcutaneously three times per day) does not further reduce the risk of VTE compared with standard-dose heparin (5,000 units subcutaneously two or three times per day).

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0601/od2.html

Home Glucose Monitoring Offers No Benefit to Patients Not Using Insulin - POEMs - ...

Dec 15, 2017 - Home glucose monitoring of patients in primary care does not improve A1C scores or quality of life over one year in patients who are not taking insulin.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/1215/od4.html

Home Monitoring of Glucose and Blood Pressure - American Family Physician

Jul 15, 2007 - Home monitoring of blood glucose and blood pressure levels can provide patients and physicians with valuable information in the management of diabetes mellitus and hypertension. Home monitoring allows patients to play an active role in their care and may improve treatment adherence and ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0715/p255.html

Hyperglycemic Crises: Improving Prevention and Management - Editorials - American ...

May 1, 2005 - Advertisement << Previous article Next article >> May 1, 2005 Issue Editorials Hyperglycemic Crises: Improving Prevention and Management ABBAS E. KITABCHI, PH.D., M.D.,University of Tennessee Health Science Center,Memphis,Tennessee Am Fam Physician. 2005 May 1;71(9):1659-1660. See...

American Family Physician : Editorials

https://www.aafp.org/afp/2005/0501/p1659.html

Hyperhidrosis: Management Options - American Family Physician

Jun 1, 2018 - Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0601/p729.html

Hyperosmolar Hyperglycemic State - American Family Physician

Dec 1, 2017 - Hyperosmolar hyperglycemic state is a life-threatening emergency manifested by marked elevation of blood glucose and hyperosmolarity with little or no ketosis. Although there are multiple precipitating causes, underlying infections are the most common. Other causes include certain ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1201/p729.html

Hyperosmolar Hyperglycemic State - American Family Physician

May 1, 2005 - Hyperosmolar hyperglycemic state is a life-threatening emergency manifested by marked elevation of blood glucose, hyperosmolarity, and little or no ketosis. With the dramatic increase in the prevalence of type 2 diabetes and the aging population, this condition may be encountered more ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0501/p1723.html

Hypertension and Diabetes: Family Physicians' Pivotal Role - Editorials - American ...

Oct 1, 2002 - Advertisement << Previous article Next article >> Oct 1, 2002 Issue Editorials Hypertension and Diabetes: Family Physicians' Pivotal Role GEORGE L. BAKRIS, M.D. Rush Presbyterian/St. Luke's Medical Center Chicago, Illinois Am Fam Physician. 2002 Oct 1;66(7):1151-1153. Related...

American Family Physician : Editorials

https://www.aafp.org/afp/2002/1001/p1151.html

Hyperthyroidism - Clinical Evidence Handbook - American Family Physician

Oct 1, 2007 - What are the effects of drug treatments for primary hyperthyroidism? What are the effects of treatments for subclinical hyperthyroidism?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2007/1001/p1014.html

Ibandronate (Boniva) for Treatment and Prevention of Osteoporosis in Postmenopausal ...

Jan 15, 2006 - Ibandronate is a bisphosphonate that can be taken daily or monthly. The daily dosage has been shown to decrease vertebral fractures in women with osteoporosis and a history of previous vertebral fractures. Neither formulation has been shown to reduce the risk of hip fracture or other ...

American Family Physician : STEPS

https://www.aafp.org/afp/2006/0115/p305.html

IDSA Releases Guidelines on the Diagnosis and Treatment of Diabetic Foot Infections - ...

Apr 1, 2005 - Guidelines for the diagnosis and treatment of diabetic foot infections have been developed by the Infectious Diseases Society of America (IDSA). In persons with diabetes, foot infections can cause substantial morbidity and are the most common nontraumatic cause of amputations.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2005/0401/p1429.html

Individualizing Target Goals and Treatment in Patients with Type 2 Diabetes - POEMs - ...

Jun 1, 2015 - This statement from American and European diabetes societies suggests that tighter control of hyperglycemia be attempted only in patients with a recent diagnosis and a low risk of hypoglycemia; who have a long life expectancy with few or no comorbidities, including cardiovascular ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0601/p788.html

Insulin Detemir (Levmir) for Diabetes Mellitus - STEPS - American Family Physician

Jul 15, 2006 - Insulin detemir is suitable as basal insulin in a basal-bolus regimen. In limited research, it has been shown to cause slightly fewer episodes of minor hypoglycemia and no weight gain in patients with type 1 and 2 diabetes, which is a benefit that must be balanced against its higher ...

American Family Physician : STEPS

https://www.aafp.org/afp/2006/0715/p323.html

Insulin for Glycemic Control in Acute Ischemic Stroke - Cochrane for Clinicians - ...

Dec 1, 2012 - Administering insulin to maintain glycemic control does not improve the rates of mortality or dependency, or the final neurologic outcome after an acute ischemic stroke. Additionally, in randomized controlled trials, patients in the intervention groups (those under tight glycemic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1201/p1008.html

Insulin Inhalation Powder (Exubera) for Diabetes Mellitus - STEPS - American Family ...

May 15, 2007 - Inhaled insulin provides an alternative route of administration for rapid-acting insulin but offers no other benefit over available insulin therapy. It may reduce, but not eliminate, the need for self-injection in patients with type 1 diabetes. In patients with type 2 diabetes, the risk...

American Family Physician : STEPS

https://www.aafp.org/afp/2007/0515/p1546.html

Insulin Lispro: A Fast-Acting Insulin Analog - American Family Physician

Jan 15, 1998 - Research has established the importance of maintaining blood glucose levels near normal in patients with type 1 (insulin-dependent) diabetes mellitus. Short-acting insulin analogs are designed to overcome the limitations of regular short-acting insulins. Compared with regular human ...

American Family Physician : Article

https://www.aafp.org/afp/1998/0115/p279.html

Insulin Management of Type 2 Diabetes Mellitus - American Family Physician

Jul 15, 2011 - Insulin therapy is recommended for patients with type 2 diabetes mellitus and an initial A1C level greater than 9 percent, or if diabetes is uncontrolled despite optimal oral glycemic therapy. Insulin therapy may be initiated as augmentation, starting at 0.3 unit per kg, or as ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0715/p183.html

Insulin Therapy for Type 2 Diabetes: Rescue, Augmentation, and Replacement of Beta-Cell...

Aug 1, 2004 - Type 2 diabetes is characterized by progressive beta-cell failure. Indications for exogenous insulin therapy in patients with this condition include acute illness or surgery, pregnancy, glucose toxicity, contraindications to or failure to achieve goals with oral antidiabetic ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0801/p489.html

Intensive Lifestyle Intervention Fails to Improve Patient-Oriented Outcomes in Persons ...

Dec 15, 2013 - This large, well-designed trial failed to find a statistically significant improvement in patient-oriented outcomes in patients with diabetes, despite a fairly intensive lifestyle intervention and long-term follow-up.

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1215/od1.html

Intensive Management of Gestational Diabetes - Cochrane for Clinicians - American ...

Jul 1, 2004 - Advertisement << Previous article Next article >> Jul 1, 2004 Issue Cochrane Briefs Am Fam Physician. 2004 Jul 1;70(1):84. Intensive Management of Gestational Diabetes Clinical Question Does intensive management of gestational diabetes improve outcomes? Evidence-Based Answer There is...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0701/p84.html

Joint Guideline on Intensive Glycemic Control and the Prevention of Cardiovascular ...

Nov 15, 2009 - Recommendations from the American Diabetes Association (ADA), American College of Cardiology Foundation (ACC), and American Heart Association (AHA) for glycemic control and prevention of cardiovascular events in patients with diabetes.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2009/1115/p1167.html

Lending a Hand to Patients with Type 2 Diabetes: A Simple Way to Communicate Treatment ...

Feb 15, 2014 - A new approach to the care of adults with type 2 diabetes emphasizes proven interventions that improve duration and quality of life.

American Family Physician : Editorials

https://www.aafp.org/afp/2014/0215/p256.html

Linagliptin (Tradjenta) for the Treatment of Diabetes Mellitus - STEPS - American ...

Dec 15, 2012 - Linagliptin reduces A1C levels to a lesser extent than first-line therapy (metformin) and is significantly more expensive than metformin and sulfonylureas. Importantly, its ability to affect diabetes-related morbidity and mortality is not known.

American Family Physician : STEPS

https://www.aafp.org/afp/2012/1215/p1144.html

Lixisenatide (Adlyxin) for Type 2 Diabetes Mellitus - STEPS - American Family Physician

Aug 15, 2017 - ixisenatide is an easy-to-use, once-daily injectable therapy for the treatment of type 2 diabetes in adults. It is at least as effective as exenatide at reducing A1C and body weight, with similar rates of gastrointestinal adverse effects.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0815/p257.html

Long-Term Results of Drug Treatment for Obesity - POEMs - American Family Physician

Mar 1, 2014 - This review of commonly used weight-loss medications, including orlistat (Xenical), lorcaserin (Belviq), phentermine/topiramate (Qsymia), bupropion (Wellbutrin), metformin (Glucophage), and zonisamide (Zonegran), reported an average weight loss for participants of 2.5 to 8.0 kg (5.5 to ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0301/p389a.html

Long-Term Use of Bisphosphonates Increases the Risk of Fractures in Older Women - POEMs...

Jan 1, 2018 - In this cohort study, older women at a high risk of fractures who used oral bisphosphonates for 10 to 13 years had a higher risk of fractures than women who used bisphosphonates for only two years.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0101/p53a.html

Low Glycemic Index Diets for the Management of Diabetes - Cochrane for Clinicians - ...

Nov 1, 2009 - The low glycemic index diet (sometimes called a low glycemic load diet) lowered the A1C level by a weighted mean difference of 0.5 percent when compared with a high glycemic index (or glycemic load) diet. Fewer episodes of hypoglycemia occurred with a low glycemic index diet compared ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/1101/p941.html

Management of Blood Glucose in Type 2 Diabetes Mellitus - American Family Physician

Jan 1, 2009 - Evidence-based guidelines for the treatment of type 2 diabetes mellitus focus on three areas: intensive lifestyle intervention that includes at least 150 minutes per week of physical activity, weight loss with an initial goal of 7 percent of baseline weight, and a low-fat, ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0101/p29.html

Management of Blood Glucose with Noninsulin Therapies in Type 2 Diabetes - American ...

Jul 1, 2015 - A comprehensive, collaborative approach is necessary for optimal treatment of patients with type 2 diabetes mellitus. Treatment guidelines focus on nutrition, exercise, and pharmacologic therapies to prevent and manage complications. Patients with prediabetes or new-onset diabetes ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0701/p27.html

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