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Lymphoma: Diagnosis and Treatment - American Family Physician

Jan 1, 2020 - Lymphoma is a group of malignant neoplasms of lymphocytes with more than 90 subtypes. It is traditionally classified broadly as non-Hodgkin or Hodgkin lymphoma. Approximately 82,000 new U.S. patients are diagnosed with lymphoma annually. Any tobacco use and obesity are major modifiable ...

American Family Physician : Article

https://www.aafp.org/afp/2020/0101/p34.html

Colorectal Cancer Screening and Surveillance - American Family Physician

Jan 15, 2015 - Colorectal cancer is the third most common cancer in men and women. The incidence and mortality rate of the disease have been declining over the past two decades because of early detection and treatment. Screening in persons at average risk should begin at 50 years of age; the U.S. ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0115/p93.html

Multiple Myeloma: Diagnosis and Treatment - American Family Physician

Mar 15, 2017 - Multiple myeloma accounts for 1.6% of all cancer cases and approximately 10% of hematologic malignancies in the United States. In 2015, an estimated 28,850 new cases of multiple myeloma were diagnosed in the United States, and the disease caused more than 11,000 deaths. Patients older ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0315/p373.html

Cervical Cancer Screening - American Family Physician

Apr 1, 2018 - Screening in women has decreased the incidence and mortality of cervical cancer. Precancerous cervical lesions (cervical intraepithelial neoplasias) and cervical carcinomas are strongly associated with sexually-transmitted high-risk human papillomavirus (HPV) infection, which causes ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p441.html

Colorectal Cancer Screening and Prevention - American Family Physician

May 15, 2018 - Colorectal cancer is a common cause of morbidity and mortality in the United States. Most colorectal cancers arise from preexisting adenomatous or serrated polyps. The incidence and mortality of colorectal cancer can be reduced with screening of average-risk adults 50 to 75 years of ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0515/p658.html

Renal Cell Carcinoma: Diagnosis and Management - American Family Physician

Feb 1, 2019 - Kidney cancer is one of the 10 most common cancers in the United States with 90% being attributed to renal cell carcinoma. Men, especially black men, are more likely to be affected than women. Renal masses, either cystic or solid, are best detected with contrast-enhanced, triple-phase ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0201/p179.html

Bone Cancer: Diagnosis and Treatment Principles - American Family Physician

Aug 15, 2018 - Primary bone cancers include osteosarcoma, Ewing sarcoma, and chondrosarcoma. They account for less than 1% of diagnosed cancers each year and are associated with significant morbidity and mortality. Timely diagnosis is challenging because of late patient presentation, nonspecific ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0815/p205.html

Diagnosis and Management of Ovarian Cancer - American Family Physician

Jun 1, 2016 - Ovarian cancer is the most lethal gynecologic cancer. Less than one-half of patients survive for more than five years after diagnosis. Ovarian cancer affects women of all ages but is most commonly diagnosed after menopause. More than 75% of affected women are diagnosed at an advanced ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0601/p937.html

Localized Prostate Cancer: Treatment Options - American Family Physician

Jun 15, 2018 - In the United States, prostate cancer will be diagnosed in one out of seven men in his lifetime. Most cases are localized, and only one in 39 men will die from the disease. Prostate cancer is most often detected using serum prostate-specific antigen testing. The National Comprehensive ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0615/p798.html

Testicular Cancer: Diagnosis and Treatment - American Family Physician

Feb 15, 2018 - Testicular cancer is the most common solid tumor among males 15 to 34 years of age, with an estimated 8,850 new cases and 410 deaths during 2017 in the United States. With effective treatment, the overall five-year survival rate is 97%. Risk factors for testicular cancer include ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0215/p261.html

Bladder Cancer: Diagnosis and Treatment - American Family Physician

Oct 15, 2017 - Bladder cancer is the sixth most prevalent malignancy in the United States and causes more than 16,000 deaths annually. The most common clinical presentation is asymptomatic hematuria, which should prompt evaluation with cystoscopy, renal function testing, and upper urinary tract ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1015/p507.html

Diagnosis and Management of Adnexal Masses - American Family Physician

Apr 15, 2016 - Adnexal masses can have gynecologic or nongynecologic etiologies, ranging from normal luteal cysts to ovarian cancer to bowel abscesses. Women who report abdominal or pelvic pain, increased abdominal size or bloating, difficulty eating, or rapid satiety that occurs more than 12 times ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0415/p676.html

Primary Brain Tumors in Adults: Diagnosis and Treatment - American Family Physician

Feb 1, 2016 - Primary intracranial tumors of the brain structures, including meninges, are rare with an overall five-year survival rate of 33.4%; they are collectively called primary brain tumors. Proven risk factors for these tumors include certain genetic syndromes and exposure to high-dose ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0201/p211.html

Leukemia: An Overview for Primary Care - American Family Physician

May 1, 2014 - Leukemia is a clonal proliferation of hematopoietic stem cells in the bone marrow. The four broad subtypes most likely to be encountered by primary care physicians are acute lymphoblastic, acute myelogenous, chronic lymphocytic, and chronic myelogenous. Acute lymphoblastic leukemia ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0501/p731.html

Diagnosis and Management of Endometrial Cancer - American Family Physician

Mar 15, 2016 - Endometrial cancer is the most common gynecologic malignancy. It is the fourth most common cancer in women in the United States after breast, lung, and colorectal cancers. Risk factors are related to excessive unopposed exposure of the endometrium to estrogen, including unopposed ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0315/p468.html

Esophageal Cancer - American Family Physician

Jan 1, 2017 - Esophageal cancer has a poor prognosis and high mortality rate, with an estimated 16,910 new cases and 15,910 deaths projected in 2016 in the United States. Squamous cell carcinoma and adenocarcinoma account for more than 95% of esophageal cancers. Squamous cell carcinoma is more common...

American Family Physician : Article

https://www.aafp.org/afp/2017/0101/p22.html

Lung Cancer: Diagnosis, Treatment Principles, and Screening - American Family Physician

Feb 15, 2015 - Lung cancer is classified histologically into small cell and non–small cell lung cancers. The most common symptoms of lung cancer are cough, dyspnea, hemoptysis, and systemic symptoms such as weight loss and anorexia. High-risk patients who present with symptoms should undergo chest ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0215/p250.html

Cancer Screening in Older Patients - American Family Physician

Apr 15, 2016 - Although cancer is the second leading cause of death among persons 65 years and older, there is a paucity of clinical trial data about the effectiveness and harms of cancer screening in this population. Given the heterogeneous nature of the older population, cancer screening in these ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0415/p659.html

Primary Care of the Prostate Cancer Survivor - American Family Physician

May 1, 2016 - This summary of the American Cancer Society Prostate Cancer Survivorship Care Guidelines targets primary care physicians who coordinate care of prostate cancer survivors with subspecialists. Prostate cancer survivors should undergo prostate-specific antigen screening every six to 12 ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0501/p764.html

Diagnosis and Management of Pancreatic Cancer - American Family Physician

Apr 15, 2014 - Pancreatic cancer remains the fourth leading cause of cancer-related deaths in the United States. Risk factors include family history, smoking, chronic pancreatitis, obesity, diabetes mellitus, heavy alcohol use, and possible dietary factors. Because more than two-thirds of ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0415/p626.html

Common Questions About Barrett Esophagus - American Family Physician

Jan 15, 2014 - Barrett esophagus is a precancerous metaplasia of the esophagus that is more common in patients with chronic reflux symptoms, although it also occurs in patients without symptomatic reflux. Other risk factors include smoking, male sex, obesity, white race, hiatal hernia, and increasing ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0115/p92.html

Managing the Adverse Effects of Radiation Therapy - American Family Physician

Aug 15, 2010 - Nearly two thirds of patients with cancer will undergo radiation therapy as part of their treatment plan. Given the increased use of radiation therapy and the growing number of cancer survivors, family physicians will increasingly care for patients experiencing adverse effects of ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0815/p381.html

Cutaneous Malignant Melanoma: A Primary Care Perspective - American Family Physician

Jan 15, 2012 - Cutaneous malignant melanoma accounts for 3 to 5 percent of all skin cancers and is responsible for approximately 75 percent of all deaths from skin cancer. Persons with an increased number of moles, dysplastic (also called atypical) nevi, or a family history of the disease are at ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0115/p161.html

Treatment Options for Localized Prostate Cancer - American Family Physician

Aug 15, 2011 - In the United States, more than 90 percent of prostate cancers are detected by serum prostate-specific antigen testing. Most patients are found to have localized prostate cancer, and most of these patients undergo surgery or radiotherapy. However, many patients have low-risk cancer and ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0815/p413.html

Diagnosis and Treatment of Bladder Cancer - American Family Physician

Oct 1, 2009 - Bladder cancer is the sixth most prevalent malignancy in the United States. The most common type of bladder cancer is urothelial (transitional cell) carcinoma, and cystoscopy remains the mainstay of diagnosis and surveillance. Fluorescence cystoscopy offers improvement in the detection ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1001/p717.html

Treatment of Breast Cancer - American Family Physician

Jun 1, 2010 - Understanding breast cancer treatment options can help family physicians care for their patients during and after cancer treatment. This article reviews typical treatments based on stage, histology, and biomarkers. Lobular carcinoma in situ does not require treatment. Ductal carcinoma ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0601/p1339.html

Update on ASCCP Consensus Guidelines for Abnormal Cervical Screening Tests and Cervical...

Jul 15, 2009 - New data have emerged since publication of the American Society for Colposcopy and Cervical Pathology's 2001 consensus guidelines for management of abnormal cervical cytology and histology. The 2006 guidelines include recommendations for special populations (i.e., adolescents and ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0715/p147.html

Endometrial Cancer - American Family Physician

Nov 15, 2009 - Endometrial cancer is the leading cause of gynecologic cancer in the United States. Etiologically, endometrial carcinoma usually results from unopposed estrogen stimulation of the endometrium, although non-estrogen-related forms occur as well. The most common presentation of endometrial...

American Family Physician : Article

https://www.aafp.org/afp/2009/1115/p1075.html

Lymphadenopathy and Malignancy - American Family Physician

Dec 1, 2002 - The majority of patients presenting with peripheral lymphadenopathy have easily identifiable causes that are benign or self-limited. Among primary care patients presenting with lymphadenopathy, the prevalence of malignancy has been estimated to be as low as 1.1 percent. The critical ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1201/p2103.html

Primary Care of Adult Survivors of Childhood Cancer - American Family Physician

May 15, 2010 - There are approximately 300,000 survivors of childhood cancer in the United States, and most of them receive their medical care from primary care physicians. Adult survivors of childhood cancer are at considerable risk of long-term morbidity and mortality beyond the recurrence of their ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0515/p1250.html

Multiple Myeloma: Diagnosis and Treatment - American Family Physician

Oct 1, 2008 - Multiple myeloma, the most common bone malignancy, is occurring with increasing frequency in older persons. Typical symptoms are bone pain, malaise, anemia, renal insufficiency, and hypercalcemia. Incidental discovery on comprehensive laboratory panels is common. The disease is ...

American Family Physician : Article

https://www.aafp.org/afp/2008/1001/p853.html

Recognizing Neoplastic Skin Lesions: A Photo Guide - American Family Physician

Sep 15, 1998 - Malignant lesions of the skin are common. Patients who develop squamous cell carcinoma and malignant melanoma often have recognizable precursor conditions. A few skin lesions resemble malignancies. Lesions that are growing, spreading or pigmented, or those that occur on exposed areas of...

American Family Physician : Article

https://www.aafp.org/afp/1998/0915/p873.html

Ovarian Cancer: An Overview - American Family Physician

Sep 15, 2009 - Although ovarian cancer may occur at any age, it is more common in patients older than 50 years. Patients often present with nonspecific pelvic or abdominal symptoms. Initial diagnostic tests include transvaginal ultrasonography and serum cancer antigen 125 measurement; however, these ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0915/p609.html

Recent Advances in Radiation Therapy - American Family Physician

Dec 1, 2008 - Recent advances have improved the effectiveness, decreased the complications, and expanded the implications of radiation therapy. These advances include three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, stereotactic radiotherapy, brachytherapy, and ...

American Family Physician : Article

https://www.aafp.org/afp/2008/1201/p1254.html

Colonoscopy Surveillance After Polypectomy and Colorectal Cancer Resection - American ...

Apr 1, 2008 - This article describes a joint update of guidelines by the American Cancer Society and the U.S. Multi-Society Task Force on Colorectal Cancer delineating evidence-based surveillance recommendations for patients after polypectomy and colorectal cancer resection. Although there are some ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0401/p995.html

Colorectal Cancer: A Summary of the Evidence for Screening and Prevention - American ...

Dec 15, 2008 - Colorectal cancer causes significant morbidity and mortality in the United States. The incidence of colorectal cancer can be reduced with increasing efforts directed at mass screening of average-risk adults 50 years and older. Currently, fecal occult blood test and flexible ...

American Family Physician : Article

https://www.aafp.org/afp/2008/1215/p1385.html

Role of the Primary Care Physician in Hodgkin Lymphoma - American Family Physician

Sep 1, 2008 - Approximately 8,200 new cases of Hodgkin lymphoma are diagnosed annually in the United States. Common presenting features include painless lymphadenopathy (usually above the diaphragm), cough, fever, night sweats, and weight loss. To decrease late complications, treatment has gradually ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0901/p615.html

Cancer Screening in the Older Patient - American Family Physician

Dec 15, 2008 - Although there are clear guidelines that advise at what age to begin screening for various cancers, there is less guidance concerning when it may be appropriate to stop screening. The decision to stop screening must take into account patients' age; overall health and life expectancy; ...

American Family Physician : Article

https://www.aafp.org/afp/2008/1215/p1369.html

Lifestyle Interventions to Reduce Cancer Risk and Improve Outcomes - American Family ...

Jun 1, 2008 - There are more than one half million cancer deaths in the United States each year, and one third of these deaths are attributed to suboptimal diet and physical activity practices. Maintaining a healthy weight, staying physically active throughout life, and consuming a healthy diet can ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0601/p1573.html

Diagnosis and Treatment of Testicular Cancer - American Family Physician

Feb 15, 2008 - Testicular cancer is the most common malignancy in men 20 to 35 years of age and has an annual incidence of four per 100,000. If diagnosed early, the cure rate is nearly 99 percent. Risk factors for testicular cancer include cryptorchidism (i.e., undescended testicles), family history, ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0215/p469.html

Metastatic Carcinoma of the Long Bones - American Family Physician

Nov 15, 2007 - Breast, prostate, renal, thyroid, and lung carcinomas commonly metastasize to bone. Managing skeletal metastatic disease can be complex. Pain is the most common presenting symptom and requires thorough radiographic and laboratory evaluation. If plain-film radiography is not sufficient ...

American Family Physician : Article

https://www.aafp.org/afp/2007/1115/p1489.html

Esophageal Cancer: A Review and Update - American Family Physician

Jun 15, 2006 - Although significant advancements have been made in the treatment of esophageal cancer, this aggressive malignancy commonly presents as locally advanced disease with a poor prognosis. Despite improvements in the detection of premalignant pathology, newer preventative strategies, and the...

American Family Physician : Article

https://www.aafp.org/afp/2006/0615/p2187.html

Lung Cancer: Diagnosis and Management - American Family Physician

Jan 1, 2007 - Lung cancer is the leading cause of cancer-related death in the United States, with an average five-year survival rate of 15 percent. Smoking remains the predominant risk factor for lung cancer. Lung cancers are categorized as small cell carcinoma or non-small cell carcinoma (e.g., ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0101/p56.html

Management of Histologic Abnormalities of the Cervix - American Family Physician

Jan 1, 2006 - The American Society for Colposcopy and Cervical Pathology sponsored a consensus conference in 2001 to develop evidence-based guidelines for women with histologic abnormalities of the cervix. The options for management of cervical intraepithelial neoplasia 1, 2, and 3 are ranked ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0101/p105.html

Gastric Cancer: Diagnosis and Treatment Options - American Family Physician

Mar 1, 2004 - Although the overall incidence of gastric cancer has steadily declined in the United States, it is estimated that more than 12,000 persons died from gastric cancer in 2003. The incidence of distal stomach tumors has greatly declined, but reported cases of proximal gastric carcinomas, ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0301/p1133.html

Treatment Options for Prostate Cancer: Evaluating the Evidence - American Family Physician

May 15, 2005 - Controversy surrounds the management options for localized prostate cancer-conservative management, prostatectomy, and radiation. Choosing among these options is difficult because of long-term side effects that include sexual, urinary, and bowel dysfunction. Some recent studies suggest ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0515/p1915.html

Care of Cancer Survivors - American Family Physician

Feb 15, 2005 - Cancer survivors are at increased risk for recurrence of their original malignancy; development of second primary malignancies; and medical, developmental, and psychologic problems resulting from cancer therapy, genetic predisposition to cancer, and other risk factors. Surveillance ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0215/p699.html

Diethylstilbestrol Exposure - American Family Physician

May 15, 2004 - Diethylstilbestrol is a synthetic nonsteroidal estrogen that was used to prevent miscarriage and other pregnancy complications between 1938 and 1971 in the United States. In 1971, the U.S. Food and Drug Administration issued a warning about the use of diethylstilbestrol during pregnancy...

American Family Physician : Article

https://www.aafp.org/afp/2004/0515/p2395.html

Evaluation and Management of the AGUS Papanicolaou Smear - American Family Physician

Jun 1, 2001 - Atypical glandular cells on Papanicolaou smears are an unusual but important cytologic diagnosis. The Bethesda system classifies atypical glandular cells of undetermined significance (AGUS) as glandular cells that demonstrate nuclear atypia appearing to exceed reactive or reparative ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0601/p2239.html

Early Detection and Treatment of Skin Cancer - American Family Physician

Jul 15, 2000 - The incidence of skin cancer is increasing by epidemic proportions. Basal cell cancer remains the most common skin neoplasm, and simple excision is generally curative. Squamous cell cancers may be preceded by actinic keratoses-premalignant lesions that are treated with cryotherapy, ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0715/p357.html

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