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Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...

May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p545.html

Prophylactic Vaccination Against Human Papillomavirus to Prevent Cervical Cancer and ...

Jan 1, 2019 - HPV vaccination in women 15 to 26 years of age prevents the development of cervical intraepithelial neoplasia (CIN) 2 and CIN 3 in women regardless of previous HPV exposure (number needed to treat [NNT] = 39). No serious adverse effects are associated with administration of the HPV ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0101/p15.html

Surgery vs. Medical Therapy for Heavy Menstrual Bleeding - Cochrane for Clinicians - ...

Jul 1, 2017 - In women of reproductive age with chronic heavy menstrual bleeding, hysterectomy is the most effective treatment for controlling symptoms. Conservative surgery is more effective for controlling bleeding symptoms at one and two years than oral medications or the levonorgestrel-releasing ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0701/p24.html

Misoprostol for Incomplete First Trimester Miscarriage - Cochrane for Clinicians - ...

Apr 1, 2014 - Misoprostol, administered by various routes, is as effective as expectant management and nearly as effective as uterine aspiration. All three options have high success rates for completing miscarriage. Women treated with misoprostol had higher rates of nausea, prolonged bleeding, and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0401/p523.html

The Risk of MI and Ischemic Stroke with Combined Oral Contraceptives - Cochrane for ...

Nov 1, 2016 - The overall risk of MI and ischemic stroke is increased in women who use combined oral contraceptives. The relative risk of MI and ischemic stroke increases as estrogen dose rises, increasing by 60% with doses of 20 mcg and more than doubling when doses of 50 mcg or more are used.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/1101/p691.html

Oral Contraceptives Are Not an Effective Treatment for Ovarian Cysts - Cochrane for ...

Nov 1, 2014 - Oral contraceptives are not an effective treatment for ovarian cysts, whether the cysts are spontaneous or associated with medically induced ovulation. Most cysts resolve without intervention within two to three months. Those that do not resolve in this time frame are more likely to be ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/1101/p623.html

Risk of Venous Thromboembolism with Use of Combined Oral Contraceptives - Cochrane for ...

Mar 1, 2015 - All combined oral contraceptives increase VTE risk. The risk is greater for those containing desogestrel, drospirenone, gestodene (not available in the United States), and cyproterone acetate (not available in the United States) when compared with levonorgestrel. All combined oral ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0301/p287.html

Progestin-Only Contraceptives: Effects on Weight - Cochrane for Clinicians - American ...

May 1, 2014 - There is little evidence that progestin-only contraceptives cause weight gain; in this review, mean weight gain was less than 2 kg (4.4 lb) for most studies up to 12 months.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0501/p715.html

Contraceptive Education for Women After Childbirth - Cochrane for Clinicians - American...

Jun 1, 2013 - Postpartum education may increase contraceptive use and reduce unplanned repeat pregnancies, although the evidence is mixed. The optimal timing and content of educational programs are not known.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p761.html

The Effects of Combination Contraceptives on Weight - Cochrane for Clinicians - ...

Dec 1, 2012 - Compared with placebo or no intervention, the use of combination contraceptives was not associated with weight gain. Most studies comparing different types of combination contraceptives showed no statistically significant effects on weight.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1201/p1009.html

Interventions to Increase Cervical Cancer Screening Rates - Cochrane for Clinicians - ...

Mar 1, 2012 - Invitation letters are the most studied method of encouraging cervical cancer screening, and they are effective (relative risk [RR] = 1.44; 95% confidence interval [CI], 1.24 to 1.52).1–3 Invitation letters may be more cost-effective than more intensive recruitment efforts (e.g., ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0301/p443.html

Cochrane for Clinicians - Oct 1, 2005 - American Family Physician

Oct 1, 2005 - Although no difference in effectiveness has been demonstrated in existing trials, too few patients have been studied to detect small but clinically important differences in pregnancy rates. Low-dose estrogen pills have higher rates of discontinuation and bleeding disturbances.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1001/p1224a.html

Copper Intrauterine Device vs. Depot Medroxyprogesterone Acetate for Contraception - ...

Jan 1, 2011 - The copper IUD is more effective in preventing pregnancy compared with Depo-Provera.1 Each contraceptive method has different adverse effects; the evidence is too limited to make comparisons of discontinuation rates.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0101/p35.html

Same-Day Initiation of Hormonal Contraceptives - Cochrane for Clinicians - American ...

Oct 1, 2009 - Giving an injection of medroxyprogesterone (Depo-Provera) on any day of a patient's menstrual cycle decreases unintended pregnancies. For other hormonal methods, there is limited evidence. Compared with deferring until the patient's next menses, immediate start of hormonal methods ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/1001/p690.html

Contraceptive Patch and Vaginal Ring vs. Combined Oral Contraceptives - Cochrane for ...

Aug 1, 2009 - Based on moderate quality evidence, contraceptive effectiveness of the vaginal ring or patch is similar to COC. Compliance is better with the patch, but its use is discontinued more often than COCs or the ring because of adverse effects. Vaginal ring and COC users have similar rates of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0801/p232.html

Effectiveness of Insulin Sensitizing Drugs for Polycystic Ovary Syndrome - Cochrane for...

Nov 1, 2007 - Insulin sensitizing drugs are more effective than oral contraceptives alone at improving fasting insulin levels in patients with PCOS. Compared with metformin (Glucophage) alone, oral contraceptives alone better control irregular menstrual cycles and reduce androgen levels. There is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/1101/p1308.html

Advance Provision for Emergency Oral Contraception - Cochrane for Clinicians - American...

Sep 1, 2007 - Providing oral emergency contraceptives in advance to fertile women for use after unprotected sexual intercourse (i.e., advance provision) does not affect pregnancy rates, condom use, sexually transmitted infection rates, or type of contraception used. Advance provision more than ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0901/p654.html

Hormone Therapy in Postmenopausal and Perimenopausal Women - Cochrane for Clinicians - ...

Nov 1, 2006 - Relatively healthy women taking combined continuous hormone therapy have higher risks of myocardial infarction and venous thromboembolism after one year, stroke after three years, and breast cancer after five years. In women who take hormone therapy continuously for five years, there is...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/1101/p1501.html

Cyclic vs. Continuous or Extended- Cycle Combined Contraceptives - Cochrane for ...

Mar 1, 2006 - Evidence shows no difference in safety or effectiveness between cyclic and continuous or extended-cycle combined contraceptives. There are fewer menstrual symptoms with extended-cycle contraceptives. Patients’ satisfaction and adherence is similar for all types.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0301/p804.html

IVF Therapy for Unexplained Infertility - Cochrane for Clinicians - American Family ...

Jan 1, 2006 - Although IVF is used routinely for the treatment of unexplained infertility, there is limited evidence to show that it is more effective than expectant management, and there is insufficient evidence to recommend it as an alternative to other therapies such as clomiphene citrate ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0101/p63.html

Cochrane for Clinicians - Oct 1, 2005 - American Family Physician

Oct 1, 2005 - There is limited, weak evidence that a low glycemic index diet improves risk factors for CHD, but there are no randomized controlled trials (RCTs) showing a reduction in morbidity or mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1001/p1224.html

What Is the Best Collection Device for Screening Cervical Smears? - Cochrane for ...

Apr 1, 2004 - The combination of an extended-tip spatula with an endocervical brush (Cytobrush) is the most effective method for obtaining cervical cells. Detection of endocervical cells is a good indication of adequate smears and detection of disease.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0401/p1661.html

Hormonal Contraceptives and Weight Gain - Cochrane for Clinicians - American Family ...

Jan 1, 2005 - There is no causal relationship between combination contraceptives and weight gain.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/0101/p68.html

Vaginal Estrogen Preparations for Relief of Atrophic Vaginitis - Cochrane for ...

May 1, 2004 - Vaginal estrogen preparations are safe and effective as short-term treatment in patients with vaginal atrophy who are not candidates for systemic hormone therapy. Compared with estradiol products, conjugated equine estrogen creams may be associated with a higher incidence of adverse ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0501/p2111.html

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