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Breast Implant—Associated Anaplastic Large Cell Lymphoma - Editorials - American Family...

Jan 1, 2020 - In October 2019, the FDA released draft guidance offering numerous recommendations to help ensure women have access to breast implant benefit and risk information, including that manufacturers incorporate a boxed warning and patient decision checklist in the device’s labeling, and ...

American Family Physician : Editorials

https://www.aafp.org/afp/2020/0101/p8.html

Predicting the Risk of Postoperative Pulmonary Complications - Point-of-Care Guides - ...

Oct 15, 2019 - What is the best approach to evaluate postoperative pulmonary risk?

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2019/1015/p499.html

Polypharmacy: Evaluating Risks and Deprescribing - American Family Physician

Jul 1, 2019 - Polypharmacy, defined as regular use of at least five medications, is common in older adults and younger at-risk populations and increases the risk of adverse medical outcomes. There are several risk factors that can lead to polypharmacy. Patient-related factors include having multiple ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0701/p32.html

Clinically Relevant Drug-Drug Interactions in Primary Care - American Family Physician

May 1, 2019 - Drug interactions are common in the primary care setting and are usually predictable. Identifying the most important and clinically relevant drug interactions in primary care is essential to patient safety. Strategies for reducing the risk of drug-drug interactions include minimizing ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0501/p558.html

Fitness-Related Cardiac Arrhythmias - Editorials - American Family Physician

Jan 15, 2019 - How many clinicians are aware that high levels of physical fitness predispose patients to cardiac rhythm abnormalities? Find out more.

American Family Physician : Editorials

https://www.aafp.org/afp/2019/0115/p78.html

Lower Systolic BP During Antihypertensive Treatment Associated with More Deaths in ...

Jan 1, 2019 - In this small cohort study of patients older than 85 years, lower systolic blood pressure during treatment with antihypertensive medications is associated with higher death rates and greater cognitive decline.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0101/p54.html

Febuxostat Increases All-Cause and Cardiovascular Mortality Compared with Allopurinol -...

Sep 15, 2018 - For patients with gout who require treatment to lower their uric acid level, allopurinol is a safer option than febuxostat.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0915/p385.html

Bleeding with Anticoagulants: ACC Releases Expert Consensus Decision Pathway to Guide ...

Jul 1, 2018 - This Expert Consensus Decision Pathway from the American College of Cardiology (ACC) aims to provide physicians with decision-making assistance for managing bleeding events in patients taking anticoagulants.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/0701/p57.html

Broad-Spectrum Antibiotics Increase Adverse Events in Children with Acute Respiratory ...

Apr 1, 2018 - Broad-spectrum antibiotics are no more effective than narrow-spectrum antibiotics for treating acute respiratory tract infections in infants and children, and adverse events are significantly more common in children treated with broad-spectrum antibiotics.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0401/p474a.html

Assessing Bleeding Risk in Patients Taking Anticoagulants - Point-of-Care Guides - ...

Oct 1, 2017 - Family physicians are often faced with the dilemma of balancing the benefit of stroke prevention with the risk of major bleeding when deciding on anticoagulation treatment in patients with atrial fibrillation. Over the past 10 years, several decision support tools have been developed ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2017/1001/p465.html

Treating Aging with Testosterone - Editorials - American Family Physician

Oct 1, 2017 - Most patients on testosterone are being treated for normal symptoms of aging. Given that the diagnostics are questionable and the benefits are unconvincing, the risks of testosterone, some of which may be life-threatening, are not worth taking.

American Family Physician : Editorials

https://www.aafp.org/afp/2017/1001/p428.html

HIV-Associated Complications: A Systems-Based Approach - American Family Physician

Aug 1, 2017 - Persons with human immunodeficiency virus (HIV) infection often develop complications related directly to the infection, as well as to treatment. Aging, lifestyle factors, and comorbidities increase the risk of developing chronic conditions such as diabetes mellitus and chronic kidney ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0801/p161.html

Common Herbal Dietary Supplement—Drug Interactions - American Family Physician

Jul 15, 2017 - Nearly 25% of U.S. adults report concurrently taking a prescription medication with a dietary supplement. Some supplements, such as St. John’s wort and goldenseal, are known to cause clinically important drug interactions and should be avoided by most patients receiving any ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0715/p101.html

Vaccine Adverse Events: Separating Myth from Reality - American Family Physician

Jun 15, 2017 - Vaccines are one of the most successful medical advances in modern times. Most vaccine-preventable illnesses are unfamiliar to modern parents. Because of this, parents are increasingly questioning the necessity of immunizing their children, especially because no vaccine is completely ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0615/p786.html

Nonalcoholic Fatty Liver Disease: Identifying Patients at Risk of Inflammation or ...

Jun 15, 2017 - NAFLD is defined as hepatic steatosis on imaging or histology in the absence of other etiologies for secondary fat accumulation. It is usually identified during the evaluation of elevated transaminase levels in a patient without heavy alcohol intake, or found incidentally on imaging ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2017/0615/p796.html

Idarucizumab (Praxbind) for Dabigatran (Pradaxa) Anticoagulant Reversal - STEPS - ...

Jun 15, 2017 - Idarucizumab is the only anticoagulant reversal agent for dabigatran. Because of its high cost and limited data regarding clinical benefit, therapy should be reserved for patients taking dabigatran who have life-threatening bleeding or are in need of emergency surgery.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0615/p798.html

Chocolate Consumption May Make Acne Vulgaris Worse - POEMs - American Family Physician

Jan 15, 2017 - This study found a statistically significant increase in facial acne lesions among college students 48 hours after ingesting chocolate instead of jelly beans (average compared with baseline: 4.8 new lesions vs. 0.7 fewer lesions, respectively).

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0115/p122a.html

Diabetes Mellitus: Management of Gastrointestinal Complications - American Family ...

Dec 15, 2016 - Gastrointestinal disorders are common complications of diabetes mellitus and include gastroparesis, nonalcoholic fatty liver disease, gastroesophageal reflux disease, and chronic diarrhea. Symptoms of gastroparesis include early satiety, postprandial fullness, nausea, vomiting of ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1215/p980.html

Society for Vascular Surgery Releases Guideline on Managing the Diabetic Foot - ...

Nov 15, 2016 - The Society for Vascular Surgery collaborated with the American Podiatric Medical Association and the Society for Vascular Medicine to create evidence-based guidelines to improve the care of patients with a diabetic foot.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/1115/p834.html

The Risk of MI and Ischemic Stroke with Combined Oral Contraceptives - Cochrane for ...

Nov 1, 2016 - The overall risk of MI and ischemic stroke is increased in women who use combined oral contraceptives. The relative risk of MI and ischemic stroke increases as estrogen dose rises, increasing by 60% with doses of 20 mcg and more than doubling when doses of 50 mcg or more are used.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/1101/p691.html

Third-Generation Oral Contraceptives Associated with Greater Risk of PE, Stroke, and MI...

Oct 15, 2016 - Although there is risk with any current oral contraceptive combination, those that contain lower doses of estrogen, and levonorgestrel instead of desogestrel or gestodene, are associated with the least risk of ischemic stroke, myocardial infarction (MI), or pulmonary embolism (PE). ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/1015/p663.html

FDA Implements New Labeling for Medications Used During Pregnancy and Lactation - ...

Jul 1, 2016 - Deciding which medications to take during pregnancy and lactation can be a complex and individualized decision that should be discussed with a physician. The new PLLR can help remove some of the uncertainty clinicians and patients face by replacing the potentially confusing letter ...

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0701/p12.html

Weighing the Risks and Benefits of Chronic Opioid Therapy - American Family Physician

Jun 15, 2016 - Evidence supports the use of opioids for treating acute pain. However, the evidence is limited for the use of chronic opioid therapy for chronic pain. Furthermore, the risks of chronic therapy are significant and may outweigh any potential benefits. When considering chronic opioid ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0615/p982.html

CDC Develops Guideline for Opioid Prescribing - Practice Guidelines - American Family ...

Jun 15, 2016 - A recently released guideline aims to establish patient-centered approaches to initiating, managing, and discontinuing opioid use. The recommendations from the Centers for Disease Control and Prevention (CDC) emphasize the serious risks and harms associated with opioids.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/0615/p1042.html

Using the CDC Guideline and Tools for Opioid Prescribing in Patients with Chronic Pain ...

Jun 15, 2016 - The new CDC guideline is intended to help clinicians decide whether and how to prescribe opioids for chronic pain; offer safer, more effective care for patients with chronic pain; improve clinician-patient communication; and prevent opioid use disorder and opioid-related overdose.

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0615/p970.html

The Opioid Epidemic: AMA’s response - Editorials - American Family Physician

Jun 15, 2016 - With Lembke article and opioid PG

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0615/p975.html

Electronic Cigarettes for Smoking Cessation - FPIN's Help Desk Answers - American ...

Mar 15, 2016 - Nicotine-containing e-cigarettes may be more effective than placebo devices for smoking cessation. They may also aid in smoking reduction, but the quality of available evidence is low. Little is known about their safety.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0315/p492.html

Dietary Supplements: How Family Physicians Can Address Safety Concerns by Working with ...

Jan 15, 2016 - Your patients are likely using some type of dietary supplement, whether they tell you or not. What can a physician do to support and protect patients from harm if they choose to use readily available dietary supplements?

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0115/p97.html

Routine CT Scans for Occult Malignancy Not Useful in Patients with Unprovoked VTE - ...

Jan 1, 2016 - There is no advantage to adding CT of the abdomen and pelvis to a basic screening protocol for occult malignancy in patients with unprovoked VTE.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0101/p59a.html

Are Some Antidepressants Safer than Others Regarding Suicide Risk? - POEMs - American ...

Jul 1, 2015 - Mirtazapine (Remeron) and venlafaxine are associated with higher rates of completed suicide in primary care patients. Rates of suicide attempts and completion are similar with the use of selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0701/p52a.html

NSAID Use Associated with Increased Risk of Serious Bleeding and CV Events After MI - ...

Jul 1, 2015 - The use of concomitant NSAIDs in adults who receive antithrombotic therapy after MI increases the risk of serious bleeding complications and recurrent adverse CV events. This study found the highest risk among users of celecoxib (Celebrex) and diclofenac, and the lowest risk among users...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0701/p60.html

Amoxiclav Causes Diarrhea in 1 of 8 Persons Who Take It - POEMs - American Family ...

Jun 15, 2015 - The risk of diarrhea is significantly higher with amoxicillin/clavulanate (amoxiclav; Augmentin) than placebo, with a number needed to treat to harm (NNTH) of 8, which is not dissimilar from the number needed to treat for conditions such as otitis media. Contrary to popular belief, the ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0615/p877.html

Increased GI Bleeding After Switch from Warfarin to Dabigatran - POEMs - American ...

May 1, 2015 - The risk of bleeding increases (though remains small) when patients with atrial fibrillation are switched from warfarin to dabigatran to prevent stroke or transient ischemic attack. This study, conducted almost exclusively in male veterans, found an increase in gastrointestinal (GI) ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0501/p648.html

Exercise and Pregnancy Loss - FPIN's Clinical Inquiries - American Family Physician

Apr 1, 2015 - Regular exercise for up to seven or more hours per week (including low-intensity and high-intensity aerobics, jogging, cycling, and swimming) is not associated with increased rates of miscarriage in the first to mid-second trimesters. Patients may continue bending and lifting at work, ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0401/p437.html

CIN Treatment May Increase Miscarriages but Does Not Affect Fertility - POEMs - ...

Apr 1, 2015 - In this analysis of 15 observational studies (it would be difficult and unethical to do randomized research on this topic), excision using any method for CIN did not affect fertility, although second trimester miscarriages were more likely. A study published at the same time found the ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0401/p490.html

Risk of Venous Thromboembolism with Use of Combined Oral Contraceptives - Cochrane for ...

Mar 1, 2015 - All combined oral contraceptives increase VTE risk. The risk is greater for those containing desogestrel, drospirenone, gestodene (not available in the United States), and cyproterone acetate (not available in the United States) when compared with levonorgestrel. All combined oral ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0301/p287.html

Improving Quality by Doing Less: Overtreatment - Editorials - American Family Physician

Mar 1, 2015 - The third in a series of AFP editorials that addresses the related issues of over-screening, overdiagnosis, and overtreatment. Overtreatment is an important harm that commonly follows overscreening and overdiagnosis.

American Family Physician : Editorials

https://www.aafp.org/afp/2015/0301/p289.html

Cesarean Delivery: Counseling Issues and Complication Management - American Family ...

Feb 1, 2015 - Nearly one-third of all deliveries in the United States are cesarean deliveries. Compared with spontaneous vaginal delivery, cesarean delivery is associated with increased maternal and neonatal morbidity and mortality. Interventions that decrease the chance of a cesarean delivery ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0201/p178.html

The Health Consequences of Adverse Childhood Experiences: Role of the Family Physician ...

Dec 15, 2014 - Addressing adverse childhood experiences has been called the ultimate health promotion and preventive medicine intervention. Family physicians have an opportunity to prevent and intervene in children's exposure to these experiences by focusing on safe, stable, and nurturing ...

American Family Physician : Editorials

https://www.aafp.org/afp/2014/1215/p822.html

One in Five Patients Overdiagnosed with Lung Cancer Screening - POEMs - American Family...

Jul 15, 2014 - In patients screened for lung cancer using low-dose computed tomography (LDCT), more than 18% of all lung cancers found are slow-growing and will not cause symptoms or harm during an average 6.4 years of follow-up. This risk of overdiagnosis should be part of the discussion regarding ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0715/p112.html

Hip Fracture: Diagnosis, Treatment, and Secondary Prevention - American Family Physician

Jun 15, 2014 - Hip fractures cause significant morbidity and are associated with increased mortality. Women experience 80% of hip fractures, and the average age of persons who have a hip fracture is 80 years. Most hip fractures are associated with a fall, although other risk factors include decreased ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0615/p945.html

Testosterone Therapy in Men Associated with an Increase in the Risk of Nonfatal MI - ...

Jun 1, 2014 - Filling a prescription for testosterone therapy is associated with an increased likelihood of experiencing an MI, especially in older men and those with a history of cardiovascular disease.

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0601/p907.html

Complications of Adjustable Gastric Banding Surgery for Obesity - American Family ...

May 15, 2014 - Laparoscopic adjustable gastric banding procedures have a favorable risk-benefit profile and are increasingly important as part of the overall management of obesity. These procedures are effective at inducing weight loss and improving comorbid conditions, including diabetes mellitus, ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0515/p813.html

Suppurative Complications of Sore Throat Uncommon and Unpredictable - POEMs - American ...

May 15, 2014 - First, the good news. Complications of acute sore throat—peritonsillar abscess, otitis media, sinusitis, and skin infections—occur in only approximately 1% of adults. However, there is no good predictor of which adults will develop these complications. Decision tools that try to predict...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0515/p824a.html

Progestin-Only Contraceptives: Effects on Weight - Cochrane for Clinicians - American ...

May 1, 2014 - There is little evidence that progestin-only contraceptives cause weight gain; in this review, mean weight gain was less than 2 kg (4.4 lb) for most studies up to 12 months.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0501/p715.html

Pioglitazone Exposure Increases Bladder Cancer Risk - POEMs - American Family Physician

Jan 15, 2014 - This review of all available data found a significantly increased risk of bladder cancer among adults with type 2 diabetes treated with pioglitazone. Pioglitazone also significantly increases the risk of heart failure, and there is minimal, if any, patient-oriented evidence of benefit ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0115/p136.html

Risks of Bisphosphonate Use - FPIN's Clinical Inquiries - American Family Physician

Nov 15, 2013 - Bisphosphonates are associated with a small risk of atypical femoral shaft fractures, which increases with duration of use. Bisphosphonates are associated with a small risk of osteonecrosis of the jaw, which is more common in patients who are older, female, or have poor dental hygiene ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/1115/p697.html

Sexual, Urinary, and Bowel Dysfunction Common After Treatment for Localized Prostate ...

Nov 1, 2013 - Patients undergoing surgery had worse urinary and sexual outcomes, whereas those undergoing external beam radiation therapy (EBRT) had worse bowel symptoms. Watchful waiting (active surveillance) was not the subject of this study, but given the problems associated with therapy, active ...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1101/p609.html

Tubal Ectopic Pregnancy - Clinical Evidence Handbook - American Family Physician

Oct 1, 2013 - What treatments improve outcomes in women with unruptured tubal ectopic pregnancy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/1001/p459.html

Potential Harms of Computed Tomography: The Role of Informed Consent - Editorials - ...

Sep 1, 2013 - The use of CT imaging has risen dramatically in the past two decades, and there is substantial evidence that it is overused. One concern is that the harms and risks of CT have been underestimated and poorly understood, and are not often discussed with patients. These harms should be ...

American Family Physician : Editorials

https://www.aafp.org/afp/2013/0901/p294.html

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