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Lubiprostone (Amitiza) for Chronic Idiopathic Constipation - STEPS - American Family ...

Oct 15, 2006 - Although bulk or osmotic laxatives are less expensive first options for treating patients with chronic idiopathic constipation, lubiprostone is an alternative for those who do not tolerate or respond to these agents, or in patients older than 65 years in whom tegaserod use is not ...

American Family Physician : STEPS

https://www.aafp.org/afp/2006/1015/p1380.html

Methylnaltrexone (Relistor) for Opioid-Induced Constipation - STEPS - American Family ...

Sep 15, 2010 - Methylnaltrexone can temporarily relieve opioid-induced constipation in patients with advanced illness who have not responded to laxative treatment. However, it must be given by injection, is expensive, and has been studied only for short-term use.

American Family Physician : STEPS

https://www.aafp.org/afp/2010/0915/p678.html

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