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Diabetic Kidney Disease: Diagnosis, Treatment, and Prevention - American Family Physician

Jun 15, 2019 - Globally, approximately 20% of the 400 million individuals with diabetes mellitus have diabetic kidney disease (DKD). DKD is associated with higher cardiovascular and all-cause morbidity and mortality, so timely diagnosis and treatment are critical. Screening for early DKD is best done ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0615/p751.html

Kidney Disease - American Family Physician

Jun 15, 2019 - This collection features AFP content on kidney disease and related issues, including acute renal failure, chronic kidney disease, dialysis, hematuria, proteinuria, and renal disease. This collection features AFP content on kidney disease and related issues, including acute renal ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=15

Kidney Stones: Treatment and Prevention - American Family Physician

Apr 15, 2019 - Kidney stones are a common disorder, with an annual incidence of eight cases per 1,000 adults. During an episode of renal colic, the first priority is to rule out conditions requiring immediate referral to an emergency department, then to alleviate pain, preferably with a nonsteroidal ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0415/p490.html

Direct Oral Anticoagulants vs. Warfarin to Prevent Stroke and Embolic Events in ...

Apr 1, 2019 - Direct oral anticoagulants are as likely as warfarin to prevent all strokes and systemic embolic events in patients with atrial fibrillation and CKD stage 3. They do not increase the risk of major bleeding events. The evidence remains insufficient to make recommendations for the use of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0401/p422.html

Renal Cell Carcinoma: Diagnosis and Management - American Family Physician

Feb 1, 2019 - Kidney cancer is one of the 10 most common cancers in the United States with 90% being attributed to renal cell carcinoma. Men, especially black men, are more likely to be affected than women. Renal masses, either cystic or solid, are best detected with contrast-enhanced, triple-phase ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0201/p179.html

Intensive Blood Pressure Control in Older Patients Can Decrease Renal Function - POEMs ...

Jan 1, 2018 - In this post-hoc analysis of the previously published SPRINT trial, lowering the systolic blood pressure of patients who are at increased risk of cardiovascular events (average age = 66 years) will decrease their risk of cardiovascular disease but increase their likelihood of developing...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0101/p54.html

Chronic Kidney Disease: Detection and Evaluation - American Family Physician

Dec 15, 2017 - Chronic kidney disease affects 47 million people in the United States and is associated with significant health care costs, morbidity, and mortality. Because this disease can silently progress to advanced stages, early detection is critical for initiating timely interventions. Multiple ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1215/p776.html

Effects of Altered Dietary Salt Intake in Patients with Chronic Kidney Disease - ...

Apr 1, 2017 - Reducing salt intake lowers blood pressure and reduces proteinuria in patients with CKD, but there is no evidence to determine whether lowering salt consumption leads to clinically significant reductions in end-stage renal disease, cardiovascular events, or all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0401/p423.html

Proteinuria in Children: Evaluation and Differential Diagnosis - American Family Physician

Feb 15, 2017 - Although proteinuria is usually benign in the form of transient or orthostatic proteinuria, persistent proteinuria may be associated with more serious renal diseases. Proteinuria may be an independent risk factor for the progression of chronic kidney disease in children. Mechanisms of ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0215/p248.html

ACE Inhibitors or ARBs to Prevent CKD in Patients with Microalbuminuria - FPIN's ...

Oct 15, 2016 - ACE inhibitors reduce the risk of progression to macroalbuminuria in normotensive patients with microalbuminuria and type 1 diabetes mellitus.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2016/1015/p652.html

Diagnosis and Management of Nephrotic Syndrome in Adults - American Family Physician

Mar 15, 2016 - Nephrotic syndrome (NS) consists of peripheral edema, heavy proteinuria, and hypoalbuminemia, often with hyperlipidemia. Patients typically present with edema and fatigue, without evidence of heart failure or severe liver disease. The diagnosis of NS is based on typical clinical ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0315/p479.html

Ultrasonography Is Best Initial Imaging for Suspected Kidney Stones - POEMs - American ...

Jan 15, 2015 - Initial point-of-care or radiology department ultrasonography is a safe and accurate approach to the patient with clinically suspected kidney stones, which helps reduce radiation exposure. Although computed tomography (CT) remains the most accurate test overall, a strategy beginning ...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0115/p132a.html

Autosomal Dominant Polycystic Kidney Disease - American Family Physician

Sep 1, 2014 - Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney disease. Enlarging cysts within the kidneys are the clinical hallmark of the disease. Renal manifestations include varying degrees of kidney injury, urinary tract infections, kidney stones,...

American Family Physician : Article

https://www.aafp.org/afp/2014/0901/p303.html

ACP Releases Guideline on Screening, Monitoring, and Treatment of Stage 1 to 3 Chronic ...

Jul 15, 2014 - Based on a systematic evidence review, this guideline from the American College of Physicians (ACP) presents recommendations on screening, monitoring, and treatment of stage 1 to 3 chronic kidney disease in adults.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2014/0715/p121.html

No Benefit to Addition of Stenting for Treatment of Atherosclerotic Renal Artery ...

Apr 1, 2014 - In patients with severe atherosclerotic renal artery stenosis and hypertension or chronic kidney disease, renal artery stenting does not provide an additional benefit when added to comprehensive medical therapy that includes blood pressure and diabetes mellitus management, and ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0401/p576.html

Screening for Chronic Kidney Disease: Recommendation Statement - U.S. Preventive ...

Feb 15, 2014 - The U.S. Preventive Services Task Force (USPSTF) concludes that the evidence is insufficient to assess the balance of benefits and harms of routine screening for chronic kidney disease (CKD) in asymptomatic adults.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2014/0215/od1.html

Screening for Chronic Kidney Disease - Putting Prevention into Practice - American ...

Feb 15, 2014 - A 55-year-old woman with no history of diabetes mellitus or hypertension asks to be screened for chronic kidney disease (CKD). Her 88-year-old mother has end-stage renal disease and is currently undergoing renal dialysis. The patient says she wants to take all necessary precautions to ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2014/0215/p293.html

Update on the Management of Chronic Kidney Disease - American Family Physician

Oct 15, 2012 - Chronic kidney disease is common and associated with significant morbidity. Given the high risk of cardiovascular morbidity and mortality in patients with chronic kidney disease, it is important to identify and treat related risk factors. However, there is growing uncertainty about the ...

American Family Physician : Article

https://www.aafp.org/afp/2012/1015/p749.html

Acute Kidney Injury: A Guide to Diagnosis and Management - American Family Physician

Oct 1, 2012 - Acute kidney injury is characterized by abrupt deterioration in kidney function, manifested by an increase in serum creatinine level with or without reduced urine output. The spectrum of injury ranges from mild to advanced, sometimes requiring renal replacement therapy. The diagnostic ...

American Family Physician : Article

https://www.aafp.org/afp/2012/1001/p631.html

The "ARB-MI Paradox": Real or a Fluke? - AFP Journal Club - American Family Physician

Jul 15, 2012 - The Journal Club authors discuss what factors make this meta-analysis, designed to determine whether the ARB-MI paradox is real or a statistical fluke, successful.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0715/p136.html

Diabetic Nephropathy--The Family Physician's Role - American Family Physician

May 1, 2012 - Nearly one-half of persons with chronic kidney disease have diabetes mellitus. Diabetes accounted for 44 percent of new cases of kidney failure in 2008. Diabetic nephropathy, also called diabetic kidney disease, is associated with significant macrovascular risk, and is the leading cause...

American Family Physician : Article

https://www.aafp.org/afp/2012/0501/p883.html

End-Stage Renal Disease: Symptom Management and Advance Care Planning - American Family...

Apr 1, 2012 - The prevalence of end-stage renal disease continues to increase, and dialysis is offered to older and more medically complex patients. Pain is problematic in up to one-half of patients receiving dialysis and may result from renal and nonrenal etiologies. Opioids can be prescribed ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0401/p705.html

Chronic Kidney Disease: Detection and Evaluation - American Family Physician

Nov 15, 2011 - Chronic kidney disease affects an estimated 27 million adults in the United States, and is associated with significantly increased risk of cardiovascular disease and stroke. Patients should be assessed annually to determine whether they are at increased risk of developing chronic kidney...

American Family Physician : Article

https://www.aafp.org/afp/2011/1115/p1138.html

Diabetic Nephropathy: Preventing Progression - Clinical Evidence Handbook - American ...

Mar 15, 2011 - What are the effects of treatments to prevent progression of nephropathy in persons with type 1 and type 2 diabetes and early and late nephropathy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2011/0315/p732.html

End-stage Renal Disease - Clinical Evidence Handbook - American Family Physician

Dec 15, 2010 - What are the effects of different doses for peritoneal dialysis? What are the effects of different doses and membrane fluxes for hemodialysis? What are the effects of interventions aimed at preventing secondary complications?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2010/1215/p1512.html

Proteinuria in Children - American Family Physician

Sep 15, 2010 - Proteinuria is common in children and may represent a benign condition or a serious underlying renal disease or systemic disorder. Proteinuria may occur secondary to glomerular or tubular dysfunction. Although a 24-hour urine protein excretion test is usually recommended, it may be ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0915/p645.html

Statins for Non-Dialysis Chronic Kidney Disease - Cochrane for Clinicians - American ...

Jan 1, 2010 - When taken over a five-year period, statins significantly reduce all-cause mortality (number needed to treat [NNT] = 56), cardiovascular mortality (NNT = 86), and nonfatal cardiovascular events (NNT = 25).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0101/p27.html

Nephrotic Syndrome in Adults: Diagnosis and Management - American Family Physician

Nov 15, 2009 - Nephrotic syndrome may be caused by primary (idiopathic) renal disease or by a variety of secondary causes. Patients present with marked edema, proteinuria, hypoalbuminemia, and often hyperlipidemia. In adults, diabetes mellitus is the most common secondary cause, and focal segmental ...

American Family Physician : Article

https://www.aafp.org/afp/2009/1115/p1129.html

Drug-Induced Nephrotoxicity - American Family Physician

Sep 15, 2008 - Drugs are a common source of acute kidney injury. Compared with 30 years ago, the average patient today is older, has more comorbidities, and is exposed to more diagnostic and therapeutic procedures with the potential to harm kidney function. Drugs shown to cause nephrotoxicity exert ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0915/p743.html

Practice Guidelines - Sep 15, 2007 - American Family Physician

Sep 15, 2007 - Patients on dialysis are particularly susceptible to methicillin-resistant Staphylococcus aureus (MRSA) infection. The Centers for Disease Control and Prevention (CDC) reports that patients on dialysis who have invasive devices or a catheter also are at increased risk.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0915/p894.html

Practice Guidelines - Sep 15, 2007 - American Family Physician

Sep 15, 2007 - Physicians should consider the increased risks associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) and cyclooxygenase-2 (COX-2) inhibitors, according to new guidelines issued by the American Heart Association (AHA).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0915/p894a.html

Practice Guidelines - Aug 15, 2007 - American Family Physician

Aug 15, 2007 - The Centers for Disease Control and Prevention (CDC) has released a report on the racial differences in patients with end-stage renal disease (ESRD).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0815/p587a.html

Practice Guidelines - Aug 15, 2007 - American Family Physician

Aug 15, 2007 - New guidelines on the use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy are available from the American College of Obstetricians and Gynecologists (ACOG).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0815/p587.html

Acute Renal Failure - Clinical Evidence Handbook - American Family Physician

Aug 1, 2007 - What are the effects of interventions to prevent acute renal failure in persons at high risk? What are the effects of treatments for critically ill persons with acute renal failure?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2007/0801/p418.html

Angiotensin Blockade in Patients with Diabetic Nephropathy - FPIN's Clinical Inquiries ...

Aug 1, 2007 - When used to delay the progression of early nephropathy in patients with type 2 diabetes mellitus, angiotensin receptor blockers (ARBs) are not superior to angiotensin-converting enzyme (ACE) inhibitors.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2007/0801/p423.html

ACE Inhibitors vs. ARBs for Patients with Diabetic Kidney Disease - Cochrane for ...

Jul 1, 2007 - Studies comparing ACE inhibitors or ARBs with placebo found no mortality benefit in patients with diabetic kidney disease. A subgroup analysis of five studies (2,034 total patients) found that, when given at full or maximally tolerated doses, ACE inhibitors reduce all-cause mortality ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0701/p68.html

Drug Dosing Adjustments in Patients with Chronic Kidney Disease - American Family ...

May 15, 2007 - Chronic kidney disease affects renal drug elimination and other pharmacokinetic processes involved in drug disposition (e.g., absorption, drug distribution, nonrenal clearance [metabolism]). Drug dosing errors are common in patients with renal impairment and can cause adverse effects ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0515/p1487.html

Indications for Renal Arteriography at the Time of Coronary Arteriography - Practice ...

Apr 15, 2007 - A science advisory published by American Heart Association (AHA) describes the indications for renal arteriography. When possible, patients with a clinical indication for investigation of renal artery stenosis should undergo noninvasive diagnostic tests before coronary arteriography.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0415/p1258.html

Practice Guidelines - Jan 15, 2007 - American Family Physician

Jan 15, 2007 - The American Heart Association (AHA) published recommendations for the detection of chronic kidney disease in patients with cardiovascular disease (CVD). Chronic kidney disease is common in patients with CVD; moreover, it also is a risk factor for developing CVD.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0115/p268.html

Practice Guidelines - Jan 15, 2007 - American Family Physician

Jan 15, 2007 - The Centers for Disease Control and Prevention (CDC) has released data on visual impairment in patients with diabetes. Patients with diabetes are more likely to be visually impaired than those who do not have the disease.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0115/p268a.html

Hemolytic Uremic Syndrome: An Emerging Health Risk - American Family Physician

Sep 15, 2006 - Hemolytic uremic syndrome is caused primarily by Shiga toxin-producing Escherichia coli O157:H7. The most common cause of acute renal failure in children, hemolytic uremic syndrome also can occur in adults. Characteristic features of the syndrome are microangiopathic anemia, thrombotic ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0915/p991.html

CDC Reports on End-stage Renal Disease in Patients with Diabetes - Practice Guidelines ...

Aug 15, 2006 - The Centers for Disease Control and Prevention (CDC) has released a report detailing the incidence of end-stage renal disease (ESRD) in patients with diabetes. Diabetes mellitus is the leading cause of ESRD in the United States, accounting for 44 percent of new cases in 2002.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0815/p677.html

Antihypertensive Agents for Prevention of Diabetic Nephropathy - Cochrane for ...

Jul 1, 2006 - Angiotensin-converting enzyme (ACE) inhibitors are the only antihypertensive agents with proven effectiveness for the primary prevention of diabetic nephropathy (defined as an albumin excretion of less than 30 mg per day on three serial measurements) caused by type 1 or type 2 diabetes....

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0701/p77.html

Hyperkalemia - American Family Physician

Jan 15, 2006 - Hyperkalemia is a potentially life-threatening metabolic problem caused by inability of the kidneys to excrete potassium, impairment of the mechanisms that move potassium from the circulation into the cells, or a combination of these factors. Acute episodes of hyperkalemia commonly are ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0115/p283.html

Diabetic Nephropathy - Clinical Evidence Handbook - American Family Physician

Dec 1, 2005 - What are the effects of treatments in persons with type 1 diabetes and early or late nephropathy? What are the effects of treatments in persons with type 2 diabetes and early or late nephropathy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2005/1201/p2299.html

Management of Acute Renal Failure - American Family Physician

Nov 1, 2005 - Acute renal failure is present in 1 to 5 percent of patients at hospital admission and affects up to 20 percent of patients in intensive care units. The condition has prerenal, intrarenal, and postrenal causes, with prerenal conditions accounting for 60 to 70 percent of cases. The cause...

American Family Physician : Article

https://www.aafp.org/afp/2005/1101/p1739.html

Detection and Evaluation of Chronic Kidney Disease - American Family Physician

Nov 1, 2005 - Chronic kidney disease affects approximately 19 million adult Americans, and its incidence is increasing rapidly. Diabetes and hypertension are the underlying causes in most cases of chronic kidney disease. Evidence suggests that progression to kidney failure can be delayed or prevented...

American Family Physician : Article

https://www.aafp.org/afp/2005/1101/p1723.html

Evaluation of Poststreptococcal Illness - American Family Physician

May 15, 2005 - Group A beta-hemolytic streptococcal pharyngitis, scarlet fever, and rarely asymptomatic carrier states are associated with a number of poststreptococcal suppurative and nonsuppurative complications. As in streptococcal pharyngitis, acute rheumatic fever, pediatric autoimmune ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0515/p1949.html

Urinalysis: A Comprehensive Review - American Family Physician

Mar 15, 2005 - A complete urinalysis includes physical, chemical, and microscopic examinations. Midstream clean collection is acceptable in most situations, but the specimen should be examined within two hours of collection. Cloudy urine often is a result of precipitated phosphate crystals in alkaline...

American Family Physician : Article

https://www.aafp.org/afp/2005/0315/p1153.html

Chronic Kidney Disease: Prevention and Treatment of Common Complications - American ...

Nov 15, 2004 - Chronic kidney disease is a progressive condition that results in significant morbidity and mortality. Because of the important role the kidneys play in maintaining homeostasis, chronic kidney disease can affect almost every body system. Early recognition and intervention are essential ...

American Family Physician : Article

https://www.aafp.org/afp/2004/1115/p1921.html

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