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Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Treatment of Threatened Miscarriage with Progestogens - Cochrane for Clinicians - ...

Sep 1, 2019 - Progestogens reduce the risk of miscarriage when compared with placebo in patients with threatened miscarriage (number needed to treat [NNT] = 10.) Use of progestogens poses no significant risks to mother or baby.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p279.html

Misoprostol Alone is Associated with High Rate of Successful First-Trimester Abortion -...

Jul 15, 2019 - Misoprostol alone was associated with a nearly 80% success rate in the first trimester of pregnancy on meta-analysis.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0715/p119.html

Risks of Elective Labor Induction vs. Expectant Management - FPIN's Help Desk Answers -...

May 1, 2019 - Elective labor induction at 39 weeks’ gestation leads to a mean 145-g (5.1-oz) lower birth weight compared with expectant management, but there is conflicting evidence about the effects on rates of cesarean delivery, perinatal mortality, operative vaginal birth, and admission to the ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2019/0501/p587.html

Metformin for Improving Maternal and Infant Outcomes in Pregnant Women Who Are Obese - ...

Mar 1, 2019 - This meta-analysis showed no clear benefit for metformin in reducing the risk of large for gestational age infants. Additionally, there was no difference in important secondary outcomes such as gestational diabetes, hypertensive disease in pregnancy, shoulder dystocia, advanced perineal...

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2019/0301/od1.html

Complementary and Integrative Treatments for Pain Management in Labor - Cochrane for ...

Feb 1, 2019 - There is evidence that all of the studied interventions have some benefit in labor, but the evidence is of low to very low quality. Massage, thermal interventions (warm and cold packs), relaxation techniques, yoga, and music reduce pain during latent labor, but not during active labor.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0201/p154.html

Mifepristone Pretreatment Improves Success Rate of Misoprostol for Early Pregnancy Loss...

Dec 1, 2018 - In women with early pregnancy loss between five and 12 weeks' gestation, pretreatment with 200 mcg of oral mifepristone before 800 mcg of vaginal misoprostol increases the likelihood of successful expulsion of the gestational sac.

American Family Physician : POEMs

https://www.aafp.org/afp/2018/1201/p683a.html

The Pregnant Patient: Managing Common Acute Medical Problems - American Family Physician

Nov 1, 2018 - Women often see their primary care physicians for common acute conditions during pregnancy. These conditions may be caused by pregnancy (obstetric problems) or worsened by pregnancy (obstetrically aggravated problems), or they may require special consideration during pregnancy because ...

American Family Physician : Article

https://www.aafp.org/afp/2018/1101/p595.html

Epidural Analgesia and Risk of Cesarean Delivery - FPIN's Help Desk Answers - American ...

Nov 1, 2018 - There is no difference in the risk of cesarean delivery in women who receive epidural analgesia before 4 to 5 cm cervical dilation compared with later dilation.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/1101/od2.html

Effectiveness of Intrapartum Antibiotics for Meconium-Stained Amniotic Fluid - Medicine...

Nov 1, 2018 - This review concluded that there is insufficient evidence to recommend prophylactic intrapartum antibiotics in laboring women with meconium-stained amniotic fluid because of the lack of difference in rates of neonatal sepsis between the antibiotic and placebo groups.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2018/1101/od1.html

Chewing Gum for Reducing Post-Cesarean Section Ileus - Medicine by the Numbers - ...

Sep 1, 2018 - Although the current body of literature suggests a need for higher-quality, more robust research, the simplicity, frugality, and safety of chewing gum makes it a viable option to offer women undergoing cesarean section.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2018/0901/od2.html

NSAIDs for Postpartum Perineal Pain - FPIN's Help Desk Answers - American Family Physician

Jun 1, 2018 - Women with third- or fourth-degree perineal lacerations or who received an episiotomy can be given oral NSAIDs to reduce perineal pain in the first six hours postpartum.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0601/od3.html

Maternal Obesity and Labor Induction - FPIN's Help Desk Answers - American Family ...

May 15, 2018 - Pregnant women who are obese have nearly double the rate of cesarean delivery, and obesity increases the median duration of active labor by up to four hours when labor is induced. The difference in cesarean delivery rate is larger in obese primigravida patients presenting with cervical ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2018/0515/p671.html

Tranexamic Acid Decreased Death from Bleeding but Not All-Cause Mortality in Women with...

Oct 15, 2017 - In this really large study, tranexamic acid did not decrease the frequency of the primary outcome of death or hysterectomy in women with postpartum hemorrhage. However, there was a very small reduction in the rate of death from bleeding in the women treated with tranexamic acid.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/1015/od1.html

No Increased Risk of ASD, ADHD, or SGA with First-Trimester Antidepressant Use - POEMs ...

Aug 15, 2017 - This study found that maternal antidepressant use during the first trimester of pregnancy is associated with an increased risk of preterm birth, but not SGA, ASD, or ADHD. Another study in the same issue also reported no increased risk of ASD with in utero exposure to selective ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0815/p261.html

Oral NSAIDs for Perineal Pain in the Early Postpartum Period - Medicine by the Numbers ...

May 1, 2017 - Oral nonsteroidal anti-inflammatory drugs were able to adequately relieve perineal pain for many postpartum women at four hours and longer.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0501/od1.html

Vitamin E in Pregnancy - Medicine by the Numbers - American Family Physician

Apr 1, 2017 - Vitamin E supplementation in pregnant women does not show any benefit among the most patient-important outcomes.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0401/od1.html

Membrane Sweeping to Decrease Rates of Postdate Induction - FPIN's Help Desk Answers - ...

Jan 1, 2017 - In uncomplicated pregnancies, membrane sweeping at 38 to 40 weeks' gestation safely decreases the rate of postdate inductions. Membrane sweeping increases the incidence of spontaneous labor, especially in the subsequent seven days, and results in fewer pregnancies extending beyond 41 ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2017/0101/p35.html

FDA Implements New Labeling for Medications Used During Pregnancy and Lactation - ...

Jul 1, 2016 - Deciding which medications to take during pregnancy and lactation can be a complex and individualized decision that should be discussed with a physician. The new PLLR can help remove some of the uncertainty clinicians and patients face by replacing the potentially confusing letter ...

American Family Physician : Editorials

https://www.aafp.org/afp/2016/0701/p12.html

Labor Induction at Term - FPIN's Help Desk Answers - American Family Physician

Feb 15, 2016 - Oral misoprostol (Cytotec), vaginal and intracervical prostaglandins, and mechanical methods are effective for induction of labor at term. The use of intravenous oxytocin (Pitocin) increases the risk of failure to achieve vaginal delivery at 24 hours and the risk of cesarean delivery ...

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2016/0215/p266.html

Calcium Supplementation for Preventing Hypertensive Disorders in Pregnancy - Cochrane ...

Oct 1, 2015 - High-dose calcium supplementation (i.e., at least 1,000 mg per day) during pregnancy reduces the risk of developing hypertension and preeclampsia. The most significant risk reduction occurs in women at risk of hypertensive disorders and those with low-calcium diets.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1001/p570.html

Reducing Obstetric Hemorrhage: Recommendations from the National Partnership for ...

Oct 1, 2015 - A consensus bundle, with recommendations for reducing and managing obstetric hemorrhage and improving overall maternal care, has been published by the National Partnership for Maternal Safety.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2015/1001/p643.html

Nausea and Vomiting in Early Pregnancy - Clinical Evidence Handbook - American Family ...

Sep 15, 2015 - What are the effects of treatment for hyperemesis gravidarum and nausea and vomiting in early pregnancy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2015/0915/p516.html

Management of Spontaneous Vaginal Delivery - American Family Physician

Aug 1, 2015 - Most of the nearly 4 million births in the United States annually are normal spontaneous vaginal deliveries. In the first stage of labor, normal birth outcomes can be improved by encouraging the patient to walk and stay in upright positions, waiting until at least 6 cm dilation to ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0801/p202.html

Micronutrient Supplementation During Pregnancy - FPIN's Clinical Inquiries - American ...

Aug 1, 2015 - A multimicronutrient supplement is an oral tablet containing the recommended daily allowance of several vitamins and minerals. The World Health Organization does not recommend multimicronutrient supplementation because of the potential for increased neonatal mortality in some situations.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0801/p222.html

Options for Women with Unintended Pregnancy - American Family Physician

Apr 15, 2015 - Unintended pregnancy refers to unwanted, unplanned, or mistimed pregnancies. One-half of all pregnancies in the United States are unintended, and family physicians are often asked to provide counseling, support, and resources for women with unintended pregnancies. Options include ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0415/p544.html

Counseling Patients with Unintended Pregnancy - Curbside Consultation - American Family...

Apr 15, 2015 - Nearly one-half of all pregnancies in the United States are unintended. Risk factors for unintended pregnancy include limited access to contraception, less than a college education, poor social support, age between 20 and 24 years, and black race. Family physicians are often the initial...

American Family Physician : Curbside Consultation

https://www.aafp.org/afp/2015/0415/p574.html

Magnesium Sulfate for Prevention of Preterm Birth - Cochrane for Clinicians - American ...

Apr 1, 2015 - Magnesium sulfate does not delay delivery when used in patients with preterm labor. Although magnesium sulfate is not associated with any serious adverse maternal outcomes, it may be associated with an increase in total fetal, neonatal, and infant mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0401/p444.html

Cesarean Delivery: Counseling Issues and Complication Management - American Family ...

Feb 1, 2015 - Nearly one-third of all deliveries in the United States are cesarean deliveries. Compared with spontaneous vaginal delivery, cesarean delivery is associated with increased maternal and neonatal morbidity and mortality. Interventions that decrease the chance of a cesarean delivery ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0201/p178.html

Over-the-Counter Medications in Pregnancy - American Family Physician

Oct 15, 2014 - Many pregnant women take over-the-counter (OTC) medications despite the absence of randomized controlled trials to guide their use during pregnancy. Most data come from case-control and cohort studies. In 1979, the U.S. Food and Drug Administration began reviewing all prescription and ...

American Family Physician : Article

https://www.aafp.org/afp/2014/1015/p548.html

Prostaglandins to Induce Labor in Women with Asthma - FPIN's Clinical Inquiries - ...

Sep 15, 2014 - There is little evidence evaluating whether prostaglandins used to induce labor increase the risk of bronchospasm in patients with asthma. The use of dinoprostone to induce labor is not associated with asthma exacerbations or reduced oxygen saturation in patients with active asthma or a...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0915/p415.html

Common Questions About Late-Term and Postterm Pregnancy - American Family Physician

Aug 1, 2014 - Pregnancy is considered late term from 41 weeks, 0 days’ to 41 weeks, 6 days’ gestation, and postterm at 42 weeks’ gestation. Early dating of the pregnancy is important for accurately determining when a pregnancy is late- or postterm, and first-trimester ultrasonography should be ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0801/p160.html

Nausea and Vomiting of Pregnancy - American Family Physician

Jun 15, 2014 - Nausea and vomiting of pregnancy affects nearly 75% of pregnant women. The exact cause is unknown. In most cases, it is a mild, self-limited condition that can be controlled with conservative measures and has no adverse fetal sequelae. About 1% of women develop hyperemesis gravidarum, ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0615/p965.html

Misoprostol for Incomplete First Trimester Miscarriage - Cochrane for Clinicians - ...

Apr 1, 2014 - Misoprostol, administered by various routes, is as effective as expectant management and nearly as effective as uterine aspiration. All three options have high success rates for completing miscarriage. Women treated with misoprostol had higher rates of nausea, prolonged bleeding, and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0401/p523.html

Tubal Ectopic Pregnancy - Clinical Evidence Handbook - American Family Physician

Oct 1, 2013 - What treatments improve outcomes in women with unruptured tubal ectopic pregnancy?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2013/1001/p459.html

Oxytocin Augmentation During Labor with Epidural Analgesia - Cochrane for Clinicians - ...

Jun 1, 2013 - Oxytocin augmentation does not reduce the frequency of cesarean delivery, instrumental vaginal delivery, or the combined outcome of both. Oxytocin also has no effect on low five-minute Apgar scores, postpartum hemorrhage, uterine hyperstimulation, or neonatal intensive care unit ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p760.html

Contraceptive Education for Women After Childbirth - Cochrane for Clinicians - American...

Jun 1, 2013 - Postpartum education may increase contraceptive use and reduce unplanned repeat pregnancies, although the evidence is mixed. The optimal timing and content of educational programs are not known.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0601/p761.html

Epidural Analgesia for Labor Pain - Cochrane for Clinicians - American Family Physician

Aug 1, 2012 - Compared with other types of analgesia or no analgesia, epidurals offered better pain relief, but were associated with a longer second stage of labor and increased risk of instrumental vaginal delivery, maternal fever, and oxytocin (Pitocin) administration. There were no statistically ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0801/p241.html

Managing Adverse Birth Outcomes: Helping Parents and Families Cope - American Family ...

May 1, 2012 - Unexpected adverse fetal and neonatal outcomes (e.g., stillbirth, birth trauma, congenital anomalies) present a crisis for the family and the medical care team. In cases of stillbirth, the family physician should be flexible in supporting the parents’ choices, validate the loss, and ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0501/p900.html

Labor Analgesia - American Family Physician

Mar 1, 2012 - Regional analgesia has become the most common method of pain relief used during labor in the United States. Epidural and spinal analgesia are two types of regional analgesia. With epidural analgesia, an indwelling catheter is directed into the epidural space, and the patient receives a ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0301/p447.html

Treatment of HSV Infection in Late Pregnancy - FPIN's Clinical Inquiries - American ...

Feb 15, 2012 - Pregnant women with a primary or recurrent episode of genital HSV infection who are later than 36 weeks of gestation should be treated with acyclovir (Zovirax) or valacyclovir (Valtrex) for viral suppression.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2012/0215/p390.html

Ginger for the Treatment of Nausea and Vomiting in Pregnancy - FPIN's Clinical ...

Nov 15, 2011 - Ginger can be safely used to reduce nausea and vomiting in pregnancy.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/1115/od1.html

Office Management of Early Pregnancy Loss - American Family Physician

Jul 1, 2011 - The management of early pregnancy loss used to be based largely in the hospital setting, but it has shifted to the outpatient setting, allowing women to remain under the care of their family physician throughout the miscarriage process. Up to 15 percent of recognized pregnancies end in ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0701/p75.html

Magnesium Sulfate and Other Anticonvulsants for Women with Preeclampsia - Cochrane for ...

Jun 1, 2011 - Magnesium sulfate should be considered first-line treatment to prevent eclamptic seizures during labor.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0601/p1269.html

Antidepressant Use During Pregnancy - FPIN's Clinical Inquiries - American Family ...

May 15, 2011 - There are no studies that have shown any antidepressant to be absolutely safe for use during any stage of pregnancy. The use of selective serotonin reuptake inhibitors (SSRIs) or tricyclic antidepressants (TCAs) during pregnancy does not increase the risk of congenital malformations or ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/0515/p1211.html

Caring for Pregnant Women and Newborns with Hepatitis B or C - American Family Physician

Nov 15, 2010 - Family physicians encounter diagnostic and treatment issues when caring for pregnant women with hepatitis B or C and their newborns. When hepatitis B virus is perinatally acquired, an infant has approximately a 90 percent chance of becoming a chronic carrier and, when chronically ...

American Family Physician : Article

https://www.aafp.org/afp/2010/1115/p1225.html

Diagnosis and Management of Gestational Diabetes Mellitus - American Family Physician

Jul 1, 2009 - Gestational diabetes occurs in 5 to 9 percent of pregnancies in the United States and is growing in prevalence. It is a controversial entity, with conflicting guidelines and treatment protocols. Recent studies show that diagnosis and management of this disorder have beneficial effects ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0701/p57.html

Preeclampsia, Eclampsia, and Hypertension - Clinical Evidence Handbook - American ...

May 15, 2009 - What are the effects of preventive interventions in women at risk of preeclampsia? What are the effects of interventions in women who develop mild to moderate hypertension during pregnancy? What are the effects of interventions in women who develop severe preeclampsia or very high blood...

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2009/0515/p895.html

AHRQ Reviews Management of Gestational Diabetes - Practice Guidelines - American Family...

Nov 15, 2008 - The Agency for Healthcare Research and Quality (AHRQ) systematically reviewed the literature on the management of gestational diabetes. Gestational diabetes is one of the most common complications of pregnancy, affecting about 7 percent of pregnancies each year in the United States.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2008/1115/p1217.html

Recurrent Miscarriage - Clinical Evidence Handbook - American Family Physician

Oct 15, 2008 - What are the effects of treatments for unexplained recurrent miscarriage? What are the effects of treatments for recurrent miscarriage caused by antiphospholipid syndrome?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2008/1015/p977.html

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