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Vaccines for Preventing Influenza in Healthy Children, Healthy Adults, and Older Adults...

Aug 1, 2019 - Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absenteeism in children, parental absenteeism ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0801/p143.html

Preventing or Delaying Type 2 Diabetes Mellitus with Diet and Exercise - Cochrane for ...

Dec 1, 2018 - There is moderate-quality evidence that in patients with impaired glucose tolerance (IGT) defined by an abnormal 75-g two-hour glucose tolerance test, implementing changes in diet and adding physical activity together can prevent or delay the development of type 2 diabetes.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/1201/p643.html

Pulse Oximetry Screening for Critical Congenital Heart Defects in Newborns - Cochrane ...

Apr 1, 2019 - Pulse oximetry is an accurate screening test for critical congenital heart defects in newborns. Pulse oximetry is simple to use, widely available, and has moderate sensitivity (76.3%) and good specificity (99.9%). However, the prevalence of critical congenital heart defects is low, and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0401/p421.html

Prophylactic Vaccination Against Human Papillomavirus to Prevent Cervical Cancer and ...

Jan 1, 2019 - HPV vaccination in women 15 to 26 years of age prevents the development of cervical intraepithelial neoplasia (CIN) 2 and CIN 3 in women regardless of previous HPV exposure (number needed to treat [NNT] = 39). No serious adverse effects are associated with administration of the HPV ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0101/p15.html

Interventions for Increasing Fruit and Vegetable Consumption in Children Five Years and...

Oct 1, 2018 - Child feeding interventions are effective in the short term (i.e., less than 12 months) for increasing a child's intake of fruits and vegetables, but only by less than 5% of the recommended daily allowance. Conversely, parental nutrition education and multicomponent interventions, such ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/1001/p419.html

Interventions for Treatment of Overweight and Obese Children - Cochrane for Clinicians ...

Aug 1, 2018 - Interventions that include combinations of diet, physical activity, and behavior changes may reduce weight, body mass index (BMI), and BMI z-score (equivalent to BMI-for-age percentile) in overweight and obese children six to 11 years of age.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0801/p151.html

Cerebrospinal Fluid Biomarkers for Detection of Alzheimer Disease in Patients with Mild...

Jun 1, 2018 - There is insufficient evidence to support the routine use of cerebrospinal fluid (CSF) biomarkers for the detection of progressive dementias in patients with mild cognitive impairment (MCI). These tests carry the risk of overdiagnosis of dementia and, therefore, overtreatment.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0601/p714.html

Individual Behavioral Counseling for Smoking Cessation - Cochrane for Clinicians - ...

Jul 1, 2018 - Individual behavioral counseling conducted by a trained therapist provides some benefit when compared with brief counseling and support; however, this benefit is less pronounced in the context of pharmacotherapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0701/p21.html

DPP-4 Inhibitors and GLP-1 Receptor Agonists for Prevention or Delay of Type 2 Diabetes...

Apr 1, 2018 - There is only limited-quality evidence that at-risk patients taking GLP-1 receptor agonists are less likely to progress to diabetes (number needed to treat [NNT] = 23). Serious adverse events were more likely in patients taking GLP-1 receptor agonists than in patients taking placebo ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0401/p437.html

Use of Niacin for Primary or Secondary Prevention of Cardiovascular or Cerebrovascular ...

Apr 1, 2018 - Prescription niacin (nicotinic acid, vitamin B3) does not reduce myocardial infarctions, strokes, or overall mortality when used for primary or secondary prevention.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2018/0401/p436.html

Interventions for Tobacco Cessation in Patients Being Treated for or Recovering from ...

Nov 1, 2017 - Pharmacotherapy alone and pharmacotherapy plus counseling are effective for tobacco cessation among patients being treated for or recovering from alcohol and substance use disorders. Counseling interventions without pharmacotherapy are not effective for tobacco cessation among patients ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/1101/p572.html

The Effect of Statins on Dementia and Cognitive Decline - Cochrane for Clinicians - ...

Feb 1, 2017 - Statins given in later life to patients at risk of vascular disease do not prevent dementia or cognitive decline compared with placebo. Adverse effects are similar between groups.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0201/p151.html

Preventing Unintended Adolescent Pregnancy - Cochrane for Clinicians - American Family ...

Apr 1, 2017 - Among adolescents, educational interventions increase reported condom use at most recent intercourse, whereas contraceptive-promoting interventions increase use of hormonal contraception.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0401/p422.html

Interventions for Preventing Falls Among Older Adults Living in the Community - ...

Feb 1, 2017 - Structured exercise programs and home safety interventions reduce both the rate and the risk of falling among community-dwelling adults 65 years and older, whereas multifactorial assessment and intervention programs reduce the rate of falls but not the risk of falling. Vitamin D ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0201/p152.html

Fluoride Varnish for Preventing Dental Caries in Children and Adolescents - Cochrane ...

May 1, 2016 - Topically applied fluoride varnishes are safe and effective in preventing dental caries in children and adolescents. There is little information about adverse effects or treatment acceptability. Family physicians should consider incorporating fluoride varnish into childhood preventive ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0501/p743.html

Impact of Antenatal Dietary Education and Supplementation on Maternal and Infant Health...

Apr 1, 2016 - Antenatal dietary education appears to decrease the rate of preterm birth and increase infant birth weight among undernourished women. Providing balanced energy and protein supplements to pregnant women decreases the risk of stillbirth, low birth weight, and having an infant that is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0401/p557.html

Influenza Vaccination for the Prevention of Cardiovascular Disease - Cochrane for ...

Mar 1, 2016 - Influenza vaccination may reduce cardiovascular mortality in patients with established cardiovascular disease. The effect of vaccination is unclear among patients in the general population without known cardiovascular disease.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0301/p357.html

Electronic Cigarettes for Smoking Cessation - Cochrane for Clinicians - American Family...

Feb 1, 2016 - Electronic cigarettes with nicotine increase smoking cessation rates compared with placebo, with effectiveness similar to that of nicotine patches. In addition, more patients using electronic cigarettes with nicotine were able to halve their use of cigarettes than those using placebo ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0201/p178.html

Interventions Aimed at Increasing Childhood Vaccination Rates - Cochrane for Clinicians...

Nov 1, 2015 - Community discussions, community meetings, and information campaigns may increase immunization uptake in areas with only moderate vaccine use. There is no clear evidence to guide face-to-face educational interventions, and the impact of face-to-face interventions is uncertain in areas ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/1101/p775.html

Zinc Supplementation in Children Six Months to 12 Years of Age - Cochrane for ...

Jan 1, 2015 - Preventive zinc supplementation for children in low- and middle-income countries appears to reduce rates of diarrhea and may slightly reduce rates of growth failure.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2015/0101/p27.html

The Impact of Personalized Risk Communication on Screening Decisions - Cochrane for ...

Feb 1, 2014 - Patients presented with personalized risk information are more likely to make informed decisions about screening than patients who are presented with generic risk information. Individualizing risk appears to improve the accuracy of patients' risk perception and decrease anxiety.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0201/p175.html

Prevention of Herpes Zoster in Older Adults - Cochrane for Clinicians - American Family...

Nov 1, 2013 - The herpes zoster (shingles) vaccine has demonstrated effectiveness in preventing shingles in older adults. Vaccination benefit was greater in persons 60 to 69 years of age than in those 70 years and older. Local injection site reactions were common.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1101/p578.html

General Health Checks for Reducing Morbidity and Mortality - Cochrane for Clinicians - ...

Oct 1, 2013 - Although general health checks increase the number of new diagnoses, they do not decrease total, cardiovascular-related, or cancer-related morbidity or mortality. The studies in this Cochrane review have limited applicability to the current recommended practice of providing selective, ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/1001/p432.html

Antiretroviral Preexposure Prophylaxis for Preventing HIV Infection in High-Risk ...

Aug 1, 2013 - For some groups of patients at greater risk of HIV infection (e.g., serodiscordant partners, men who have sex with men and engage in high-risk behaviors, persons with multiple concurrent sex partners, persons who exchange sex for money), preexposure prophylaxis decreased the risk of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0801/p172.html

Dietary Fat Modification and the Risk of Future Cardiovascular Events and Mortality - ...

May 1, 2013 - According to the authors of this Cochrane review, reducing or modifying a patient's dietary fat intake did not lower the rates of either total or cardiovascular-related mortality when compared with usual or control diets. Reducing the intake of total or saturated fats decreased the risk...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0501/p609.html

Screening for Developmental Dysplasia of the Hip in Newborns - Cochrane for Clinicians ...

Jan 1, 2013 - Although screening increases the proportion of newborns who are treated for DDH, there is insufficient evidence that targeted or universal ultrasound screening improves long-term orthopedic outcomes.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2013/0101/p10.html

Interventions to Prevent Childhood Obesity - Cochrane for Clinicians - American Family ...

Jul 1, 2012 - Overall, children up to 12 years of age benefited from school-based obesity prevention interventions; this effect was not demonstrated among adolescents 13 years and older. Although the overall effect size was small, interventions that promoted physical activity, alone or in combination...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0701/p30.html

Cochrane for Clinicians - Oct 1, 2005 - American Family Physician

Oct 1, 2005 - Although no difference in effectiveness has been demonstrated in existing trials, too few patients have been studied to detect small but clinically important differences in pregnancy rates. Low-dose estrogen pills have higher rates of discontinuation and bleeding disturbances.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1001/p1224a.html

Interventions to Increase Cervical Cancer Screening Rates - Cochrane for Clinicians - ...

Mar 1, 2012 - Invitation letters are the most studied method of encouraging cervical cancer screening, and they are effective (relative risk [RR] = 1.44; 95% confidence interval [CI], 1.24 to 1.52).1–3 Invitation letters may be more cost-effective than more intensive recruitment efforts (e.g., ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0301/p443.html

Effect of Mammography on Breast Cancer Mortality - Cochrane for Clinicians - American ...

Dec 1, 2011 - Although mammography can lead to false-positive results, emotional stress, and unnecessary biopsies, it appears to reduce deaths from breast cancer by about 15 percent.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/1201/p1225.html

Acellular Vaccines for Preventing Pertussis in Children - Cochrane for Clinicians - ...

Sep 1, 2011 - Multicomponent (i.e., three or more) acellular vaccines are as effective as whole-cell vaccines at preventing pertussis and mild pertussis disease (e.g., cold symptoms, cough without classic whoop or cough paroxysms) in children. Adverse effects are similar to those from placebo and ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0901/p504.html

Pre-employment Examinations for Preventing Occupational Injury and Disease - Cochrane ...

Jun 1, 2011 - There is limited evidence that task-focused examinations reduce sick leave and the incidence of musculoskeletal injuries; however, general pre-employment examinations have no effect on health outcomes.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0601/p1270.html

Screening for the Early Detection and Prevention of Oral Cancer - Cochrane for ...

May 1, 2011 - Screening by visual inspection of the oral cavity does not appear to reduce deaths from oral cancer in the general population, although there is some evidence that it could be effective in high-risk patients who use tobacco and alcohol.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0501/p1047.html

Screening for Prostate Cancer: Prostate-Specific Antigen Testing Is Not Effective - ...

Apr 1, 2011 - Several large randomized controlled trials show that PSA screening does not significantly reduce prostate cancer mortality, even in a U.S. study that included black men and men with a family history of prostate cancer. However, PSA screening does lead to overdiagnosis, overtreatment, ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0401/p802.html

Influenza Vaccination of Health Care Personnel Working with Older Patients - Cochrane ...

Oct 1, 2010 - Currently, there is no high-quality evidence to support the immunization of health care personnel in long-term care facilities to reduce the spread of seasonal influenza to older residents. Immunization of personnel did reduce influenza-like illness and all-cause mortality in the ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/1001/p763.html

Effectiveness of B-Complex Vitamins for Prevention of Cardiovascular Events - Cochrane ...

Apr 1, 2010 - Eight randomized clinical trials that included 24,210 patients did not show a reduction in MI, stroke, or all-cause mortality with B-complex vitamin therapy.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0401/p850.html

Interventions to Help Patients Reduce or Eliminate the Use of Smokeless Tobacco - ...

Dec 1, 2009 - Although the studies of behavior interventions were heterogeneous in this Cochrane review, behavior interventions such as mailings, oral or dental screenings, group discussions, workplace interventions, and telephone support showed the best evidence for smokeless tobacco cessation.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/1201/p1226.html

Aerobic Activity for Cognitive Function - Cochrane for Clinicians - American Family ...

Apr 1, 2009 - Physical activity improves cardiovascular fitness in persons older than 55 years. Cognitive speed and auditory and visual attention are increased in healthy older adults who exercise.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0401/p562.html

Alendronate for Fracture Prevention in Postmenopause - Cochrane for Clinicians - ...

Sep 1, 2008 - In postmenopausal women, a 10-mg daily dose of alendronate is effective for secondary (number needed to treat [NNT] = 16) and primary (NNT = 50) prevention of vertebral fractures. It is also effective for secondary prevention of nonvertebral fractures, including hip or wrist fractures ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0901/p579.html

Antioxidant Supplements Do Not Improve Mortality and May Cause Harm - Cochrane for ...

Nov 1, 2008 - In randomized controlled trials of primary and secondary prevention, vitamins A and E, and beta-carotene supplementation increased mortality. Vitamin C and selenium supplementation had no significant effect on mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/1101/p1079.html

Abstinence-Plus Programs for Prevention of HIV - Cochrane for Clinicians - American ...

Apr 1, 2008 - Abstinence-plus is sex education that includes information on abstinence, condom use, and contraception. Compared with a variety of controls—including usual care, no intervention, or other programs—there is no evidence of increased rates of pregnancy or sexually transmitted infection ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0401/p955.html

Low Glycemic Diets for Obesity Treatment - Cochrane for Clinicians - American Family ...

Jun 1, 2008 - Compared with high glycemic index diets or conventional energy-restricted weight loss diets, low glycemic index diets better reduce body mass index (BMI) and low-density lipoprotein (LDL) cholesterol. The weighted mean difference showed that patients lost an additional 1 to 2 BMI units ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2008/0601/p1534.html

Counseling Women About Mammography: Benefits vs. Harms - Cochrane for Clinicians - ...

Sep 1, 2007 - Studies of mammography show a 0.1 percent absolute reduction in breast cancer mortality with mammography. This means that if 2,000 women are offered mammography over 10 years, one woman would have her life prolonged, 10 healthy women would be treated unnecessarily for breast cancer, and...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0901/p652.html

Antiretroviral Prophylaxis for Occupational Exposure to HIV - Cochrane for Clinicians -...

Aug 1, 2007 - The literature shows that acarbose can reduce the risk of type 2 diabetes in patients with impaired glucose tolerance or impaired fasting glucose. However, it is unclear whether the drug stops or delays the development of the disease or masks the diagnosis. There is no evidence that ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0801/p375.html

Alpha-glucosidase Inhibitors May Reduce the Risk of Type 2 Diabetes - Cochrane for ...

Aug 1, 2007 - The literature shows that acarbose can reduce the risk of type 2 diabetes in patients with impaired glucose tolerance or impaired fasting glucose. However, it is unclear whether the drug stops or delays the development of the disease or masks the diagnosis. There is no evidence that ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0801/p374.html

Fecal Occult Blood Tests Reduce Colorectal Cancer Mortality - Cochrane for Clinicians -...

Jun 1, 2007 - Fecal occult blood testing reduces colorectal cancer mortality by 16 percent. Annual testing and rehydration of samples increases testing sensitivity but also increases the number of false-positive results.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0601/p1652.html

Exercise is an Effective Intervention in Overweight and Obese Patients - Cochrane for ...

May 1, 2007 - Exercise leads to a weight loss of 1 lb, 2 oz to 16 lb, 12 oz (0.5 to 7.6 kg), compared with a 3-oz (0.1-kg) weight loss to a weight gain of 1 lb, 9 oz (0.7 kg) with no treatment. Patients participating in higher-intensity exercise lose 3 lb, 5 oz (1.5 kg) more than those participating ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0501/p1333.html

Telephone Counseling Improves Smoking Cessation Rates - Cochrane for Clinicians - ...

Mar 1, 2007 - Telephone counseling can improve long-term smoking cessation rates. Multiple proactive calls are more effective than a single reactive call.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0301/p650.html

Screening for Prostate Cancer - Cochrane for Clinicians - American Family Physician

Feb 1, 2007 - There is insufficient evidence to determine whether screening for prostate cancer reduces mortality or impacts quality of life.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0201/p336.html

Vaccines for Preventing Influenza in Older Patients - Cochrane for Clinicians - ...

Feb 1, 2007 - According to data obtained primarily from poor-quality observational studies, influenza vaccination in older persons living in long-term care facilities appears to prevent approximately 45 percent of pneumonia cases, hospital admissions, and influenza-related deaths. In older persons ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0201/p337.html

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