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A Family Physicians' Guide to Monitoring Methotrexate - American Family Physician

Oct 1, 2000 - Methotrexate has a long history of use in the treatment of various immunologic diseases, including rheumatoid arthritis and psoriasis. Although the drug is usually prescribed by a subspecialist, a family physician may assume responsibility for monitoring methotrexate therapy. Major ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1001/p1607.html

Acute Monoarthritis: Diagnosis in Adults - American Family Physician

Nov 15, 2016 - Acute monoarthritis can be the initial manifestation of many joint disorders. The most common diagnoses in the primary care setting are osteoarthritis, gout, and trauma. It is important to understand the prevalence of specific etiologies and to use the appropriate diagnostic modalities....

American Family Physician : Article

https://www.aafp.org/afp/2016/1115/p810.html

Chronic Musculoskeletal Pain in Children: Part II. Rheumatic Causes - American Family ...

Jul 15, 2006 - Primary care physicians should have a working knowledge of rheumatic diseases of childhood that manifest primarily as musculoskeletal pain. Children with juvenile rheumatoid arthritis can present with painless joint inflammation and may have normal results on rheumatologic tests. ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0715/p293.html

Clinical Utility of Common Serum Rheumatologic Tests - American Family Physician

Mar 15, 2002 - Serum rheumatologic tests are generally most useful for confirming a clinically suspected diagnosis. Testing for rheumatoid factor is appropriate when rheumatoid arthritis, Sjögren's syndrome or cryoglobulinemia is suspected. Antinuclear antibody testing is highly sensitive for ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0315/p1073.html

Clinical Utility of the Erythrocyte Sedimentation Rate - American Family Physician

Oct 1, 1999 - The erythrocyte sedimentation rate (ESR) determination is a commonly performed laboratory test with a time-honored role. However, the usefulness of this test has decreased as new methods of evaluating disease have been developed. The test remains helpful in the specific diagnosis of a ...

American Family Physician : Article

https://www.aafp.org/afp/1999/1001/p1443.html

Common Questions About the Diagnosis and Management of Fibromyalgia - American Family ...

Apr 1, 2015 - Fibromyalgia has a distinct pathophysiology involving central amplification of peripheral sensory signals. Core symptoms are chronic widespread pain, fatigue, and sleep disturbance. Most patients with fibromyalgia have muscle pain and tenderness, forgetfulness or problems concentrating,...

American Family Physician : Article

https://www.aafp.org/afp/2015/0401/p472.html

Corticosteroid Injections for Common Musculoskeletal Conditions - American Family ...

Oct 15, 2015 - Family physicians considering corticosteroid injections as part of a comprehensive treatment plan for musculoskeletal diagnoses will find few high-quality studies to assist with evidence-based decision making. Most studies of corticosteroid injections for the treatment of ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1015/p694.html

Diagnosing Acute Monoarthritis in Adults: A Practical Approach for the Family Physician...

Jul 1, 2003 - Acute monoarthritis can be the initial manifestation of many joint disorders. The first step in diagnosis is to verify that the source of pain is the joint, not the surrounding soft tissues. The most common causes of monoarthritis are crystals (i.e., gout and pseudogout), trauma, and ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0701/p83.html

Diagnosis and Management of Gout - American Family Physician

Apr 1, 1999 - Gout is a disease resulting from the deposition of urate crystals caused by the overproduction or underexcretion of uric acid. The disease is often, but not always, associated with elevated serum uric acid levels. Clinical manifestations include acute and chronic arthritis, tophi, ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0401/p1799.html

Diagnosis and Management of Rheumatoid Arthritis - American Family Physician

Dec 1, 2011 - Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis. Women, smokers, and those with a family history of the disease are most often affected. Criteria for diagnosis include having at least one joint with definite swelling that is not explained by another ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1201/p1245.html

Diagnosis and Management of Rheumatoid Arthritis - American Family Physician

Sep 15, 2005 - Rheumatoid arthritis is a chronic inflammatory disease characterized by uncontrolled proliferation of synovial tissue and a wide array of multisystem comorbidities. Prevalence is estimated to be 0.8 percent worldwide, with women twice as likely to develop the disease as men. Untreated, ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0915/p1037.html

Diagnosis and Management of Sjogren Syndrome - American Family Physician

Mar 15, 2009 - Sjogren syndrome is a systemic autoimmune disease characterized by dry eyes and dry mouth. Other organ systems are affected in many patients. Sjogren syndrome is classified as primary or secondary. In primary disease, Sjogren syndrome is a solitary process, whereas secondary disease ...

American Family Physician : Article

https://www.aafp.org/afp/2009/0315/p465.html

Diagnosis and Management of Vertebral Compression Fractures - American Family Physician

Jul 1, 2016 - Vertebral compression fractures (VCFs) are the most common complication of osteoporosis, affecting more than 700,000 Americans annually. Fracture risk increases with age, with four in 10 white women older than 50 years experiencing a hip, spine, or vertebral fracture in their lifetime. ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0701/p44.html

Diagnosis of Systemic Lupus Erythematossus - American Family Physician

Dec 1, 2003 - Systemic lupus erythematosus is a multisystem inflammatory disease that is often difficult to diagnose. Before the diagnosis can be established, four of 11 clinical and laboratory criteria must be met. Antinuclear antibody titer is the primary laboratory test used to diagnose systemic ...

American Family Physician : Article

https://www.aafp.org/afp/2003/1201/p2179.html

Diagnosis, Treatment, and Prevention of Gout - American Family Physician

Dec 15, 2014 - Gout is characterized by painful joint inflammation, most commonly in the first metatarsophalangeal joint, resulting from precipitation of monosodium urate crystals in a joint space. Gout is typically diagnosed using clinical criteria from the American College of Rheumatology. Diagnosis...

American Family Physician : Article

https://www.aafp.org/afp/2014/1215/p831.html

Diagnostic Approach to Polyarticular Joint Pain - American Family Physician

Sep 15, 2003 - Identifying the cause of polyarticular joint pain can be difficult because of the extensive differential diagnosis. A thorough history and a complete physical examination are essential. Six clinical factors are helpful in narrowing the possible causes: disease chronology, inflammation, ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0915/p1151.html

Dietary Supplements for Osteoarthritis - American Family Physician

Jan 15, 2008 - A large number of dietary supplements are promoted to patients with osteoarthritis and as many as one third of those patients have used a supplement to treat their condition. Glucosamine-containing supplements are among the most commonly used products for osteoarthritis. Although the ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0115/p177.html

Differential Diagnosis of Polyarticular Arthritis - American Family Physician

Jul 1, 2015 - Polyarticular arthritis is commonly encountered in clinical settings and has multiple etiologies. The first step is to distinguish between true articular pain and nonarticular or periarticular conditions by recognizing clinical patterns through the history and physical examination. Once...

American Family Physician : Article

https://www.aafp.org/afp/2015/0701/p35.html

Evaluation of Poststreptococcal Illness - American Family Physician

May 15, 2005 - Group A beta-hemolytic streptococcal pharyngitis, scarlet fever, and rarely asymptomatic carrier states are associated with a number of poststreptococcal suppurative and nonsuppurative complications. As in streptococcal pharyngitis, acute rheumatic fever, pediatric autoimmune ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0515/p1949.html

Gout and Hyperuricemia - American Family Physician

Feb 15, 1999 - Gout is a condition characterized by the deposition of monosodium urate crystals in the joints or soft tissue. The four phases of gout include asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and chronic tophaceous gout. The peak incidence occurs in patients 30 to ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0215/p925.html

Gout: An Update - American Family Physician

Sep 15, 2007 - Arthritis caused by gout (i.e., gouty arthritis) accounts for millions of outpatient visits annually, and the prevalence is increasing. Gout is caused by monosodium urate crystal deposition in tissues leading to arthritis, soft tissue masses (i.e., tophi), nephrolithiasis, and urate ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0915/p801.html

Hip Fracture: Diagnosis, Treatment, and Secondary Prevention - American Family Physician

Jun 15, 2014 - Hip fractures cause significant morbidity and are associated with increased mortality. Women experience 80% of hip fractures, and the average age of persons who have a hip fracture is 80 years. Most hip fractures are associated with a fall, although other risk factors include decreased ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0615/p945.html

Management of Giant Cell Arteritis and Polymyalgia Rheumatica - American Family Physician

Apr 1, 2000 - Giant cell arteritis and polymyalgia rheumatica are closely related disorders that affect persons more than 50 years of age and cause substantial morbidity. Patients with giant cell arteritis typically have a localized headache, nonspecific systemic symptoms, temporal artery tenderness ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0401/p2061.html

Omega-3 Fatty Acids - American Family Physician

Jul 1, 2004 - Omega-3 fatty acids have been shown to significantly reduce the risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease. Fatty fish, such as salmon and tuna, and fish oil are rich sources of the omega-3 fatty acids ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0701/p133.html

Osteoarthritis: Current Concepts in Diagnosis and Management - American Family Physician

Mar 15, 2000 - Most patients with osteoarthritis seek medical attention because of pain. The safest initial approach is to use a simple oral analgesic such as acetaminophen (perhaps in conjunction with topical therapy). If pain relief is inadequate, oral nonsteroidal anti-inflammatory drugs or ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0315/p1795.html

Osteoarthritis: Diagnosis and Therapeutic Considerations - American Family Physician

Mar 1, 2002 - Osteoarthritis is a common rheumatologic disorder. It is estimated that 40 million Americans and 70 to 90 percent of persons older than 75 years are affected by osteoarthritis. Although symptoms of osteoarthritis occur earlier in women, the prevalence among men and women is equal. In ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0301/p841.html

Osteoarthritis: Diagnosis and Treatment - American Family Physician

Jan 1, 2012 - Osteoarthritis is a common degenerative disorder of the articular cartilage associated with hypertrophic bone changes. Risk factors include genetics, female sex, past trauma, advancing age, and obesity. The diagnosis is based on a history of joint pain worsened by movement, which can ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0101/p49.html

Osteoarthritis: Rapid Evidence Review - American Family Physician

Apr 15, 2018 - Osteoarthritis (OA) should be suspected in patients with pain in the fingers, shoulders, hips, knees, or ankles, especially if they are older than 40 years. Patients older than 50 years who have joint pain, minimal morning stiffness, and functional impairment likely have OA. Radiography...

American Family Physician : Article

https://www.aafp.org/afp/2018/0415/p523.html

Polymyalgia Rheumatica and Giant Cell Arteritis - American Family Physician

Nov 1, 2006 - Polymyalgia rheumatica and giant cell arteritis are common, closely related vasculitic conditions that almost exclusively occur in patients older than 50 years. They may be manifestations of the same underlying disease and often coexist. Patients with polymyalgia rheumatica usually ...

American Family Physician : Article

https://www.aafp.org/afp/2006/1101/p1547.html

Polymyalgia Rheumatica and Temporal Arteritis - American Family Physician

Aug 15, 2000 - Polymyalgia rheumatica and temporal arteritis are closely related inflammatory conditions that affect different cellular targets in genetically predisposed persons. Compared with temporal arteritis, polymyalgla rheumatica is much more common, affecting one in 200 persons older than 50 ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0815/p789.html

Radiographic Assessment of Osteoarthritis - American Family Physician

Jul 15, 2001 - Osteoarthritis is one of the most prevalent and disabling chronic conditions affecting older adults and a significant public health problem among adults of working age. As the bulk of the U.S. population ages, the prevalence of osteoarthritis is expected to rise. Although the incidence ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0715/p279.html

Recognition and Management of Polymyalgia Rheumatica and Giant Cell Arteritis - ...

Nov 15, 2013 - Polymyalgia rheumatica affects proximal muscles and joints, causing disability in older adults. Giant cell arteritis affects medium and large arteries and can result in blindness. These conditions overlap significantly, often occurring together. Despite the similarities, each has ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1115/p676.html

Rheumatoid Arthritis: Common Questions About Diagnosis and Management - American Family...

Apr 1, 2018 - Rheumatoid arthritis is the most commonly diagnosed systemic inflammatory arthritis, with a lifetime prevalence of up to 1% worldwide. Women, smokers, and those with a family history of the disease are most often affected. Rheumatoid arthritis should be considered if there is at least ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p455.html

Rheumatologic Tests: A Primer for Family Physicians - American Family Physician

Aug 1, 2018 - Patients with a suspected connective tissue disorder should undergo serologic testing to confirm the diagnosis and, in some cases, to monitor disease activity and predict flares. Patients with suspected systemic lupus erythematosus should be tested for antinuclear antibodies. However, ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0801/p164.html

Systemic Lupus Erythematosus: Primary Care Approach to Diagnosis and Management - ...

Aug 15, 2016 - Systemic lupus erythematosus is an autoimmune disease that affects many systems, including the skin, musculoskeletal, renal, neuropsychiatric, hematologic, cardiovascular, pulmonary, and reproductive systems. Family physicians should be familiar with the manifestations of lupus to aid ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0815/p284.html

Systemic Sclerosis/Scleroderma: A Treatable Multisystem Disease - American Family ...

Oct 15, 2008 - Systemic sclerosis (systemic scleroderma) is a chronic connective tissue disease of unknown etiology that causes widespread microvascular damage and excessive deposition of collagen in the skin and internal organs. Raynaud phenomenon and scleroderma (hardening of the skin) are hallmarks...

American Family Physician : Article

https://www.aafp.org/afp/2008/1015/p961.html

Systemic Vasculitis - American Family Physician

Mar 1, 2011 - The systemic vasculitides are characterized by inflammation of blood vessel walls. Vessels of any type, in any organ can be affected, resulting in a broad spectrum of signs and symptoms. The heterogenous nature of vasculitides presents a diagnostic challenge. The American College of ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0301/p556.html

Treating Fibromyalgia - American Family Physician

Oct 1, 2000 - Fibromyalgia is an extremely common chronic condition that can be challenging to manage. Although the etiology remains unclear, characteristic alterations in the pattern of sleep and changes in neuroendocrine transmitters such as serotonin, substance P, growth hormone and cortisol ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1001/p1575.html

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