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Denosumab (Prolia) for Treatment of Postmenopausal Osteoporosis - STEPS - American ...

Feb 15, 2012 - Prolia is an expensive method of preventing osteoporotic hip fractures, and is associated with significant adverse effects. Safer, less expensive options exist for preventing fracture in high-risk women.

American Family Physician : STEPS

https://www.aafp.org/afp/2012/0215/p334.html

Human Parathyroid Hormone for Treating Osteoporosis - FPIN's Clinical Inquiries - ...

Feb 1, 2012 - Human parathyroid hormone should be used in patients with severe osteoporosis to decrease the rate of vertebral and nonvertebral fractures.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2012/0201/od1.html

Osteoarthritis: Diagnosis and Therapeutic Considerations - American Family Physician

Mar 1, 2002 - Osteoarthritis is a common rheumatologic disorder. It is estimated that 40 million Americans and 70 to 90 percent of persons older than 75 years are affected by osteoarthritis. Although symptoms of osteoarthritis occur earlier in women, the prevalence among men and women is equal. In ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0301/p841.html

Polymyalgia Rheumatica and Temporal Arteritis - American Family Physician

Aug 15, 2000 - Polymyalgia rheumatica and temporal arteritis are closely related inflammatory conditions that affect different cellular targets in genetically predisposed persons. Compared with temporal arteritis, polymyalgla rheumatica is much more common, affecting one in 200 persons older than 50 ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0815/p789.html

Treating Fibromyalgia - American Family Physician

Oct 1, 2000 - Fibromyalgia is an extremely common chronic condition that can be challenging to manage. Although the etiology remains unclear, characteristic alterations in the pattern of sleep and changes in neuroendocrine transmitters such as serotonin, substance P, growth hormone and cortisol ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1001/p1575.html

Osteoarthritis: Current Concepts in Diagnosis and Management - American Family Physician

Mar 15, 2000 - Most patients with osteoarthritis seek medical attention because of pain. The safest initial approach is to use a simple oral analgesic such as acetaminophen (perhaps in conjunction with topical therapy). If pain relief is inadequate, oral nonsteroidal anti-inflammatory drugs or ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0315/p1795.html

Febuxostat (Uloric) for Hyperuricemia and Gout - STEPS - American Family Physician

May 15, 2010 - Febuxostat more effectively lowers serum uric acid to goal levels than does allopurinol; however, this benefit is offset by a slightly higher incidence of adverse effects and treatment discontinuation. Until superiority for patient-oriented outcomes is shown in comparative trials with ...

American Family Physician : STEPS

https://www.aafp.org/afp/2010/0515/p1287.html

Milnacipran (Savella) for Fibromyalgia - STEPS - American Family Physician

Oct 15, 2010 - Milnacipran can decrease the overall pain scores and improve symptoms of fibromyalgia. Safety in patients with severe comorbid medical and psychiatric conditions is unknown because these groups of patients were excluded from the study.

American Family Physician : STEPS

https://www.aafp.org/afp/2010/1015/p901.html

Adalimumab (Humira) for the Treatment of Rheumatoid Arthritis - STEPS - American Family...

Dec 15, 2008 - Adalimumab used alone offers little benefit over the traditional first-line agent, methotrexate. However, it increases remission rates when combined with methotrexate in early aggressive rheumatoid arthritis and when combined with traditional DMARDs in those who have not derived benefit...

American Family Physician : STEPS

https://www.aafp.org/afp/2008/1215/p1406.html

Predicting Rheumatoid Arthritis Risk in Adults with Undifferentiated Arthritis - ...

May 15, 2008 - Early use of disease-modifying antirheumatic drugs (DMARDs) markedly reduces inflammation and joint destruction associated with RA.1,2 Therefore, with early diagnosis of RA and appropriate use of DMARDs, there is a window of opportunity to change the clinical course of this disabling ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2008/0515/p1451.html

Systemic Lupus Erythematosus - Clinical Evidence Handbook - American Family Physician

Nov 1, 2007 - What are the effects of treatments on joint (arthralgia and arthritis) symptoms and other nonorgan-threatening symptoms such as serositis and fatigue in persons with systemic lupus erythematosus (SLE)? What are the effects of interventions for cutaneous involvement in persons with SLE? ...

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2007/1101/p1351.html

Ophthalmologic Examinations in Children with Juvenile Rheumatoid Arthritis - Practice ...

Jun 15, 2007 - Guidelines on the use and frequency of ophthalmologic examinations in children with juvenile rheumatoid arthritis are available from the American Academy of Pediatrics (AAP).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0615/p1886.html

AGA Reviews the Use of Corticosteroids Immunomodulators, and Infliximab in IBD - ...

Feb 1, 2007 - The American Gastroenterological Association Institute (AGA) has issued a clinical position statement on corticosteroids, immunomodulators, and infliximab (Remicade) use in managing inflammatory bowel disease (IBD).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0201/p410.html

Cochrane for Clinicians - Feb 1, 2006 - American Family Physician

Feb 1, 2006 - At high dosages, gabapentin is moderately effective for neuropathic pain, although adverse effects are experienced as often as benefit.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0201/p435.html

Cochrane for Clinicians - Feb 1, 2006 - American Family Physician

Feb 1, 2006 - Combined with methotrexate, subcutaneous adalimumab at a dosage of 40 mg every two weeks slows the progression of rheumatoid arthritis at one year. The combination is more effective than adalimumab monotherapy. Limited evidence suggests that adalimumab is also safe and effective when ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0201/p435a.html

Is Leflunomide as Safe and Effective in the Treatment of Rheumatoid Arthritis as Other ...

Sep 1, 2003 - Compared with placebo, leflunomide improves clinical outcomes and delays radiologic progression of rheumatoid arthritis. After two years of treatment, leflunomide is as safe as sulfasalazine and more effective. Leflunomide's efficacy and adverse events are similar to those of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0901/p849.html

Are Selective COX-2 Inhibitors as Effective as NSAIDs in Patients with Rheumatoid ...

Feb 1, 2004 - The efficacy of COX-2 inhibitors is similar to that of nonselective NSAIDs in reducing the symptoms of rheumatoid arthritis.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2004/0201/p595.html

Advances in the Treatment of Early Rheumatoid Arthritis - Editorials - American Family ...

Sep 15, 2005 - Advertisement << Previous article Next article >> Sep 15, 2005 Issue Editorials Advances in the Treatment of Early Rheumatoid Arthritis EDWARD M. J. VITAL, M.B.CH.B., The General Infirmary at Leeds, Leeds, United Kingdom PAUL EMERY, M.A., M.D., University of Leeds Faculty of Medicine...

American Family Physician : Editorials

https://www.aafp.org/afp/2005/0915/p1002.html

Treating Fibromyalgia: Science vs. Art - Editorials - American Family Physician

Oct 1, 2000 - Advertisement << Previous article Next article >> Oct 1, 2000 Issue Editorials Treating Fibromyalgia: Science vs. Art DANIEL J. CLAUW, M.D., Georgetown University Medical Center, Washington, D.C. Am Fam Physician. 2000 Oct 1;62(7):1492-1494. Related Article In this issue of...

American Family Physician : Editorials

https://www.aafp.org/afp/2000/1001/p1492.html

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