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Glecaprevir/Pibrentasvir (Mavyret) for the Treatment of Chronic Hepatitis C - STEPS - ...

Nov 15, 2018 - Glecaprevir/pibrentasvir is an effective treatment for any of six genotypes of HCV infection and has few adverse effects. It can be used to treat more genotypes over a shorter duration (eight weeks for patients without cirrhosis) and is substantially less expensive than other available ...

American Family Physician : STEPS

https://www.aafp.org/afp/2018/1115/p601.html

Family Physicians Can Manage Adults with Hepatitis C - Editorials - American Family ...

Oct 1, 2018 - The Centers for Disease Control and Prevention encourages family physicians to treat patients with hepatitis C. Outcomes when primary care physicians prescribe direct-acting antivirals to patients with uncomplicated hepatitis C are comparable to those of subspecialists.

American Family Physician : Editorials

https://www.aafp.org/afp/2018/1001/p413.html

Hepatitis B Virus Vaccination and Screening: Best Practices from the ACP and CDC - ...

Jul 15, 2018 - The American College of Physicians and Centers for Disease Control and Prevention highlights the consensus among these recommendations, with recent evidence, to develop a best practice advice statement for vaccination, screening, care, and treatment of patients at risk of or who ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2018/0715/p121.html

Mildly Elevated Liver Transaminase Levels: Causes and Evaluation - American Family ...

Dec 1, 2017 - Mild, asymptomatic elevations (less than five times the upper limit of normal) of alanine transaminase and aspartate transaminase levels are common in primary care. It is estimated that approximately 10% of the U.S. population has elevated transaminase levels. An approach based on the ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1201/p709.html

Nonalcoholic Fatty Liver Disease: Identifying Patients at Risk of Inflammation or ...

Jun 15, 2017 - NAFLD is defined as hepatic steatosis on imaging or histology in the absence of other etiologies for secondary fat accumulation. It is usually identified during the evaluation of elevated transaminase levels in a patient without heavy alcohol intake, or found incidentally on imaging ...

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2017/0615/p796.html

Efficacy of Direct-Acting Antivirals Compared with Older Agents for Hepatitis C - ...

Jun 1, 2017 - Although they help patients achieve sustained viralogic response, expensive direct-acting antivirals have yet to show that they can succeed in meeting top-priority treatment goals.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0601/od1.html

Sofosbuvir/Velpatasvir (Epclusa) for Hepatitis C - STEPS - American Family Physician

May 15, 2017 - Sofosbuvir/velpatasvir is an effective treatment for patients with HCV and has minimal adverse effects. It is the preferred treatment for patients with genotype 2 or 3. As with other curative treatments, it is very expensive.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0515/p664.html

Antibiotic Prophylaxis in Patients with Cirrhosis and Upper Gastrointestinal Bleeding -...

May 1, 2017 - Antibiotics should be used for prophylaxis in hospitalized patients with cirrhosis and upper gastrointestinal bleeding. Prophylaxis reduces all-cause mortality by 21%, as well as bacterial infections and rebleeding.

American Family Physician : FPIN's Help Desk Answers

https://www.aafp.org/afp/2017/0501/p582.html

Elbasvir/Grazoprevir (Zepatier) for Hepatitis C Virus Infection - STEPS - American ...

Mar 15, 2017 - Elbasvir/grazoprevir is a safe and effective treatment for HCV genotypes 1 and 4, with or without compensated cirrhosis or HIV-1 coinfection. Patients with renal impairment, including those on hemodialysis, can use the medication.

American Family Physician : STEPS

https://www.aafp.org/afp/2017/0315/p393.html

Evaluation of Jaundice in Adults - American Family Physician

Feb 1, 2017 - Jaundice in adults can be an indicator of significant underlying disease. It is caused by elevated serum bilirubin levels in the unconjugated or conjugated form. The evaluation of jaundice relies on the history and physical examination. The initial laboratory evaluation should include ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0201/p164.html

Should Family Physicians Routinely Screen Patients for Hepatitis C? Yes: Screening ...

Jan 1, 2016 - For patients to receive appropriate care for their chronic infection and receive curative treatment, they must first know they are infected, and it all begins with screening.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2016/0101/p15.html

Should Family Physicians Routinely Screen Patients for Hepatitis C? No: One-time ...

Jan 1, 2016 - Given current scientific uncertainties, limited resources, and evolving guidelines, a reasonable middle ground would be to focus HCV testing and therapy on patients who are most likely to have long-term complications from the infection.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2016/0101/p17.html

Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults - ...

Aug 15, 2015 - P.N. is a 35-year-old man whose parents were born in southeast Asia. Although he was born in the United States, P.N. does not have any vaccination records from his childhood. During an office visit, he mentions that a relative was recently diagnosed with hepatitis B virus (HBV) ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2015/0815/p301.html

Diagnosis and Management of Hepatitis C - American Family Physician

Jun 15, 2015 - Hepatitis C virus (HCV) infection, a major cause of chronic liver disease and cirrhosis, is predominantly transmitted by exposure to blood or body fluids. The infection progresses to a chronic state in 80% of patients, whereas the virus clears completely after the acute infection in 20%...

American Family Physician : Article

https://www.aafp.org/afp/2015/0615/p835.html

Screening for Hepatitis B Virus Infection in Nonpregnant Adolescents and Adults: ...

Apr 15, 2015 - The USPSTF recommends screening for hepatitis B virus (HBV) infection in persons at high risk for infection.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2015/0415/od2.html

Screening for Hepatitis C Virus Infection in Adults: Recommendation Statement - U.S. ...

Sep 15, 2014 - The U.S. Preventive Services Task Force (USPSTF) recommends screening for hepatitis C virus (HCV) infection in persons at high risk of infection. The USPSTF also recommends offering one-time screening for HCV infection to adults born between 1945 and 1965.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2014/0915/od1.html

Screening for Hepatitis C Virus Infection in Adults - Putting Prevention into Practice ...

Sep 15, 2014 - T.S. is a 59-year-old white man born in 1955. He presents as a new patient to request a refill of his cholesterol medication. He has an unremarkable medical history. When you inquire about his social history, he reports that he has been married for 30 years, drinks a moderate amount of ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2014/0915/p405.html

Nonalcoholic Fatty Liver Disease: Diagnosis and Management - American Family Physician

Jul 1, 2013 - Nonalcoholic fatty liver disease is characterized by excessive fat accumulation in the liver (hepatic steatosis). Nonalcoholic steatohepatitis is characterized by steatosis, liver cell injury, and inflammation. The mechanism of nonalcoholic fatty liver disease is unknown but involves ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0701/p35.html

CDC Issues Recommendations for Identifying HCV Infection in Persons Born in 1945 ...

Jul 1, 2013 - Identifying HCV infection through testing is important to improve health outcomes in persons born in 1945 through 1965, because of increased risk of liver cirrhosis, hepatocellular carcinoma, and extrahepatic complications. The HCV Birth Cohort Testing Work Group, including experts from...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2013/0701/p62.html

Screening for Hepatocellular Carcinoma in Patients with Hepatitis C Virus Infection - ...

Mar 15, 2013 - There is no evidence that it is beneficial to screen for hepatocellular carcinoma in symptomatic patients with HCV.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2013/0315/od2.html

Weight Loss for Patients with Nonalcoholic Fatty Liver Disease - Cochrane for ...

Sep 1, 2012 - There are insufficient high-quality studies to determine patient-oriented outcomes of weight loss for the treatment of fatty liver disease. Nonetheless, weight loss remains a reasonable goal because it may reduce liver inflammation and improve comorbidities. In two of the studies ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/0901/p415.html

ACIP Releases Recommendations for Hepatitis B Vaccine Use in Adults - Practice ...

Aug 15, 2007 - The Advisory Committee on Immunization Practices (ACIP) has released recommendations for hepatitis B vaccine use in adults. The most effective way to prevent hepatitis B virus (HBV) infection is administration of the hepatitis B vaccine.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2007/0815/p585.html

Screening for Hepatitis C in Adults - Putting Prevention into Practice - American ...

Mar 1, 2005 - Case study: DV, a 35-year-old woman, is concerned about hepatitis C virus (HCV) infection after reading about celebrities who have the infection. She has been in a monogamous relationship for 10 years, has never used illicit drugs, and has never received a blood transfusion. She has no ...

American Family Physician : Putting Prevention into Practice

https://www.aafp.org/afp/2005/0301/p955.html

Screening for Hepatitis C in Adults: Recommendation Statement - U.S. Preventive ...

Sep 15, 2004 - This statement summarizes the U.S. Preventive Services Task Force (USPSTF) recommendations on screening for hepatitis C virus (HCV) infection based on the USPSTF’s examination of evidence specific to asymptomatic persons for HCV testing and treatment.

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2004/0915/p1113.html

Jaundice in the Adult Patient - American Family Physician

Jan 15, 2004 - Jaundice in an adult patient can be caused by a wide variety of benign or life-threatening disorders. Organizing the differential diagnosis by prehepatic, intrahepatic, and posthepatic causes may help make the work-up more manageable. Prehepatic causes of jaundice include hemolysis and ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0115/p299.html

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