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Accuracy of Dermoscopy vs. Visual Inspection for Diagnosing Melanoma in Adults - ...

Feb 1, 2020 - The addition of dermoscopy to in-person visual inspection of skin lesions increases specificity and sensitivity in the detection of melanoma. In-person evaluation with dermoscopy is more accurate than image-based assessment.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0201/p145.html

Alternative Interventions for Chronic Prostatitis/Chronic Pelvic Pain Syndrome in Men -...

Jun 1, 2019 - In men with chronic pelvic pain and urinary dysfunction who have not responded to standard medical management, extracorporeal shock wave therapy reduces symptoms and increases quality of life. Acupuncture may also provide benefit to some patients.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p677.html

Antepartum Omega-3 Fatty Acid Intake and Length of Gestation - Cochrane for Clinicians ...

Jan 1, 2020 - Omega-3 fatty acids, whether taken as supplements or consumed as part of the diet, reduce the risk of preterm birth (number needed to treat = 68) and early preterm birth (number needed to treat = 55).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0101/p17.html

Anticoagulation for the Long-term Treatment of VTE in Patients with Cancer - Cochrane ...

Jun 1, 2019 - Low-molecular-weight heparin (LMWH), vitamin K antagonists, and direct oral anticoagulants, when used to prevent recurrent VTE, have a similar impact on all-cause mortality.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0601/p676.html

Antihypertensive Drug Therapy for Mild to Moderate Hypertension During Pregnancy - ...

Oct 1, 2019 - Compared with placebo, antihypertensive drug therapy for mild to moderate hypertension (defined by the authors as a blood pressure of 140 to 169 mm Hg systolic or 90 to 109 mm Hg diastolic) caused by chronic hypertension, gestational hypertension, or preeclampsia during pregnancy does ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p403.html

Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...

May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p545.html

Combined Hormonal Contraceptives for Heavy Menstrual Bleeding - Cochrane for Clinicians...

Dec 1, 2019 - Combined oral contraceptives decrease the number of women reporting menorrhagia over six months compared with placebo (absolute risk reduction = 36.7%; number needed to treat = 2.7).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1201/p677.html

Effectiveness and Safety of Factor Xa Inhibitors in Patients with Atrial Fibrillation -...

Oct 1, 2019 - Treatment of AFib with a factor Xa inhibitor results in a decrease in the combined end point of stroke and embolic events (odds ratio [OR] = 0.89; 95% CI, 0.82 to 0.97), as well as a decrease in intracranial hemorrhage (OR = 0.50; 95% CI, 0.42 to 0.59) and all-cause mortality (OR = ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1001/p405.html

General Health Checks in Adults for Reducing Disease-Related Morbidity and Mortality - ...

Dec 1, 2019 - General health check visits have no benefit on cardiovascular morbidity or on total, cardiovascular, or cancer-related mortality. There is also no evidence that they cause patient harm.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1201/p676.html

Interventions for Reducing Childhood Obesity - Cochrane for Clinicians - American ...

Apr 1, 2020 - Individual dietary interventions alone fail to change body mass index or the standardized BMI z-score across all age groups. The impact of regular physical activity or combined dietary and physical activity interventions is modest at best.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0401/p394.html

Medication Management for Chronic Heart Failure with Preserved Ejection Fraction - ...

Jul 1, 2019 - Mineralocorticoid receptor antagonists reduce hospitalizations for patients with HFpEF. Angiotensin-converting enzyme inhibitors and angiotensin receptor blockers have not been shown to change the morbidity or mortality in patients with HFpEF.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0701/p17.html

Music Therapy for Depression - Cochrane for Clinicians - American Family Physician

Mar 1, 2020 - Moderate-quality evidence shows that music therapy added to standard care is more effective in the first three months than standard care alone for depressive symptoms based on clinician-rated outcomes and patient-reported outcomes.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0301/p273.html

Noninvasive Diagnostic Tests for Helicobacter pylori Infection - Cochrane for ...

Jul 1, 2019 - When compared with serology or stool antigen tests, the urea breath test has the highest diagnostic accuracy to identify H. pylori infection in patients without a history of gastrectomy or recent use of antibiotics or proton pump inhibitors.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0701/p16.html

OnabotulinumtoxinA for Prevention of Migraine in Adults - Cochrane for Clinicians - ...

Feb 1, 2020 - OnabotulinumtoxinA reduces the number of migraine days per month by two days compared with placebo in adults with chronic migraines.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0201/p144.html

Oral H1 Antihistamines as Add-on Therapy to Topical Treatment for Eczema - Cochrane for...

Nov 1, 2019 - In children with eczema, there is no evidence to support the addition of oral H1 antihistamines to standard treatment regimens. In adults, the use of fexofenadine (Allegra), 120 mg per day, improves patient-assessed eczema symptoms compared with placebo (number needed to treat = 11; 95%...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1101/p541.html

Pelvic Floor Muscle Training vs. Control for Urinary Incontinence in Women - Cochrane ...

Apr 1, 2020 - Use of pelvic floor muscle training to treat women with all subtypes of urinary incontinence results in improvement or cure vs. no treatment (number needed to treat [NNT] = 2.5; 95% CI, 1.4 to 5.4). Treatment with pelvic floor muscle training also results in one fewer episode of leakage...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0401/p393.html

Positional Therapy for Obstructive Sleep Apnea - Cochrane for Clinicians - American ...

Jan 1, 2020 - Positional therapy for OSA reduces scores on the apnea-hypopnea index (AHI) and Epworth Sleepiness Scale compared with no treatment. Although continuous positive airway pressure (CPAP) improves AHI scores more than positional therapy, patients seem to better tolerate positional therapy ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0101/p16.html

Renin-Angiotensin System Inhibitors vs. Other Antihypertensive Drug Classes for ...

Nov 1, 2019 - RAS inhibitors, which include angiotensin receptor blockers, angiotensin-converting enzyme inhibitors, and renin inhibitors, should not be used as first-line agents.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1101/p540.html

Saline Irrigation for Allergic Rhinitis - Cochrane for Clinicians - American Family ...

May 1, 2019 - asal saline irrigation reduces the severity of allergy symptoms for up to eight weeks vs. no treatment. It is uncertain if adding nasal saline to pharmacologic treatment further improves symptoms over pharmacologic treatment alone.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p544.html

Treatment of Threatened Miscarriage with Progestogens - Cochrane for Clinicians - ...

Sep 1, 2019 - Progestogens reduce the risk of miscarriage when compared with placebo in patients with threatened miscarriage (number needed to treat [NNT] = 10.) Use of progestogens poses no significant risks to mother or baby.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p279.html

Use of Amphetamines for Attention Deficit/Hyperactivity Disorder in Adults - Cochrane ...

Sep 1, 2019 - Amphetamines provide a clinician-rated 30% or greater reduction in ADHD symptoms when compared with placebo (number needed to treat = 5).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0901/p278.html

Vaccines for Preventing Influenza in Healthy Children, Healthy Adults, and Older Adults...

Aug 1, 2019 - Influenza vaccination reduces rates of laboratory-confirmed influenza and symptomatic influenza-like illness in healthy children, healthy adults, and older adults. There is no consistent evidence that influenza vaccination reduces school absenteeism in children, parental absenteeism ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0801/p143.html

Vitamin and Mineral Supplementation for Maintaining Cognitive Functioning in ...

Mar 1, 2020 - Vitamin and mineral supplementation has little to no beneficial effect on preserving cognitive functioning or preventing dementia in cognitively healthy adults 40 years and older.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2020/0301/p272.html

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