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Detrimental Effect of Tight Glucose Control on CV Mortality Persists Over Nine Years - ...

Mar 15, 2017 - The initial Action to Control Cardiovascular Risk in Diabetes (ACCORD) study, which compared standard treatment with intensive control, found that despite good intentions, cardiovascular (CV) and overall mortality are significantly higher when blood glucose levels are lower.

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0315/od2.html

Diabetes Mellitus: Management of Gastrointestinal Complications - American Family ...

Dec 15, 2016 - Gastrointestinal disorders are common complications of diabetes mellitus and include gastroparesis, nonalcoholic fatty liver disease, gastroesophageal reflux disease, and chronic diarrhea. Symptoms of gastroparesis include early satiety, postprandial fullness, nausea, vomiting of ...

American Family Physician : Article

https://www.aafp.org/afp/2016/1215/p980.html

Society for Vascular Surgery Releases Guideline on Managing the Diabetic Foot - ...

Nov 15, 2016 - The Society for Vascular Surgery collaborated with the American Podiatric Medical Association and the Society for Vascular Medicine to create evidence-based guidelines to improve the care of patients with a diabetic foot.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2016/1115/p834.html

Newer Sulfonylureas Not Associated with Increased Mortality, MIs, or Strokes - POEMs - ...

Sep 1, 2016 - In multiple randomized trials, the long-term use of second- or third-generation sulfonylureas in patients with type 2 diabetes is not associated with more deaths, myocardial infarctions (MIs), or strokes. The included trials tended not to report other safety data.

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0901/p386.html

Pioglitazone Exposure Increases Bladder Cancer Risk - POEMs - American Family Physician

Jan 15, 2014 - This review of all available data found a significantly increased risk of bladder cancer among adults with type 2 diabetes treated with pioglitazone. Pioglitazone also significantly increases the risk of heart failure, and there is minimal, if any, patient-oriented evidence of benefit ...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0115/p136.html

Does Metformin Increase the Risk of Fatal or Nonfatal Lactic Acidosis? - Cochrane for ...

Nov 1, 2010 - In patients without standard contraindications to metformin therapy, metformin does not increase the risk of lactic acidosis.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/1101/p1068.html

Treating Diabetic Peripheral Neuropathic Pain - American Family Physician

Jul 15, 2010 - Diabetic peripheral neuropathic pain affects the functionality, mood, and sleep patterns of approximately 10 to 20 percent of patients with diabetes mellitus. Treatment goals include restoring function and improving pain control. Patients can realistically expect a 30 to 50 percent ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0715/p151.html

Diabetes: Foot Ulcers and Amputations - Clinical Evidence Handbook - American Family ...

Oct 15, 2009 - What are the effects of interventions to prevent foot ulcers and amputations in persons with diabetes? What are the effects of treatments in persons with diabetes with foot ulceration?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2009/1015/p789.html

Becaplermin (Regranex) for Diabetic Foot Ulcers - STEPS - American Family Physician

Jul 15, 2008 - Although patients treated with becaplermin are more likely to experience complete and faster ulcer healing than patients continuing good wound care alone, the increased risk of cancer mortality and significant cost outweigh the possible benefits in most patients.

American Family Physician : STEPS

https://www.aafp.org/afp/2008/0715/p255.html

Diabetic Foot Infection - American Family Physician

Jul 1, 2008 - Foot infections are common in patients with diabetes and are associated with high morbidity and risk of lower extremity amputation. Diabetic foot infections are classified as mild, moderate, or severe. Gram-positive bacteria, such as Staphylococcus aureus and beta-hemolytic ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0701/p71.html

Gastrointestinal Complications of Diabetes - American Family Physician

Jun 15, 2008 - Gastrointestinal complications of diabetes include gastroparesis, intestinal enteropathy (which can cause diarrhea, constipation, and fecal incontinence), and nonalcoholic fatty liver disease. Patients with gastroparesis may present with early satiety, nausea, vomiting, bloating, ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0615/p1697.html

CDC Reports on End-stage Renal Disease in Patients with Diabetes - Practice Guidelines ...

Aug 15, 2006 - The Centers for Disease Control and Prevention (CDC) has released a report detailing the incidence of end-stage renal disease (ESRD) in patients with diabetes. Diabetes mellitus is the leading cause of ESRD in the United States, accounting for 44 percent of new cases in 2002.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0815/p677.html

Evaluation and Prevention of Diabetic Neuropathy - American Family Physician

Jun 1, 2005 - Diabetic neuropathy is a debilitating disorder that occurs in nearly 50 percent of patients with diabetes. It is a late finding in type 1 diabetes but can be an early finding in type 2 diabetes. The primary types of diabetic neuropathy are sensorimotor and autonomic. Patients may ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0601/p2123.html

Diabetic Ketoacidosis - American Family Physician

May 1, 2005 - A diagnosis of diabetic ketoacidosis requires the patient's plasma glucose concentration to be above 250 mg per dL (although it usually is much higher), the pH level to be less than 7.30, and the bicarbonate level to be 18 mEq per L or less. Beta-hydroxybutyrate is a better measurement ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0501/p1705.html

Hyperosmolar Hyperglycemic State - American Family Physician

May 1, 2005 - Hyperosmolar hyperglycemic state is a life-threatening emergency manifested by marked elevation of blood glucose, hyperosmolarity, and little or no ketosis. With the dramatic increase in the prevalence of type 2 diabetes and the aging population, this condition may be encountered more ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0501/p1723.html

Hyperglycemic Crises: Improving Prevention and Management - Editorials - American ...

May 1, 2005 - Advertisement << Previous article Next article >> May 1, 2005 Issue Editorials Hyperglycemic Crises: Improving Prevention and Management ABBAS E. KITABCHI, PH.D., M.D.,University of Tennessee Health Science Center,Memphis,Tennessee Am Fam Physician. 2005 May 1;71(9):1659-1660. See...

American Family Physician : Editorials

https://www.aafp.org/afp/2005/0501/p1659.html

IDSA Releases Guidelines on the Diagnosis and Treatment of Diabetic Foot Infections - ...

Apr 1, 2005 - Guidelines for the diagnosis and treatment of diabetic foot infections have been developed by the Infectious Diseases Society of America (IDSA). In persons with diabetes, foot infections can cause substantial morbidity and are the most common nontraumatic cause of amputations.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2005/0401/p1429.html

Cochrane for Clinicians - Dec 1, 2004 - American Family Physician

Dec 1, 2004 - Combined evidence from two clinical trials of calcium supplementation lasting for several years revealed a reduced rate of recurrent colorectal adenoma. However, evidence is insufficient to recommend supplementation with dietary calcium for patients who have never had an adenoma.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/1201/p2109.html

Diabetic Foot Ulcers: Pathogenesis and Management - American Family Physician

Nov 1, 2002 - Foot ulcers are a significant complication of diabetes mellitus and often precede lower-extremity amputation. The most frequent underlying etiologies are neuropathy, trauma, deformity, high plantar pressures, and peripheral arterial disease. Thorough and systematic evaluation and ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1101/p1655.html

Charcot Foot: The Diagnostic Dilemma - American Family Physician

Nov 1, 2001 - Primary care physicians involved in the management of patients with diabetes are likely to encounter the diagnostic and treatment challenges of pedal neuropathic joint disease, also known as Charcot foot. The acute Charcot foot is characterized by erythema, edema and elevated ...

American Family Physician : Article

https://www.aafp.org/afp/2001/1101/p1591.html

Management of the Hyperosmolar Hyperglycemic Syndrome - American Family Physician

Oct 1, 1999 - Hyperglycemic hyperosmolarity is part of a clinical spectrum of severe hyperglycemic disorders ranging from pure hyperglycemic hyperosmolarity without ketosis to diabetic ketoacidosis, with significant overlap in the middle. From 50 to 75 percent of hospitalizable patients who have ...

American Family Physician : Article

https://www.aafp.org/afp/1999/1001/p1468.html

Management of Diabetic Ketoacidosis - American Family Physician

Aug 1, 1999 - Diabetic ketoacidosis is an emergency medical condition that can be life-threatening if not treated properly. The incidence of this condition may be increasing, and a 1 to 2 percent mortality rate has stubbornly persisted since the 1970s. Diabetic ketoacidosis occurs most often in ...

American Family Physician : Article

https://www.aafp.org/afp/1999/0801/p455.html

Diabetic Foot Ulcers: Prevention, Diagnosis and Classification - American Family Physician

Mar 15, 1998 - Diabetic ulcers are the most common foot injuries leading to lower extremity amputation. Family physicians have a pivotal role in the prevention or early diagnosis of diabetic foot complications. Management of the diabetic foot requires a thorough knowledge of the major risk factors for...

American Family Physician : Article

https://www.aafp.org/afp/1998/0315/p1325.html

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