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Benzodiazepines and Alzheimer Disease - AFP Journal Club - American Family Physician

Feb 1, 2015 - Benzodiazepine exposure over the preceding five years seems to be associated with an increased likelihood of an Alzheimer disease diagnosis. A dose-response gradient also seems to exist.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2015/0201/p191.html

Is Intensive Blood Pressure Control Beneficial in Patients with Acute Intracerebral ...

Jan 15, 2014 - It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2014/0115/p120.html

Transient Ischemic Attack: The Rules Have Changed - AFP Journal Club - American Family ...

Jun 15, 2012 - This scientific guideline includes three game changers for physicians regarding TIA. The Journal Club authors discuss why physicians should be wary of clinical guidelines that are based on expert opinion.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0615/p1179.html

Rivaroxaban vs. Warfarin for Stroke Prevention in Patients with Nonvalvular Atrial ...

Mar 15, 2012 - How does rivaroxaban compare with warfarin for stroke prevention in patients with nonvalvular atrial fibrillation? This study concluded that rivaroxaban is noninferior to warfarin. However, noninferiority trials do not meet the same rigorous design and statistical format of traditional ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0315/p577.html

Donepezil to Manage Alzheimer Disease: New vs. Standard Dosing - AFP Journal Club - ...

Mar 15, 2011 - Does donepezil benefit patients with Alzheimer disease, and is the new dosage superior to the standard dosage? This study showed benefit, but the data are misleading.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2011/0315/p742.html

Is Telmisartan Effective for Stroke Prevention? - AFP Journal Club - American Family ...

Nov 15, 2009 - Does telmisartan therapy after stroke prevent recurrence and adverse cardiovascular events? Despite lowering blood pressure, telmisartan did not provide preventative benefit. This study reflects problems with publication bias and that surrogate markers, such as blood pressure control, ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/1115/p1042.html

Is the San Francisco Syncope Rule Reliable? - AFP Journal Club - American Family Physician

Sep 15, 2009 - Can the San Francisco Syncope Rule successfully determine which patients can be safely discharged after an acute syncopal episode? External validation suggests that the sensitivity of the rule is lower than first reported. Physicians need to apply their clinical acumen and override the ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/0915/p558.html

Acyclovir or Steroids as Pharmacologic Treatment of Bell Palsy - AFP Journal Club - ...

Mar 15, 2009 - Does acyclovir or steroids speed recovery in adults with Bell palsy? This study suggests that it is reasonable to start prednisolone in some cases, but physicians should not forget about practical considerations, such as lubricant eye drops, pain management, and chewing instruction. ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/0315/p435.html

Treatment of Acute Ischemic Stroke with t-PA - AFP Journal Club - American Family ...

Apr 1, 2008 - Does the widespread use of the thrombolytic tissue plasminogen activator (t-PA) more beneficial or harmful in patients with acute stroke? The benefits must be balanced against the harms. Informed consent is necessary when making the decision.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2008/0401/p901.html

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