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Dual Antiplatelet Therapy for High-Risk TIA and Minor Stroke: BMJ Rapid Recommendation ...

Sep 15, 2019 - Based on a recent randomized controlled trial followed by a systematic review, the BMJ and MAGIC group concluded that dual antiplatelet therapy use for a limited period after mild stroke is beneficial.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2019/0915/p378.html

Short-Term Clopidogrel Plus Aspirin Prevents Second Ischemic Stroke Better Than Aspirin...

Aug 15, 2019 - Combined treatment with clopidogrel and aspirin, started within 24 hours of the first event, will decrease the likelihood of a recurrent stroke in an additional 2% of patients compared with aspirin alone, with a slight increase in the risk of extra-cranial bleeding.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0815/p249.html

Clopidogrel Plus Aspirin Provides More Net Benefit Than Aspirin Alone After Minor ...

Feb 1, 2019 - This study provides support for a strategy of adding clopidogrel to aspirin for the first week or so after a minor ischemic stroke or TIA because this is when the greatest benefit occurs. Harms were spread fairly evenly throughout the study period.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0201/p188a.html

Routine Oxygen Supplementation After Acute Stroke Does Not Improve Functional Outcomes ...

Apr 15, 2018 - For nonhypoxic patients with acute stroke, routine oxygen therapy for 72 hours, either continuously or at night only, does not improve functional outcomes at 90 days. Long-term outcomes were not assessed in this study, and the question remains whether 90 days is an adequate length of ...

American Family Physician : POEMs

https://www.aafp.org/afp/2018/0415/p533.html

Physical Fitness Training for Patients with Stroke - Cochrane for Clinicians - American...

Jun 1, 2017 - There is moderate-quality evidence that physical fitness training improves disability after stroke. Cardiovascular training that includes only aerobic exercise has a moderate effect on disability (standard mean difference [SMD] = 0.52 on a pooled disability scale), although it is not ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0601/p701.html

Pioglitazone After Stroke or TIA Reduces Stroke and MI, but Also Has Significant Harms ...

Aug 15, 2016 - In patients with a recent stroke or TIA and evidence of insulin resistance, pioglitazone reduces the likelihood of myocardial infarction (MI) or stroke (number needed to treat [NNT] = 36 over five years) but increases the risk of significant weight gain (number needed to treat to harm ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0815/p319.html

Real-World Study Finds Lower Mortality and Stroke Risk with Dabigatran, but More GI ...

Sep 15, 2015 - In this well-designed observational study, older patients given an initial prescription of dabigatran had lower all-cause mortality and fewer ischemic and hemorrhagic strokes, but a higher risk of gastrointestinal (GI) bleeding, than a matched group of patients given warfarin.

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0915/p529.html

CEA vs. Stenting: Mixed Results, Mostly Bad - POEMs - American Family Physician

Jul 1, 2015 - These two randomized trials, one with short-term outcomes and the other with five-year outcomes, demonstrate that carotid artery stenting results in more frequent strokes (clinical and radiographically detected) than carotid endarterectomy (CEA). However, the rate of fatal and disabling...

American Family Physician : POEMs

https://www.aafp.org/afp/2015/0701/p52.html

AHA and ASA Release Guideline for Prevention of Future Stroke in Patients with Stroke ...

Jan 15, 2015 - The American Heart Association (AHA) and American Stroke Association (ASA) have updated their guideline on prevention of future stroke in patients with a history of stroke or transient ischemic attack (TIA). Currently, the average annual rate of future stroke in these patients is at a ...

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2015/0115/p136.html

Is Intensive Blood Pressure Control Beneficial in Patients with Acute Intracerebral ...

Jan 15, 2014 - It seems to be safe to lower systolic blood pressure to a target of 140 mm Hg in those with an acute hemorrhagic stroke. However, there seems to be no clinical benefit to this approach when the data are adjusted for baseline NIH Stroke Scale scores.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2014/0115/p120.html

Clopidogrel Plus 21 Days of Aspirin Is Superior to Aspirin Alone Within First 24 Hours ...

Jan 1, 2014 - Patients with minor stroke (National Institutes of Health [NIH] Stroke Scale score ≤ 3) or TIA have a decreased risk of recurrent stroke if given aspirin plus clopidogrel vs. aspirin alone if started within 24 hours of the onset of symptoms. There was no significant increase in the risk...

American Family Physician : POEMs

https://www.aafp.org/afp/2014/0101/p55.html

Insulin for Glycemic Control in Acute Ischemic Stroke - Cochrane for Clinicians - ...

Dec 1, 2012 - Administering insulin to maintain glycemic control does not improve the rates of mortality or dependency, or the final neurologic outcome after an acute ischemic stroke. Additionally, in randomized controlled trials, patients in the intervention groups (those under tight glycemic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1201/p1008.html

Transient Ischemic Attack: Part II. Risk Factor Modification and Treatment - American ...

Sep 15, 2012 - Interventions following a transient ischemic attack are aimed at preventing a future episode or stroke. Hypertension, current smoking, obesity, physical inactivity, diabetes mellitus, and dyslipidemia are all well-known risk factors, and controlling these factors can have dramatic ...

American Family Physician : Article

https://www.aafp.org/afp/2012/0915/p527.html

Rivaroxaban vs. Warfarin for Stroke Prevention in Patients with Nonvalvular Atrial ...

Mar 15, 2012 - How does rivaroxaban compare with warfarin for stroke prevention in patients with nonvalvular atrial fibrillation? This study concluded that rivaroxaban is noninferior to warfarin. However, noninferiority trials do not meet the same rigorous design and statistical format of traditional ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2012/0315/p577.html

Subacute Management of Ischemic Stroke - American Family Physician

Dec 15, 2011 - Ischemic stroke is the third leading cause of death in the United States and a common reason for hospitalization. The subacute period after a stroke refers to the time when the decision to not employ thrombolytics is made up until two weeks after the stroke occurred. Family physicians ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1215/p1383.html

Treatment of Acute Ischemic Stroke with t-PA - AFP Journal Club - American Family ...

Apr 1, 2008 - Does the widespread use of the thrombolytic tissue plasminogen activator (t-PA) more beneficial or harmful in patients with acute stroke? The benefits must be balanced against the harms. Informed consent is necessary when making the decision.

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2008/0401/p901.html

Occupational Therapy Improves Activities of Daily Living After Stroke - Cochrane for ...

Jun 1, 2007 - Compared with standard rehabilitation, ADL-based occupational therapy significantly decreases death or institutionalization and deterioration in the ability to perform ADL after stroke. The optimal length and type of therapy is not well defined.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2007/0601/p1651.html

Warfarin for Prevention of Ischemic Stroke Recurrence? - FPIN's Clinical Inquiries - ...

Jun 1, 2006 - There is no evidence that anticoagulation with warfarin, initiated after a noncardioembolic ischemic stroke, significantly reduces stroke recurrence. Furthermore, anticoagulation significantly increases the risk of fatal and nonfatal hemorrhagic stroke and extracranial hemorrhage in ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2006/0601/p2011.html

Practice Guidelines - May 15, 2006 - American Family Physician

May 15, 2006 - The Centers for Disease Control and Prevention (CDC) is investigating an outbreak of mumps that began in Iowa in December 2005. Other cases that were thought to be linked to the Iowa outbreak were being investigated in Illinois, Kansas, Minnesota, Missouri, Nebraska, and Wisconsin.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0515/p1847.html

Practice Guidelines - May 15, 2006 - American Family Physician

May 15, 2006 - A subcommittee of the American Academy of Neurology (AAN) reviewed articles on carotid endarterectomy to assess the effectiveness of the procedure in preventing stroke in patients with internal carotid artery stenosis.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2006/0515/p1847a.html

Transient Ischemic Attacks: Part II. Treatment - American Family Physician

Apr 1, 2004 - Risk factors for stroke should be evaluated in patients who have had a transient ischemic attack. Blood pressure, lipid levels, and diabetes mellitus should be controlled. When applicable, smoking cessation and weight loss also are important. Angiotensin-converting enzyme inhibitor ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0401/p1681.html

Decreasing the Morbidity, Mortality, and Cost of Stroke Through Awareness and ...

Dec 15, 2003 - Advertisement << Previous article Next article >> Dec 15, 2003 Issue Editorials Decreasing the Morbidity, Mortality, and Cost of Stroke Through Awareness and Prevention MARGARET GRADISON, M.D., Duke University Medical Center, Durham, North Carolina Am Fam Physician. 2003 Dec...

American Family Physician : Editorials

https://www.aafp.org/afp/2003/1215/p2335.html

Are Anticoagulants Better than Antiplatelet Agents for Treatment of Acute Ischemic ...

Oct 1, 2003 - Aspirin has a small benefit for long-term outcome and survival. Anticoagulants increase the risk for bleeding and do not have long-term benefit.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/1001/p1307.html

Does Long-Term Anticoagulation Improve Function After Stroke? - Cochrane for Clinicians...

Jun 1, 2003 - There is no evidence that anticoagulation with either heparin or warfarin improves these outcomes. There is clear evidence of increased hemorrhagic complications (both fatal and nonfatal) in patients who receive anticoagulation.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2003/0601/p2317.html

When to Operate in Carotid Artery Disease - American Family Physician

Jan 15, 2000 - Carotid endarterectomy has proved to be beneficial in the prevention of stroke in selected patients. The procedure is indicated in symptomatic patients with carotid-territory transient ischemic attacks or minor strokes who have carotid artery stenosis of 70 to 99 percent. With a low ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0115/p400.html

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