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Intravenous Magnesium Sulfate for Acute Asthma Exacerbations - FPIN's Clinical ...

Jan 15, 2019 - Patients presenting to the emergency department with an acute asthma exacerbation that has not responded to first-line therapy (bronchodilators and corticosteroids) can be treated effectively with intravenous magnesium sulfate.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0115/p127.html

Dual Antiplatelet Therapy for Patients with Cardiovascular Disease - FPIN's Clinical ...

Oct 15, 2019 - Patients with established cardiovascular disease or risk factors (e.g., ischemic cerebrovascular disease, peripheral arterial disease, high risk of atherothrombotic disease) should receive dual antiplatelet therapy with aspirin plus clopidogrel, which confers additional benefit over ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/1015/p463.html

Gabapentin for Treatment of Radicular Low Back Pain - FPIN's Clinical Inquiries - ...

Sep 1, 2019 - Gabapentin is not effective for the treatment of radicular low back pain and is associated with adverse effects.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0901/p309.html

Angiotensin-Converting Enzyme Inhibitors vs. Angiotensin Receptor Blockers - FPIN's ...

Feb 1, 2015 - ACE inhibitors should be used in patients with hypertension because they reduce all-cause mortality, whereas ARBs do not.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0201/p193.html

Metformin for Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis - ...

Feb 15, 2019 - Metformin does not seem to be an effective treatment for nonalcoholic steatohepatitis. There are no studies evaluating whether metformin improves long-term patient-oriented outcomes such as progression from NAFLD to nonalcoholic steatohepatitis, cirrhosis, hepatocellular carcinoma, or ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0215/p262.html

Bridging Warfarin Before Colonoscopy in Patients with Atrial Fibrillation - FPIN's ...

Apr 15, 2019 - A limited number of trials that examined the risk of temporary interruption of anticoagulation before a variety of procedures did not find a reduction in the risk of stroke, but they did show an increased risk of bleeding events and venous thromboembolism (VTE) in patients who were ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0415/p519.html

H. pylori Screening Before Initiation of Long-term NSAIDs - FPIN's Clinical Inquiries -...

Jun 15, 2019 - Physicians should perform laboratory screening for and eradicate H. pylori before initiating long-term NSAID therapy in NSAID-naive patients to reduce the risk of peptic ulcer disease.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2019/0615/p783.html

ACE Inhibitors or ARBs to Prevent CKD in Patients with Microalbuminuria - FPIN's ...

Oct 15, 2016 - ACE inhibitors reduce the risk of progression to macroalbuminuria in normotensive patients with microalbuminuria and type 1 diabetes mellitus.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2016/1015/p652.html

Morning vs. Evening Administration of Levothyroxine - FPIN's Clinical Inquiries - ...

Oct 15, 2018 - The effectiveness of levothyroxine for reducing TSH levels is most dependent on the timing of meals in relation to drug administration. There is conflicting evidence. In two studies, levothyroxine taken at least two hours after eating in the evening maintained or improved TSH levels ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/1015/p532.html

Physical Therapy for Low Back Pain - FPIN's Clinical Inquiries - American Family Physician

Jul 15, 2018 - There is some evidence that early physical therapy may decrease posttreatment health care utilization for low back pain.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/0715/p115.html

Antibiotic Prophylaxis for COPD Exacerbations - FPIN's Clinical Inquiries - American ...

Apr 15, 2018 - Prophylactic antibiotics may be used to reduce the overall rate of COPD exacerbations and delay their onset. However, the appropriate antibiotic regimen and target population are unclear.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/0415/p527.html

Diabetes Education and Glycemic Control - FPIN's Clinical Inquiries - American Family ...

Feb 15, 2018 - Counseling by a diabetes educator or a team of educators delivered in a variety of formats may reduce A1C levels by 0.2% to 0.8% compared with usual care alone. Diabetes educators should be considered for patients who have higher baseline A1C levels (8% to 9%) because this group had ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2018/0215/p269.html

Rivaroxaban vs. Warfarin for Treatment of DVT and PE - FPIN's Clinical Inquiries - ...

Oct 15, 2017 - Rivaroxaban, along with the other factor Xa inhibitors, is as effective as or better in the short term (three months) than warfarin (Coumadin) for preventing recurrent DVT, nonfatal PE, and fatal PE, with no differences in mortality or bleeding events.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2017/1015/p532.html

Treatment for Calcaneal Apophysitis - FPIN's Clinical Inquiries - American Family ...

Jul 15, 2017 - Several treatments for calcaneal apophysitis may produce modest short-term improvements in pain scores. Heel inserts and prefabricated orthotics may initially improve pain scores and dysfunction, but patients have equal improvement by three months with or without therapy.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2017/0715/p126.html

Iron Deficiency in Heart Failure - FPIN's Clinical Inquiries - American Family Physician

Apr 15, 2017 - Treatment of iron deficiency in patients with heart failure using intravenous iron improves function, fatigue, and quality of life, and decreases risk of hospitalizations compared with placebo.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2017/0415/p514.html

Risk of Gout with the Use of Thiazide Diuretics - FPIN's Clinical Inquiries - American ...

Oct 1, 2015 - Thiazide diuretics may be used in most patients with hypertension who have only minimally increased risk of gout.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/1001/p622.html

Treatments for Sciatica - FPIN's Clinical Inquiries - American Family Physician

May 1, 2015 - Surgical diskectomy can be offered to patients with refractory sciatica, but there is only modest, short-term improvement in leg pain and disability scores. Epidural steroid injections may be offered to patients with sciatica of more than six months' duration.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0501/p612.html

Antidepressants for the Treatment of Insomnia in Patients with Depression - FPIN's ...

Nov 1, 2011 - There is no single antidepressant or class of antidepressants that is most effective for the treatment of insomnia in patients with depression. The use of antidepressant medications can have a positive impact on sleep physiology, but does not seem to improve subjective ratings of sleep ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2011/1101/od1.html

Micronutrient Supplementation During Pregnancy - FPIN's Clinical Inquiries - American ...

Aug 1, 2015 - A multimicronutrient supplement is an oral tablet containing the recommended daily allowance of several vitamins and minerals. The World Health Organization does not recommend multimicronutrient supplementation because of the potential for increased neonatal mortality in some situations.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0801/p222.html

Management of Acute Achilles Tendon Rupture - FPIN's Clinical Inquiries - American ...

Jun 1, 2015 - There are no clear evidence-based criteria to decide which patients should undergo operative vs. nonoperative management of acute Achilles tendon rupture.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0601/p794.html

Medications for Treatment of Interstitial Cystitis - FPIN's Clinical Inquiries - ...

Jan 15, 2015 - There are no long-term clinically effective oral medications. Pentosan (Elmiron) can improve overall symptom scores for interstitial cystitis over three to six months, but it does not improve scores for any of three individual symptoms (dysuria, urgency, frequency) compared with placebo.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2015/0115/p116.html

Surgical Treatment for Asymptomatic Cholelithiasis - FPIN's Clinical Inquiries - ...

Mar 15, 2014 - Surgery should not be offered to patients with asymptomatic cholelithiasis. Cholecystectomy may be beneficial for patients who are at high risk of biliary cancer, infection, or other complications, including younger patients and those with choledocholithiasis, sickle cell disease, ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0315/p468.html

Prostaglandins to Induce Labor in Women with Asthma - FPIN's Clinical Inquiries - ...

Sep 15, 2014 - There is little evidence evaluating whether prostaglandins used to induce labor increase the risk of bronchospasm in patients with asthma. The use of dinoprostone to induce labor is not associated with asthma exacerbations or reduced oxygen saturation in patients with active asthma or a...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0915/p415.html

Topical Preparations for Wound Healing - FPIN's Clinical Inquiries - American Family ...

Jun 15, 2014 - Topical silver should not be used for treatment of nonburn wounds because it does not hasten healing. Medical-grade topical honey can be used to reduce healing time for partial-thickness burns, but it produces no effect on lacerations, surgical wounds, chronic wounds, or vascular ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0615/p978.html

Intra-articular Corticosteroid Injections for Osteoarthritis of the Knee - FPIN's ...

Jul 15, 2014 - Intra-articular corticosteroid injections can be used to reduce pain by about 20% in the short term (one to three weeks) in patients with osteoarthritis of the knee.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2014/0715/p115.html

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