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Hyperlipidemia - American Family Physician

May 1, 2019 - This collection features AFP content on hyperlipidemia and related issues, including dyslipidemia, hypercholesterolemia, hypertriglyceridemia, kidney disease, lipid disorders, metabolic syndrome, statins, and triglyceride levels. This collection features AFP content on hyperlipidemia ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=13

Hyperlipidemia: Drugs for Cardiovascular Risk Reduction in Adults - American Family ...

Jan 15, 2017 - Guidelines from the American College of Cardiology/American Heart Association (ACC/AHA) and the U.K. National Institute for Health and Care Excellence (NICE) indicate that lipid-lowering drugs have benefit for primary and secondary prevention of atherosclerotic cardiovascular disease ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0115/p78.html

Statins in Persons at Low Risk of Cardiovascular Disease - Medicine by the Numbers - ...

Nov 1, 2017 - Despite the small reductions in nonfatal heart attacks and strokes, statins were not associated with a reduction in serious illness overall.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/1101/od1.html

Management of Hypertriglyceridemia - American Family Physician

May 1, 2007 - Hypertriglyceridemia is associated with an increased risk of cardiovascular events and acute pancreatitis. Along with lowering low-density lipoprotein cholesterol levels and raising high-density lipoprotein cholesterol levels, lowering triglyceride levels in high-risk patients (e.g., ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0501/p1365.html

Diet and Exercise in the Management of Hyperlipidemia - American Family Physician

May 1, 2010 - Dietary factors that influence lipid levels include modification of nutritional components, consumption of specific foods, use of food additives and supplements, and major dietary approaches. The most beneficial changes result from reducing intake of saturated and trans fats; increasing...

American Family Physician : Article

https://www.aafp.org/afp/2010/0501/p1097.html

Statin Use for the Primary Prevention of Cardiovascular Disease in Adults: ...

Jan 15, 2017 - The USPSTF recommends that adults without a history of cardiovascular disease (CVD) (i.e., symptomatic coronary artery disease or ischemic stroke) use a low- to moderate-dose statin for the prevention of CVD events and mortality when all of the following criteria are met: (1) they are ...

American Family Physician : U.S. Preventive Services Task Force

https://www.aafp.org/afp/2017/0115/od1.html

Should Family Physicians Follow the New ACC/AHA Cholesterol Treatment Guideline? Not ...

Aug 15, 2014 - The recommendations should have paid more attention to the inherent uncertainties in risk estimates and the importance of individual patient circumstances and preferences.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2014/0815/p223.html

Should Family Physicians Follow the New ACC/AHA Cholesterol Treatment Guideline? Yes: ...

Aug 15, 2014 - The recommendations appropriately focus treatment on those most likely to benefit.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2014/0815/p212.html

Omega-3 Fatty Acids - American Family Physician

Jul 1, 2004 - Omega-3 fatty acids have been shown to significantly reduce the risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with known coronary heart disease. Fatty fish, such as salmon and tuna, and fish oil are rich sources of the omega-3 fatty acids ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0701/p133.html

Metabolic Syndrome: Time for Action - American Family Physician

Jun 15, 2004 - The constellation of dyslipidemia (hypertriglyceridemia and low levels of high-density lipoprotein cholesterol), elevated blood pressure, impaired glucose tolerance, and central obesity is identified now as metabolic syndrome, also called syndrome X. Soon, metabolic syndrome will ...

American Family Physician : Article

https://www.aafp.org/afp/2004/0615/p2875.html

Omega-3 Fatty Acids and Cardiovascular Disease - Implementing AHRQ Effective Health ...

May 1, 2018 - What is the effect of omega-3 fatty acid supplementation on cardiovascular outcomes?

American Family Physician : Implementing AHRQ Effective Health Care Reviews

https://www.aafp.org/afp/2018/0501/p562.html

Should Family Physicians Routinely Screen for Hypercholesterolemia in Children? Yes: ...

Oct 15, 2012 - Yes: The Evidence Supports Universal Screening. Atherosclerotic cardiovascular disease events are the culmination of a process that has clearly been shown to begin in childhood, with accumulation of abnormal lipids in the vascular intima.

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2012/1015/od2.html

Optimal Management of Cholesterol Levels and the Prevention of Coronary Heart Disease ...

Jan 15, 2002 - Coronary heart disease, the leading cause of death in women, is largely preventable. Lifestyle modifications (e.g., diet and exercise) are the cornerstone of primary and secondary prevention. Elevated levels of low-density lipoprotein cholesterol and triglycerides and low levels of ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0115/p217.html

Evolocumab (Repatha) for the Treatment of Hyperlipidemia - STEPS - American Family ...

Nov 15, 2016 - Evolocumab is generally safe and effective at lowering serum LDL cholesterol levels for select patients who need marked cholesterol reduction and can tolerate injections. However, it remains unknown whether evolocumab prevents premature death from cardiovascular events.

American Family Physician : STEPS

https://www.aafp.org/afp/2016/1115/p843.html

For Hyperlipidemia, Go Where the Evidence Takes You: Give a Statin and Nothing Else - ...

Nov 1, 2010 - Only statins have patient-oriented evidence supporting their role in reducing all-cause mortality. The NCEP–ATP III guidelines offer a nine-step approach for reaching target lipid levels, but the application to everyday practice is far simpler: If a patient with hyperlipidemia has ...

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2010/1101/p1063.html

The Role of Nonstatin Therapy in Managing Hyperlipidemia - Editorials: Controversies in...

Nov 1, 2010 - When treating hyperlipidemia, physicians often face the question of the clinical value of nonstatin drugs, including bile acid sequestrants, fibrates (fibric acid derivatives), niacin, and cholesterol-absorption inhibitors. This editorial highlights the most prominent trial data and ...

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2010/1101/p1056.html

Cholesterol Treatment Guidelines Update - American Family Physician

Mar 1, 2002 - Hypercholesterolemia is one of the major contributors to atherosclerosis and coronary heart disease in our society. The National Cholesterol Education Program of the National Institutes of Health has created a set of guidelines that standardize the clinical assessment and management of ...

American Family Physician : Article

https://www.aafp.org/afp/2002/0301/p871.html

Treatment of Cholesterol Abnormalities - American Family Physician

Mar 15, 2005 - Cardiovascular disease and its subset coronary heart disease are leading causes of morbidity and mortality in the United States and worldwide. In general, higher levels of low-density lipoprotein cholesterol are associated with an increased risk of coronary heart disease, myocardial ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0315/p1137.html

Niacin Does Not Decrease Mortality in Patients with Coronary Artery Disease or Low HDL ...

Jul 15, 2017 - We are now flush with data about the effects of niacin in patients with elevated cholesterol levels. Despite its ability to raise high-density lipoprotein (HDL) serum cholesterol levels, it does not add additional mortality or morbidity benefit to statin treatment. Patients with ...

American Family Physician : POEMs

https://www.aafp.org/afp/2017/0715/p129.html

Should We Treat Moderately Elevated Triglycerides? No: Reducing Moderately Elevated ...

Feb 1, 2011 - Moderately elevated triglyceride levels have not been established as an independent risk factor for CHD. More importantly, the lowering of moderately elevated triglyceride levels with drug therapy has not been shown to decrease the rate of CHD for primary prevention in otherwise healthy...

American Family Physician : Editorials: Controversies in Family Medicine

https://www.aafp.org/afp/2011/0201/p246.html

Statins Ineffective for Primary Prevention of Cardiovascular Disease in Patients 75 ...

Apr 1, 2019 - In this retrospective study, statin treatment in patients 75 years or older without preexisting CVD did not change the likelihood of developing CVD or reduce any-cause mortality. However, patients 75 to 84 years of age with diabetes mellitus benefitted from treatment. These results ...

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0401/p461.html

Statins for Primary Cardiovascular Prevention - Cochrane for Clinicians - American ...

Oct 1, 2011 - Trials to date have found that statins reduce all-cause mortality, composite cardiovascular outcomes, and revascularization. However, most trials included large numbers of persons with known CVD. Clear evidence of the effectiveness of statins to prevent a first cardiovascular event is ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/1001/p767.html

The JUPITER Study: Biomarkers Plus Statin vs. Lifestyle Modification for Preventing ...

Mar 15, 2009 - ...COLIN KOPES-KERR, MD, Santa Rosa Family Medicine Residency, Santa Rosa, California MARK EBELL, MD, MS, University of Georgia, Athens, Georgia Am Fam Physician. 2009 Mar 15;79(6):438-442. The JUPITER (Justification for the Use of Statins in Prevention: An Intervention Trial...

American Family Physician : Editorials

https://www.aafp.org/afp/2009/0315/p438.html

Statins for Non-Dialysis Chronic Kidney Disease - Cochrane for Clinicians - American ...

Jan 1, 2010 - When taken over a five-year period, statins significantly reduce all-cause mortality (number needed to treat [NNT] = 56), cardiovascular mortality (NNT = 86), and nonfatal cardiovascular events (NNT = 25).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2010/0101/p27.html

Best Alternatives to Statins for Treating Hyperlipidemia - FPIN's Clinical Inquiries - ...

Oct 1, 2007 - Most alternatives to statin therapy reduce cholesterol levels but do not consistently demonstrate a reduction in cardiac-related and all-cause mortality in patients with or without coronary heart disease (CHD). Fibrates and niacin decrease the risk of major coronary events; however, no ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2007/1001/p1027.html

ACP Releases Guideline on Lipid Control in Patients with Type 2 Diabetes Mellitus - ...

Aug 15, 2004 - A guideline on the management of dyslipidemia, particularly hypercholesterolemia, in patients with type 2 diabetes mellitus has been published by the Clinical Efficacy Assessment Subcommittee of the American College of Physicians (ACP).

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2004/0815/p775.html

U.S. Statin Guidelines: Expensive but Not Necessarily Effective - Editorials - American...

May 15, 2007 - ...HENRY C. BARRY, MD, MS, Michigan State University College of Human Medicine, East Lansing, Michigan JEROME R. HOFFMAN, MD, MA, David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, California Am Fam Physician. 2007 May 15;75(10):1453-1459....

American Family Physician : Editorials

https://www.aafp.org/afp/2007/0515/p1453.html

Statin Therapy in Patients with Type 2 Diabetes - FPIN's Clinical Inquiries - American ...

Sep 1, 2005 - Based on current evidence, statin therapy should be offered to all patients with type 2 diabetes who are known to have coronary artery disease.

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2005/0901/p866.html

Improvment in Current Approaches to Lipid Lowering - Editorials - American Family ...

Mar 1, 2002 - ...BENJAMIN J. ANSELL, M.D., University of California, Los Angeles, School of Medicine Los Angeles, California Am Fam Physician. 2002 Mar 1;65(5):783-787. Related Article The National Cholesterol Education Program (NCEP) has updated its recommendations for cholesterol screening and...

American Family Physician : Editorials

https://www.aafp.org/afp/2002/0301/p783.html

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