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Differential Diagnosis of Polyarticular Arthritis - American Family Physician

Jul 1, 2015 - Polyarticular arthritis is commonly encountered in clinical settings and has multiple etiologies. The first step is to distinguish between true articular pain and nonarticular or periarticular conditions by recognizing clinical patterns through the history and physical examination. Once...

American Family Physician : Article

https://www.aafp.org/afp/2015/0701/p35.html

Syncope: Evaluation and Differential Diagnosis - American Family Physician

Mar 1, 2017 - Syncope is an abrupt and transient loss of consciousness caused by cerebral hypoperfusion. It accounts for 1% to 1.5% of emergency department visits, resulting in high hospital admission rates and significant medical costs. Syncope is classified as neurally mediated, cardiac, and ...

American Family Physician : Article

https://www.aafp.org/afp/2017/0301/p303.html

Evaluation of the Patient with Hip Pain - American Family Physician

Jan 1, 2014 - Hip pain is a common and disabling condition that affects patients of all ages. The differential diagnosis of hip pain is broad, presenting a diagnostic challenge. Patients often express that their hip pain is localized to one of three anatomic regions: the anterior hip and groin, the ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0101/p27.html

Evaluation of Patients with Leukocytosis - American Family Physician

Dec 1, 2015 - An elevated white blood cell count has many potential etiologies, including malignant and nonmalignant causes. It is important to use age- and pregnancy-specific normal ranges for the white blood cell count. A repeat complete blood count with peripheral smear may provide helpful ...

American Family Physician : Article

https://www.aafp.org/afp/2015/1201/p1004.html

Palpitations: Evaluation in the Primary Care Setting - American Family Physician

Dec 15, 2017 - Palpitations are a common problem in the ambulatory primary care setting, and cardiac causes are the most concerning etiology. Psychiatric illness, adverse effects of prescription and over-the-counter medications, and substance use should also be considered. Distinguishing cardiac from ...

American Family Physician : Article

https://www.aafp.org/afp/2017/1215/p784.html

Assessment of Asymptomatic Microscopic Hematuria in Adults - American Family Physician

Dec 1, 2013 - Although routine screening for bladder cancer is not recommended, microscopic hematuria is often incidentally discovered by primary care physicians. The American Urological Association has published an updated guideline for the management of asymptomatic microscopic hematuria, which is ...

American Family Physician : Article

https://www.aafp.org/afp/2013/1201/p747.html

Somatic Symptom Disorder - American Family Physician

Jan 1, 2016 - With the release of the Diagnostic and Statistical Manual of Mental Disorders, 5th ed., the diagnostic category previously known as somatoform disorders is now called somatic symptom and related disorders. The revisions were intended to increase their relevance in the primary care ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0101/p49.html

First Trimester Bleeding: Evaluation and Management - American Family Physician

Feb 1, 2019 - Approximately one-fourth of pregnant women will experience bleeding in the first trimester. The differential diagnosis includes threatened abortion, early pregnancy loss, and ectopic pregnancy. Pain and heavy bleeding are associated with an increased risk of early pregnancy loss. ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0201/p166.html

Hyperhidrosis: Management Options - American Family Physician

Jun 1, 2018 - Hyperhidrosis is excessive sweating that affects patients’ quality of life, resulting in social and work impairment and emotional distress. Primary hyperhidrosis is bilaterally symmetric, focal, excessive sweating of the axillae, palms, soles, or craniofacial region not caused by other ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0601/p729.html

Evaluation and Management of Orthostatic Hypotension - American Family Physician

Sep 1, 2011 - Orthostatic hypotension is defined as a decrease in systolic blood pressure of 20 mm Hg or a decrease in diastolic blood pressure of 10 mm Hg within three minutes of standing when compared with blood pressure from the sitting or supine position. It results from an inadequate physiologic...

American Family Physician : Article

https://www.aafp.org/afp/2011/0901/p527.html

Clinical Evaluation of Bleeding and Bruising in Primary Care - American Family Physician

Feb 15, 2016 - Bleeding and bruising are common symptoms in the primary care setting. The patient history can help determine whether the bruising or bleeding is abnormal. The International Society on Thrombosis and Hemostasis has developed a bleeding assessment tool that can be used to indicate ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0215/p279.html

Epistaxis: Outpatient Management - American Family Physician

Aug 15, 2018 - Epistaxis is a common emergency encountered by primary care physicians. Up to 60% of the general population experience epistaxis, and 6% seek medical attention for it. More than 90% of cases arise from the anterior nasal circulation, and most treatments can be easily performed in the ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0815/p240.html

Diagnostic Approach to Patients with Tinnitus - American Family Physician

Jan 15, 2014 - Tinnitus, a common symptom encountered in family medicine, is defined as the perception of noise in the absence of an acoustic stimulus outside of the body. Because tinnitus is a symptom and not a disease, its underlying cause must be determined to best help patients. Although tinnitus ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0115/p106.html

Hirsutism in Women - American Family Physician

Aug 1, 2019 - Hirsutism is the excessive growth of terminal hair in a typical male pattern in a female. It is often a sign of excessive androgen levels. Although many conditions can lead to hirsutism, polycystic ovary syndrome and idiopathic hyperandrogenism account for more than 85% of cases. Less ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0801/p168.html

The Generalized Rash: Part I. Differential Diagnosis - American Family Physician

Mar 15, 2010 - Physicians often have difficulty diagnosing a generalized rash because many different conditions produce similar rashes, and a single condition can result in different rashes with varied appearances. A rapid and accurate diagnosis is critically important to make treatment decisions, ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0315/p726.html

Evaluation and Diagnosis of Wrist Pain: A Case-Based Approach - American Family Physician

Apr 15, 2013 - Patients with wrist pain commonly present with an acute injury or spontaneous onset of pain without a definite traumatic event. A fall onto an outstretched hand can lead to a scaphoid fracture, which is the most commonly fractured carpal bone. Conventional radiography alone can miss up ...

American Family Physician : Article

https://www.aafp.org/afp/2013/0415/p568.html

Chronic Pelvic Pain in Women - American Family Physician

Mar 1, 2016 - Chronic pelvic pain in women is defined as persistent, noncyclic pain perceived to be in structures related to the pelvis and lasting more than six months. Often no specific etiology can be identified, and it can be conceptualized as a chronic regional pain syndrome or functional ...

American Family Physician : Article

https://www.aafp.org/afp/2016/0301/p380.html

Evaluation and Treatment of Constipation in Children and Adolescents - American Family ...

Jul 15, 2014 - Childhood constipation is common and almost always functional without an organic etiology. Stool retention can lead to fecal incontinence in some patients. Often, a medical history and physical examination are sufficient to diagnose functional constipation. Further evaluation for ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0715/p82.html

Diagnostic Imaging of Acute Abdominal Pain in Adults - American Family Physician

Apr 1, 2015 - Acute abdominal pain is a common presentation in the outpatient setting and can represent conditions ranging from benign to life-threatening. If the patient history, physical examination, and laboratory testing do not identify an underlying cause of pain and if serious pathology remains...

American Family Physician : Article

https://www.aafp.org/afp/2015/0401/p452.html

Evaluation of Scrotal Masses - American Family Physician

May 1, 2014 - Scrotal masses are caused by a variety of disorders, ranging from benign conditions to those requiring emergent surgical intervention. Painful scrotal masses require urgent evaluation. Characteristics that suggest testicular torsion include rapid symptom onset, nausea and vomiting, high...

American Family Physician : Article

https://www.aafp.org/afp/2014/0501/p723.html

Evaluation of the Patient with Chronic Cough - American Family Physician

Oct 15, 2011 - Initial evaluation of the patient with chronic cough (i.e., of more than eight weeks’ duration) should include a focused history and physical examination, and in most patients, chest radiography. Patients who are taking an angiotensin-converting enzyme inhibitor should switch to a ...

American Family Physician : Article

https://www.aafp.org/afp/2011/1015/p887.html

Evaluation of Nausea and Vomiting: A Case-Based Approach - American Family Physician

Sep 15, 2013 - In the absence of acute abdominal pain, significant headache, or recent initiation of certain medications, acute nausea and vomiting is usually the result of self-limited gastrointestinal infections. Nausea and vomiting is also a common adverse effect of radiation therapy, chemotherapy,...

American Family Physician : Article

https://www.aafp.org/afp/2013/0915/p371.html

Ear and Hearing Disorders - American Family Physician

Sep 15, 2019 - This collection features AFP content on ear and hearing disorders and related issues, including hearing loss, otitis externa, otitis media, and tinnitus. This collection features AFP content on ear and hearing disorders and related issues, including hearing loss, otitis ...

American Family Physician : AFP By Topic

https://www.aafp.org/afp/topicModules/viewTopicModule.htm?topicModuleId=98

Diagnostic Approach to Chronic Constipation in Adults - American Family Physician

Aug 1, 2011 - Constipation is traditionally defined as three or fewer bowel movements per week. Risk factors for constipation include female sex, older age, inactivity, low caloric intake, low-fiber diet, low income, low educational level, and taking a large number of medications. Chronic ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0801/p299.html

Update on the Evaluation and Management of Functional Dyspepsia - American Family ...

Mar 1, 2011 - Dyspepsia affects up to 40 percent of adults each year and is often diagnosed as functional (nonulcer) dyspepsia. The defining symptoms are postprandial fullness, early satiation, or epigastric pain or burning in the absence of causative structural disease. These symptoms may coexist ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0301/p547.html

Evaluation of Syncope - American Family Physician

Sep 15, 2011 - Syncope is a transient and abrupt loss of consciousness with complete return to preexisting neurologic function. It is classified as neurally mediated (i.e., carotid sinus hypersensitivity, situational, or vasovagal), cardiac, orthostatic, or neurogenic. Older adults are more likely to ...

American Family Physician : Article

https://www.aafp.org/afp/2011/0915/p640.html

Diagnosing the Cause of Chest Pain - American Family Physician

Nov 15, 2005 - Chest pain presents a diagnostic challenge in outpatient family medicine. Noncardiac causes are common, but it is important not to overlook serious conditions such as an acute coronary syndrome, pulmonary embolism, or pneumonia. In addition to a thorough history and physical ...

American Family Physician : Article

https://www.aafp.org/afp/2005/1115/p2012.html

Evaluation of the Patient with Muscle Weakness - American Family Physician

Apr 1, 2005 - Muscle weakness is a common complaint among patients presenting to family physicians. Diagnosis begins with a patient history distinguishing weakness from fatigue or asthenia, separate conditions with different etiologies that can coexist with, or be confused for, weakness. The pattern ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0401/p1327.html

Treatment of Constipation in Older Adults - American Family Physician

Dec 1, 2005 - Constipation is a common complaint in older adults. Although constipation is not a physiologic consequence of normal aging, decreased mobility and other comorbid medical conditions may contribute to its increased prevalence in older adults. Functional constipation is diagnosed when no ...

American Family Physician : Article

https://www.aafp.org/afp/2005/1201/p2277.html

Approach to the Adult Patient with Fever of Unknown Origin - American Family Physician

Dec 1, 2003 - Fever of unknown origin (FUO) in adults is defined as a temperature higher than 38.3 degrees C (100.9 degrees F) that lasts for more than three weeks with no obvious source despite appropriate investigation. The four categories of potential etiology of FUO are classic, nosocomial, ...

American Family Physician : Article

https://www.aafp.org/afp/2003/1201/p2223.html

Management of Erectile Dysfunction - American Family Physician

Feb 1, 2010 - Erectile dysfunction (ED) is the most common sexual problem in men. The incidence increases with age and affects up to one third of men throughout their lives. It causes a substantial negative impact on intimate relationships, quality of life, and self-esteem. History and physical ...

American Family Physician : Article

https://www.aafp.org/afp/2010/0201/p305.html

Bleeding and Bruising: A Diagnostic Work-up - American Family Physician

Apr 15, 2008 - Primary care physicians are often asked about easy bruising, excessive bleeding, or risk of bleeding before surgery. A thorough history, including a family history, will guide the appropriate work-up, and a physical examination may provide clues to diagnosis. A standardized bleeding ...

American Family Physician : Article

https://www.aafp.org/afp/2008/0415/p1117.html

Evaluation and Treatment of Constipation in Infants and Children - American Family ...

Feb 1, 2006 - Constipation in children usually is functional and the result of stool retention. However, family physicians must be alert for red flags that may indicate the presence of an uncommon but serious organic cause of constipation, such as Hirschsprung's disease (congenital aganglionic ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0201/p469.html

Diagnosis of Acute Abdominal Pain in Older Patients - American Family Physician

Nov 1, 2006 - Acute abdominal pain is a common presenting complaint in older patients. Presentation may differ from that of the younger patient and is often complicated by coexistent disease, delays in presentation, and physical and social barriers. The physical examination can be misleadingly ...

American Family Physician : Article

https://www.aafp.org/afp/2006/1101/p1537.html

Evaluation of Back Pain in Children and Adolescents - American Family Physician

Dec 1, 2007 - Back pain is fairly prevalent in healthy children and adolescents. When children or adolescents seek medical care for back pain, it is highly likely that underlying pathology will be identified. Common causes of back pain include nonspecific pain or muscle strain, herniated disk, ...

American Family Physician : Article

https://www.aafp.org/afp/2007/1201/p1669.html

Lymphadenopathy and Malignancy - American Family Physician

Dec 1, 2002 - The majority of patients presenting with peripheral lymphadenopathy have easily identifiable causes that are benign or self-limited. Among primary care patients presenting with lymphadenopathy, the prevalence of malignancy has been estimated to be as low as 1.1 percent. The critical ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1201/p2103.html

Diagnostic Approach to Polyarticular Joint Pain - American Family Physician

Sep 15, 2003 - Identifying the cause of polyarticular joint pain can be difficult because of the extensive differential diagnosis. A thorough history and a complete physical examination are essential. Six clinical factors are helpful in narrowing the possible causes: disease chronology, inflammation, ...

American Family Physician : Article

https://www.aafp.org/afp/2003/0915/p1151.html

Evaluating the Febrile Patient with a Rash - American Family Physician

Aug 15, 2000 - The differential diagnosis for febrile patients with a rash is extensive. Diseases that present with fever and rash are usually classified according to the morphology of the primary lesion. Rashes can be categorized as maculopapular (centrally and peripherally distributed), petechial, ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0815/p804.html

Evaluating Fever of Unidentifiable Source in Young Children - American Family Physician

Jun 15, 2007 - Most children will have been evaluated for a febrile illness by 36 months of age. Although the majority will have a self-limited viral illness, studies done before the use of Haemophilus influenzae type b and Streptococcus pneumoniae vaccines showed that approximately 10 percent of ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0615/p1805.html

ACP Provides Guidance on Nonsurgical Treatment of Urinary Incontinence in Women - ...

Jun 1, 2015 - The American College of Physicians (ACP) has provided recommendations for nonsurgical treatment of UI in women. Treatment of UI is aimed at achieving, or at least improving, symptoms. It is deemed effective if it reduces the number of episodes by at least one-half.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2015/0601/p801.html

Prasterone (Intrarosa) for Dyspareunia - STEPS - American Family Physician

Jan 15, 2019 - Prasterone is similarly effective to nonprescription options for treating vaginal dryness and itching associated with menopause and may offer a small benefit in the treatment of dyspareunia.

American Family Physician : STEPS

https://www.aafp.org/afp/2019/0115/p117.html

Radiologic Evaluation of Acute Chest Pain—Suspected Myocardial Ischemia - American ...

Aug 15, 2007 - The American College of Radiology has developed appropriateness criteria for a number of clinical conditions and procedures. Criteria are available on imaging tests used in the evaluation of acute chest pain--suspected myocardial ischemia. Imaging tests for a suspected cardiac etiology ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0815/p533.html

Second-Generation H1-Antihistamines for Chronic Spontaneous Urticaria - Cochrane for ...

Sep 1, 2016 - There is good evidence that second-generation H1-antihistamines are helpful in the short- and intermediate-term suppression of urticaria. Cetirizine (Zyrtec) in a dosage of 10 mg daily is effective at completely suppressing symptoms of chronic spontaneous urticaria (number needed to ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0901/p352.html

Anterior Hip Pain - American Family Physician

Oct 15, 1999 - Anterior hip pain is a common complaint with many possible causes. Apophyseal avulsion and slipped capital femoral epiphysis should not be overlooked in adolescents. Muscle and tendon strains are common in adults. Subsequent to accurate diagnosis, strains should improve with rest and ...

American Family Physician : Article

https://www.aafp.org/afp/1999/1015/p1687.html

Urinary Incontinence in Women: Evaluation and Management - American Family Physician

Dec 1, 2000 - Because the prevalence of urinary incontinence increases with age, a working knowledge of the diagnosis and treatment of the various types of urinary incontinence is fundamental to the care of women. As the population of the United States ages, primary care physicians can expect to see ...

American Family Physician : Article

https://www.aafp.org/afp/2000/1201/p2433.html

Beta2 Agonists for Acute Cough or a Clinical Diagnosis of Acute Bronchitis - Cochrane ...

May 1, 2017 - There is insufficient evidence to determine whether beta2 agonists can improve symptoms for children with acute cough or bronchitis with wheeze. Beta2 agonists are not likely to benefit and may cause adverse effects in adults who do not have evidence of airflow restriction (number ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2017/0501/p551.html

A Primary Care Approach to the Patient with Claudication - American Family Physician

Feb 15, 2000 - Peripheral arterial occlusive disease occurs in about 18 percent of persons over 70 years of age. Usually, patients who have this disease present with intermittent claudication with pain in the calf, thigh or buttock that is elicited by exertion and relieved with a few minutes of rest. ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0215/p1027.html

Quinine for Leg Cramps - Cochrane for Clinicians - American Family Physician

Feb 1, 2016 - Quinine is moderately effective in decreasing the frequency and intensity of muscle cramps, but it is also associated with an increase in minor adverse effects. In addition, there is a risk of rare but serious adverse effects.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2016/0201/p177.html

Antibiotics for Sore Throat - Cochrane for Clinicians - American Family Physician

Jul 1, 2014 - Compared with placebo, antibiotics can shorten the duration of sore throat symptoms by about 16 hours and can reduce complications. In countries where the absolute rates of complications are higher, antibiotic therapy is more likely to be effective. The effectiveness of antibiotic ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2014/0701/p23.html

Hip Pain in Athletes - American Family Physician

Apr 1, 2000 - Hip pain in athletes involves a wide differential diagnosis. Adolescents and young adults are at particular risk for various apophyseal and epiphyseal injuries due to lack of ossification of these cartilaginous growth plates. Older athletes are more likely to present with tendinitis in ...

American Family Physician : Article

https://www.aafp.org/afp/2000/0401/p2109.html

Evaluation and Treatment of Galactorrhea - American Family Physician

May 1, 2001 - Galactorrhea, or inappropriate lactation, is a relatively common problem that occurs in approximately 20 to 25 percent of women. Lactation requires the presence of estrogen, progesterone and, most importantly, prolactin. Stress, suckling, sleep, sexual intercourse and medications may ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0501/p1763.html

Management of Common Symptoms in Terminally Ill Patients: Part I. Fatigue, Anorexia, ...

Sep 1, 2001 - Physical symptoms other than pain often contribute to suffering near the end of life. In addition to pain, the most common symptoms in the terminal stages of an illness such as cancer or acquired immunodeficiency syndrome are fatigue, anorexia, cachexia, nausea, vomiting, constipation, ...

American Family Physician : Article

https://www.aafp.org/afp/2001/0901/p807.html

Evaluation of Clumsiness in Children - American Family Physician

Oct 15, 2002 - Parents and physicians often dismiss seemingly minor motor difficulties in children. Approximately 6 percent of school-aged children have coordination problems serious enough to interfere with academic performance and social integration. These problems often arise during the early ...

American Family Physician : Article

https://www.aafp.org/afp/2002/1015/p1435.html

Gluten Is Not the Culprit in Many Patients’ Symptoms - POEMs - American Family Physician

May 1, 2016 - Gluten may not be the cause of gastrointestinal symptoms in many patients with nonceliac gluten sensitivity. Only one-third of patients on a gluten-free diet experienced symptoms and correctly identified when they were given gluten-containing flour. Almost one-half (49%) of patients ...

American Family Physician : POEMs

https://www.aafp.org/afp/2016/0501/p788.html

Constipation in the Elderly - American Family Physician

Sep 15, 1998 - Constipation affects as many as 26 percent of elderly men and 34 percent of elderly women and is a problem that has been related to diminished perception of quality of life. Constipation may be the sign of a serious problem such as a mass lesion, the manifestation of a systemic disorder...

American Family Physician : Article

https://www.aafp.org/afp/1998/0915/p907.html

A Simple Cough Algorithm for Children with Chronic Cough - POEMs - American Family ...

Nov 15, 2013 - In children with chronic cough, a simple approach of ruling out specific indicators of cause, followed by treating a wet cough with antibiotics, results in a significant decrease in the duration of cough. Some of the causes of chronic cough were reactive airway disease, bronchiectasis, ...

American Family Physician : POEMs

https://www.aafp.org/afp/2013/1115/od1.html

Is the San Francisco Syncope Rule Reliable? - AFP Journal Club - American Family Physician

Sep 15, 2009 - Can the San Francisco Syncope Rule successfully determine which patients can be safely discharged after an acute syncopal episode? External validation suggests that the sensitivity of the rule is lower than first reported. Physicians need to apply their clinical acumen and override the ...

American Family Physician : AFP Journal Club

https://www.aafp.org/afp/2009/0915/p558.html

ACCP Releases Statement on Dyspnea Treatment in Patients with Advanced Lung or Heart ...

Oct 15, 2010 - The American College of Chest Physicians (ACCP) wrote a consensus statement to influence clinical practice and provide suggestions regarding the management of dyspnea in patients with advanced lung or heart disease.

American Family Physician : Practice Guidelines

https://www.aafp.org/afp/2010/1015/p999.html

Psychological Interventions for Noncardiac Chest Pain - Cochrane for Clinicians - ...

Nov 1, 2005 - Noncardiac chest pain can be caused by gastroesophageal reflux disease (GERD), panic disorder, or a number of other psychological conditions. Psychotherapy, particularly cognitive behavior therapy, has been shown to reduce the number of days with chest pain significantly over a ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2005/1101/p1701.html

GERD Treatment for Chronic Nonspecific Cough in Children and Adults - Cochrane for ...

Sep 1, 2011 - Acid suppressants or prokinetic agents should not be used to treat chronic nonspecific cough in infants or children. There is insufficient evidence to support or discourage use of these agents to treat chronic non-specific cough in adults, even in those with a history of GERD.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2011/0901/p502.html

Syncope: Initial Evaluation and Prognosis - Point-of-Care Guides - American Family ...

Oct 15, 2006 - Although syncope often is benign, it may have a serious underlying cause. An important question for primary care or emergency department physicians is whether the patient can be evaluated safely in the outpatient setting.

American Family Physician : Point-of-Care Guides

https://www.aafp.org/afp/2006/1015/p1367.html

Do NSAIDs Help in Acute or Chronic Low Back Pain? - Cochrane for Clinicians - American ...

Apr 1, 2002 - Patients can expect a modest improvement in global function with NSAID therapy, such as ibuprofen. There is no evidence that any particular NSAID or combination of medicines has superior efficacy in the treatment of low back pain.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2002/0401/p1319.html

Low Back Pain - Clinical Evidence Handbook - American Family Physician

Mar 1, 2002 - What are the effects of oral drug treatments for low back pain? What are the effects of local injections for low back pain? What are the effects of nondrug treatments for low back pain?

American Family Physician : Clinical Evidence Handbook

https://www.aafp.org/afp/2002/0301/p925.html

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