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Medicine by the numbers

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Combined Hormonal Contraceptives for Heavy Menstrual Bleeding - Cochrane for Clinicians...

Dec 1, 2019 - Combined oral contraceptives decrease the number of women reporting menorrhagia over six months compared with placebo (absolute risk reduction = 36.7%; number needed to treat = 2.7).

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/1201/p677.html

Elagolix (Orilissa) for Endometriosis Pain - STEPS - American Family Physician

Oct 15, 2019 - Elagolix can decrease pain in women with endometriosis, but it is expensive and has adverse effects similar to those of other medications that decrease estrogen levels.

American Family Physician : STEPS

https://www.aafp.org/afp/2019/1015/p502.html

Misoprostol Alone is Associated with High Rate of Successful First-Trimester Abortion -...

Jul 15, 2019 - Misoprostol alone was associated with a nearly 80% success rate in the first trimester of pregnancy on meta-analysis.

American Family Physician : POEMs

https://www.aafp.org/afp/2019/0715/p119.html

Aromatase Inhibitors Such as Letrozole (Femara) vs. Clomiphene (Clomid) for Subfertile ...

May 1, 2019 - When treated with letrozole, subfertile women with PCOS who are trying to conceive have increased chances of pregnancy (number needed to treat [NNT] = 11) and live birth (NNT = 10) compared with those treated with clomiphene.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2019/0501/p545.html

Primary Care of Breast Cancer Survivors - American Family Physician

Mar 15, 2019 - With declining mortality rates, the number of breast cancer survivors is increasing. Ongoing care after breast cancer treatment is often provided by primary care physicians. This care includes surveillance for cancer recurrence with a history and physical examination every three to six ...

American Family Physician : Article

https://www.aafp.org/afp/2019/0315/p370.html

Prasterone (Intrarosa) for Dyspareunia - STEPS - American Family Physician

Jan 15, 2019 - Prasterone is similarly effective to nonprescription options for treating vaginal dryness and itching associated with menopause and may offer a small benefit in the treatment of dyspareunia.

American Family Physician : STEPS

https://www.aafp.org/afp/2019/0115/p117.html

Cervical Cancer: Evaluation and Management - American Family Physician

Apr 1, 2018 - Human papillomavirus infection is the precursor for the development of cervical cancer and is detectable in 99.7% of squamous cell carcinoma and adenocarcinoma cases. Early detection of precancerous lesions with Papanicolaou testing remains the primary mechanism for cancer prevention. ...

American Family Physician : Article

https://www.aafp.org/afp/2018/0401/p449.html

Oral NSAIDs for Perineal Pain in the Early Postpartum Period - Medicine by the Numbers ...

May 1, 2017 - Oral nonsteroidal anti-inflammatory drugs were able to adequately relieve perineal pain for many postpartum women at four hours and longer.

American Family Physician : Medicine by the Numbers

https://www.aafp.org/afp/2017/0501/od1.html

Conjugated Estrogens/Bazedoxifene (Duavee) for Menopausal Symptoms - STEPS - American ...

Feb 15, 2016 - Conjugated estrogens/bazedoxifene is effective for the treatment of menopausal symptoms and may be better tolerated than conjugated estrogens/medroxyprogesterone. It will maintain bone mineral density in the lumbar spine and hip, but its effect on fractures is not known. Cardiovascular ...

American Family Physician : STEPS

https://www.aafp.org/afp/2016/0215/p307.html

Options for Women with Unintended Pregnancy - American Family Physician

Apr 15, 2015 - Unintended pregnancy refers to unwanted, unplanned, or mistimed pregnancies. One-half of all pregnancies in the United States are unintended, and family physicians are often asked to provide counseling, support, and resources for women with unintended pregnancies. Options include ...

American Family Physician : Article

https://www.aafp.org/afp/2015/0415/p544.html

An Update on Emergency Contraception - American Family Physician

Apr 1, 2014 - Emergency contraception decreases the risk of unintended pregnancy after unprotected sexual intercourse or after suspected failure of routine contraception (e.g., a condom breaking). Oral methods include combined contraceptive pills (i.e., Yuzpe method), single- or split-dose ...

American Family Physician : Article

https://www.aafp.org/afp/2014/0401/p545.html

The Effects of Combination Contraceptives on Weight - Cochrane for Clinicians - ...

Dec 1, 2012 - Compared with placebo or no intervention, the use of combination contraceptives was not associated with weight gain. Most studies comparing different types of combination contraceptives showed no statistically significant effects on weight.

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2012/1201/p1009.html

Contraceptive Patch and Vaginal Ring vs. Combined Oral Contraceptives - Cochrane for ...

Aug 1, 2009 - Based on moderate quality evidence, contraceptive effectiveness of the vaginal ring or patch is similar to COC. Compliance is better with the patch, but its use is discontinued more often than COCs or the ring because of adverse effects. Vaginal ring and COC users have similar rates of ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2009/0801/p232.html

Effect of Antiepileptic Drugs on Oral Contraceptives - FPIN's Clinical Inquiries - ...

Sep 1, 2008 - We found no studies that measure, or even estimate, any increase in pregnancy rates in women taking antiepileptic drugs. Antiepileptic drugs known to induce the hepatic cytochrome P450 (CYP450) isoenzyme cause decreased sex hormone levels in women taking oral contraceptives, raising the...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2008/0901/p634.html

Levonorgestrel/Ethinyl Estradiol (Lybrel) for Continuous Contraception - STEPS - ...

Jan 15, 2008 - Lybrel appears to be as safe and effective as other combined oral contraceptives; however, at this time, there is little published data about this specific product. Other combined monophasic oral contraceptives, some of which cost less than Lybrel, can be used continuously and have been...

American Family Physician : STEPS

https://www.aafp.org/afp/2008/0115/p222.html

Treatment of Menorrhagia - American Family Physician

Jun 15, 2007 - Menorrhagia is defined as excessive uterine bleeding occurring at regular intervals or prolonged uterine bleeding lasting more than seven days. The classic definition of menorrhagia (i.e., greater than 80 mL of blood loss per cycle) is rarely used clinically. Women describe the loss or ...

American Family Physician : Article

https://www.aafp.org/afp/2007/0615/p1813.html

Risks and Benefits of Combination Contraceptives - FPIN's Clinical Inquiries - American...

Dec 1, 2006 - The risks of using oral combination contraceptives include: a three- to sixfold increase in the incidence of venous thromboembolism (VTE) apparent by the fourth month of use and highest between six and 12 months of use; a two- to sixfold increase in the risk of ischemic stroke among ...

American Family Physician : FPIN's Clinical Inquiries

https://www.aafp.org/afp/2006/1201/p1915.html

Initiating Hormonal Contraception - American Family Physician

Jul 1, 2006 - Most women can safely begin taking hormonal birth control products immediately after an office visit, at any point in the menstrual cycle. Because hormonal contraceptives do not accelerate cervical neoplasia or interfere with cervical cytology, women who have not had a recent ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0701/p105.html

Nonhormonal Therapies for Hot Flashes in Menopause - American Family Physician

Feb 1, 2006 - Numerous reports in the medical literature and popular media have discussed the effectiveness of various nonhormonal agents in reducing menopausal hot flash symptoms. Data for these therapies are limited, and most of the studies have been conducted in women with a history of breast ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0201/p457.html

Management of Histologic Abnormalities of the Cervix - American Family Physician

Jan 1, 2006 - The American Society for Colposcopy and Cervical Pathology sponsored a consensus conference in 2001 to develop evidence-based guidelines for women with histologic abnormalities of the cervix. The options for management of cervical intraepithelial neoplasia 1, 2, and 3 are ranked ...

American Family Physician : Article

https://www.aafp.org/afp/2006/0101/p105.html

IVF Therapy for Unexplained Infertility - Cochrane for Clinicians - American Family ...

Jan 1, 2006 - Although IVF is used routinely for the treatment of unexplained infertility, there is limited evidence to show that it is more effective than expectant management, and there is insufficient evidence to recommend it as an alternative to other therapies such as clomiphene citrate ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2006/0101/p63.html

Ethinyl Estradiol/Levonorgestrel (Seasonale) for Oral Contraception - STEPS - American ...

Apr 15, 2005 - Women using ethinyl estradiol/levonorgestrel can expect similar or improved effectiveness and fewer menstrual cycles. Due in part to an increased incidence of unexpected bleeding in the first six months of use, a greater percentage of women will discontinue this regimen than will those ...

American Family Physician : STEPS

https://www.aafp.org/afp/2005/0415/p1581.html

Dysmenorrhea - American Family Physician

Jan 15, 2005 - Dysmenorrhea is the leading cause of recurrent short-term school absence in adolescent girls and a common problem in women of reproductive age. Risk factors for dysmenorrhea include nulliparity, heavy menstrual flow, smoking, and depression. Empiric therapy can be initiated based on a ...

American Family Physician : Article

https://www.aafp.org/afp/2005/0115/p285.html

Emergency Contraception - American Family Physician

Aug 15, 2004 - Women can use emergency contraception to prevent pregnancy after known or suspected failure of birth control or after unprotected intercourse. Many patients do not ask for emergency contraception because they do not know of its availability. Emergency contraception has been an off-label...

American Family Physician : Article

https://www.aafp.org/afp/2004/0815/p707.html

Vaginal Estrogen Preparations for Relief of Atrophic Vaginitis - Cochrane for ...

May 1, 2004 - Vaginal estrogen preparations are safe and effective as short-term treatment in patients with vaginal atrophy who are not candidates for systemic hormone therapy. Compared with estradiol products, conjugated equine estrogen creams may be associated with a higher incidence of adverse ...

American Family Physician : Cochrane for Clinicians

https://www.aafp.org/afp/2004/0501/p2111.html

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